A5032713286- Estrogen and related hormone effects
- Endometriosis Research and Treatment
- Menopause: Health Impacts and Treatments
- Phytoestrogen effects and research
- Medical and Biological Sciences
- Cancer Risks and Factors
- Education and Social Development in Ukraine
- Gynecological conditions and treatments
- Human Health and Disease
- Healthcare Systems and Public Health
- Endometrial and Cervical Cancer Treatments
- Medical and Agricultural Research Studies
- Bone health and osteoporosis research
- Agriculture and Biological Studies
- Global Health Care Issues
- Cardiovascular Disease and Adiposity
- Medicinal plant effects and applications
- Pelvic floor disorders treatments
- Reproductive System and Pregnancy
- Gout, Hyperuricemia, Uric Acid
- Health and Conflict Studies
- Uterine Myomas and Treatments
- Nutrition, Genetics, and Disease
- Glutathione Transferases and Polymorphisms
- Ureteral procedures and complications
Institute of Pediatrics, Obstetrics, and Gynecology named after acad. O.M. Lukyanova of the National Academy of Medical Sciences of Ukraine
2018-2024
Kyiv City Clinical Oncology Center
2023
National Academy of Medical Sciences of Ukraine
2019-2023
National Academy of Sciences of Ukraine
2023
National Cancer Institute
2023
Background. Postmenopausal osteoporosis (PMO), which is developed due the estrogen defi ciency in women after menopause, most common type of systemic osteoporosis. The latest Ukrainian recommendation for its management requires revision to new data from high-quality research performed recent years. purpose was develop a guideline on diagnosis, prevention, and treatment PMO based an analytical analysis modern literary sources order improve awareness medical community Ukraine. Methodology. To...
This document provides an overview of existing diagnosis and treatment methods menopausal disorders in women, proposed algorithms for this disease to prevent heart diseases, osteoporosis improve the quality ukrainian women life.Climacteric is a physiological transition period woman’s life during which reproductive system involutive processes against age-related changes are dominated body, characterized by reduction menstrual generative function due genetically programmed cessation ovarian...
Approaches to the diagnosis and treatment of abnormal uterine bleeding (AUB) are constantly updated due new results clinical studies in process revising international guidelines. These updates need be implemented practice. Therefore, on October 20, 2023, II Ukrainian Forum experts AUB was held, key provisions which outlined this resolution.A multi-level three-component classification system «HyPO-P + GAIN-FIT-PIE» developed by International Federation Gynecology Obstetrics (FIGO) 2022...
Background. Experts observe that Russia’s war against Ukraine led to a significant decline in the demographic situation and caused severe impact on reproductive health of women. Objective review: assess predict consequences war-related stress women residing various zones - zones, adjacent areas, remote territories, even abroad; managing menopausal disorders with premature menopause perimenopause remotely becomes crucial due existing limitations in-person gynecological consultations. Analysis...
On November 23, 2023, the V International Forum of Experts on Menopausal Hormone Therapy (MHT) was held. The Expert Council’s working group included leading experts in field endocrine gynaecology and related areas from Azerbaijan, Armenia, Georgia, Kazakhstan, Moldova, Uzbekistan, Ukraine.The noted importance dialogue understanding between doctor patient, need for interdisciplinary integration doctors those specialties that deal with women’s health issues. Close cooperation specialists who...
Menopause is a natural and inevitable physiological process of the decline reproductive function due to decrease in ovarian function, which every woman has face after about 45–60 years. During this period hormonal changes female body needs support more than ever, because quality life modern directly depends on it.The question menopausal hormone therapy (MHT) safety relation risk breast cancer perennial subject research, studied debated medical literature for 20 time, several different...
The level of awareness about the problems maintaining health and quality life in menopause is an extremely important issue not only among women appropriate age, but also doctors various specialties. Founded on initiative specialists State Institution “E.M. Lukyanova Instituteof Pediatrics, Obstetrics Gynecology NAMS Ukraine”, social information project “Femininity Future” aimed specifically at assessing status, frequency examination aged 40+; drawing attention to need for regular application...
The global aging of the population leads to a significant increase in demographic burden on society, puts heavy economy and causes structural changes sphere social security. Therefore, problem maintaining health women peri- post-menopause becomes extremely important for public health. It is this period that number somatic mental diseases appear significantly affect quality overall life span woman. Inevitably, menopausal manifestations change hormone levels various symptoms, including...
Objective. To compare the clinical efficacy of monotherapy with menopausal hormonal therapy (climonorm) in treatment genitourinary syndrome menopause effectiveness by M-anticholinergic mirabegron (betmiga) and a combination these drugs.Materials methods. The randomization method was used to form 3 groups 30 persons each, whom various types were applied: exclusively, climonorm drugs. determine severity symptoms its dynamics process, Menopause Rating Scale used. Barlow scale assess impact...
About 10% of the world's populations are menopausal women. This period coincides with most active social and professional activities almost every woman. In addition to typical manifestations, this age stage is characterized by metabolic syndrome, which caused estrogen deficiency found in 35–49% women older groups.Modern approaches treatment prevention disorders include following principles: lifestyle changes, hormone therapy (MHT), non-hormonal (drugs hormone-like effects, phytoestrogens,...
Current classification of abnormal uterine bleeding, review diagnostic methods and treatment strategies the condition are presented in article. Moreover, evidence based algorithms diagnosis this considering features health care system Ukraine given
Recent scientific studies show that fat tissue is not a passive metabolism depot, as previously thought, but manifests itself an active endocrine organ. Pathological processes occurring in adipose with its hypertrophy during weight gain are considered links carcinogenesis more than 20% of malignant tumors, including endometrial and breast cancer.The aim the research was to study effect excess (BMI >30) on development hyperplasia women reproductive age menopause.The medical histories 62...
The problems of aging women both in the world and our country are becoming increasingly relevant. sharp increase incidence among age category, which coincides with menopause, is a serious argument for considering this period associated changes as one priorities modern medicine. Already today, despite general tendency to population, third life majority falls on post-menopausal period, acquires special social even state significance. However, these begin at younger age, requires close...
Genitourinary menopausal syndrome is characterized by urogenital and sexual symptoms (vaginal dryness itching, urinary incontinence, dyspareunia, anorgasmia). According to many experts, the of genitourinary require special attention, since women are often silent do not complain about its manifestations.Purpose study. Treatment optimization vulvar vaginal atrophic changes that associated with estrogen deficiency in perimenopausal women.Materials methods. 41 infectious complications were...
Purpose of the study. To assess sclerosis mammary arteries (SMA) frequency depending on age and duration menopause by conducting mammography in studied women perimenopausal age.Materials methods. examine morphological functional state gland was performed a clinical examination glands which included examination, palpation, bilateral mammography. Together with assessment gland, were evaluated for their sclerosis. The severity menopausal syndrome assessed using Menopausal Rating Scale. 584...
Climacteric is a physiological transition period in woman’s life during which the reproductive system involutive processes against age-related changes are dominated body, and characterized by reduction of menstrual generative function due to genetically programmed cessation ovarian function.There 4 periods menopause: menopausal period, menopause, perimenopause menopause.This document provides an overview existing diagnosis treatment methods disorders women, proposed algorithms for this...
The document was approved at an expanded meeting of the Ukrainian Society Gynecological Endocrinology with involvement all board members and representatives Association Obstetricians-Gynecologists Ukraine, Pharmacologists Anesthesiologists as well during Third School Reproductive international participation ISGE 19–20.03.21.The COVID-19 pandemic has significantly impacted medical practice, in terms organizational clinical practices, posing a number complex contradictory challenges for...
The study to examine the effi cacy and safety of herbal remedies Vimens Menorma in treatment patients with abnormal uterine bleedings reproductive period was performed.70 women age (35–45 years) prolonged menstrual bleeding were examined. 35 took 1 capsule time a day for 3 months; within months conjunction tablet 2 times 3–5 days before menstruation until their completion.There following results treatment: dynamics clinical manifestations occurred both groups – almost all reported about...
Clinical lecture is intended for general practitioners – family doctors who provide medical assistance to women with menopausal disorders and are based on the Unified clinical protocol of primary, secondary (specialized), tertiary (highly specialized) heath care “Menopausal other in perimenopause” approved by order Ministry Health Ukraine dated June 17, 2022 No. 1039.Clinical provides methods algorithms diagnosis treatment associated menopause disorders, which will allow forming a...
Introduction.Obesity is associated with chronic inflammation and colorectal cancer (CRC).In CRC liver metastases adjacent tissue defects are formed in the mitochondrial electron transport chain that causes dysfunction, activation of redox-molecules (superoxide anion (SR), NO) generation sources matrix metalloproteinases (MMP-2, MMP-9) activity.Radical oxygen species also take a part regulation xanthine/xanthine oxidase reaction.In human organs xanthine (XO) involved pathogenesis various...
Objective of the study was to analyze particulars morphofunctional changes in pelvic organs under conditions stress urinary incontinence and experimental vaginal prolapse.Materials methods. The studies were conducted on 50 sexually mature white female rats divided into three groups. first control group consisted intact animals; the2-nd animals with replicated model; 3-rd a combined model, which, after replication vault fixation sacro-uterine ligaments broken, thus causing prolapse. After...
The results of a large number studies indicate that the incidence malignant transformation hyperplasia endometrium increases significantly with age. Important in predicting likelihood hyperproliferative endometrial disease postmenopausal women is clear understanding causative factors lead to pathological proliferation period physiological decline hormonal activity.Purpose study. To investigate frequency and structure somatic morbidity diseases postmenopause determine place endocrine...
The objective: to evaluate the results of a comparative analysis clinical efficacy various compositions, combination and pharmacological effects drugs (antispasmodic, hormones, plant origin) for symptoms lower urinary tract in women premenopausal period.Materials methods. treatment 120 with was studied. complaints, uroflow metrics, sociological survey identify menopausal syndrome by MRS scale, as well level anxiety S. Spielberg scale were evaluated criteria its assessment dynamics before...
In modern conditions, the peak of professional activity many women falls precisely during period perimenopause. Therefore, maintaining physical fitness, beauty, health, sexuality, femininity, learning ability, self-improvement and interest in life is very important this period. Menopausal hormone therapy (MHT) prescribed for prevention elimination menopausal disorders. It to differentiate selection IHT, taking into account state health woman study concomitant pathology, as well modes its...