Background: Platelet-rich plasma (PRP) has been recently used to enhance and accelerate the healing of musculoskeletal injuries diseases, but evidence is still lacking, especially on its effects after rotator cuff repair. Hypothesis: accelerates recovery arthroscopic repair in pain relief, functional outcome, overall satisfaction, enhanced structural integrity repaired tendon. Study Design: Cohort study; Level evidence, 2. Methods: Forty-two patients with full-thickness tears were included....

We have examined the results obtained with 72 NexGen legacy posterior stabilised-flex fixed total knee replacements in 47 patients implanted by a single surgeon between March 2003 and September 2004. Aseptic loosening of femoral component was found 27 (38%) at mean follow-up 32 months (30 to 48) 15 knees (21%) required revision 23 (11 45). compared radiologically-loose revised those which had remained well-fixed identify factors contributed this high rate aseptic loosening. Post-operatively,...

The bone-patellar tendon-bone has been widely used and considered a good graft source. quadriceps tendon was introduced as substitute source for tendon-bone. We compared the clinical outcomes of anterior cruciate ligament reconstructions using central tendon-patellar bone autografts. selected 72 patients who underwent unilateral reconstruction between 1994 2001 matched age gender with bone. All were followed up more than 2 years. assessed laxity, knee function Lysholm International Knee...

Postoperative wound and infectious complications after total knee arthroplasty (TKA) cause poor overall outcomes increase health care costs, particularly among patients with diabetes mellitus, who have greater risks of infection. 1,2)In particular, recent evidence suggests that hyperglycemia plays a significant role in the development postoperative infections, 3,4) it has also been reported to Background: The authors examined whether preoperative glucose control, as indicated by hemoglobin...

Abstract Background The optimal alignment target for unicompartmental knee arthroplasty (UKA) remains controversial, and literature suggests that its impact on patient-reported outcome measures (PROMs) varies. purpose of this study was to identify the relationship between changes in coronal plane (CPAK) PROMs patients who underwent UKA. Methods A retrospective analysis 164 UKA conducted. types CPAK categorized into unchanged, minor (shift an adjacent type, e.g., type I II or IV), major...

Introduction. Knee osteoarthritis (OA) can affect the hip and ankle joints, as these three joints operate a kinetic/kinematic chain while walking. Purpose. This study was performed to compare (1) joint gait mechanics between knee OA control groups (2) investigate effects of on ipsilateral joint. Methods. The group included 89 patients with end-stage 42 age- sex-matched controls without pain or OA. Kinetic kinematic parameters were evaluated using commercial optoelectric analysis system....

The gelatin-methacryloyl (GelMA) polymer suffers shape fidelity and structural stability issues during 3D bioprinting for bone tissue engineering while homogeneous mixing of reinforcing nanoparticles is always under debate. In this study, amorphous calcium phosphates micro/nanoparticles (CNP) incorporated GelMA synthesized by developing specific sites gelatin structure-based nucleation stabilization in a one-pot processing. process ensures homogenous distribution CNPs different...

Abstract Senescent cells increase in many tissues with age and induce age‐related pathologies, including osteoarthritis (OA). chondrocytes (SnCs) are found OA cartilage, the clearance of those prevents progression. However, targeting SnCs is challenging due to absence a senescent chondrocyte‐specific marker. Therefore, we used flow cytometry screen select chondrocyte surface markers cross‐validated published transcriptomic data. Chondrocytes expressing dipeptidyl peptidase‐4 (DPP‐4),...

Lee, Sahnghoon MD, PhD; Seong, Sang Cheol Jo, Chris Hyunchul Han, Hyuk Soo MD; An, Joon Hwan Myung Chul PhD Author Information

Abstract Background The chondrogenic differentiation of mesenchymal stem cells (MSCs) is regulated by many factors, including oxygen tensions, growth and cytokines. Evidences have suggested that low tension seems to be an important regulatory factor in the proliferation various MSCs. Recent studies report synovium-derived (SDSCs) are a potential source for repair articular cartilage defects. But, effect on SDSCs has not characterized. In this study, we investigated effects hypoxia...

Knee osteoarthritis (KOA) is a leading cause of disability among elderly adults, and it causes pain discomfort limits the functional independence such adults. The aim this study was development an automated classification model for KOA, based on Kellgren-Lawrence (KL) grading system, using radiographic imaging gait analysis data. Gait features highly associated with radiological severity KOA identified from our previous study, in addition to image extracted deep learning network, namely,...

The application of artificial intelligence and large language models in the medical field requires an evaluation their accuracy providing information. This study aimed to assess performance Chat Generative Pre-trained Transformer (ChatGPT) 3.5 4 solving orthopedic board-style questions.

Abstract Background Fine-grained classification deals with data a large degree of similarity, such as cat or bird species, and similarly, knee osteoarthritis severity [Kellgren–Lawrence (KL) grading] is one fine-grained task. Recently, plug-in module (PIM) that can be integrated into convolutional neural-network-based transformer-based networks has been shown to provide strong discriminative regions for classification, results outperformed the previous deep learning models. PIM utilizes each...

Allografts are preferred in certain cases of revision anterior cruciate ligament reconstructions to avoid additional graft harvesting and fill enlarged tunnels. The clinical outcomes quadriceps tendon-patellar bone allograft reconstruction not well-known. This study was performed evaluate the using allografts. Patients who underwent with allografts a minimum follow-up 2 years were retrospectively reviewed. Their mean length 33.5 ± 19.5 months. Outcomes including scores (Lysholm,...

Abstract Introduction Prosthetic joint infection (PJI) is one of the most common and detrimental complications total knee replacement arthroplasty (TKA). Despite extensive efforts, including two-stage reimplantation, to eradicate PJI, it still recurs in a substantial number patients. However, risk factors recurrence after reimplantation have not been established. In this study, hypothesized that there will be certain for PJI knee. Materials methods From March 2002 December 2022, 65 knees...

Abstract Background Patellofemoral pain syndrome (PFPS) is one of the most common conditions affecting knee joint, yet its pathomechanics remain unclear. The aim this study was to investigate changes in muscle activation and gait patterns analyze relationship between kinetic patients with PFPS. Methods This included 31 PFPS 28 healthy volunteers without any symptoms. sagittal plane motion representing primary movement evaluated identify patterns. Electromyography (EMG) used measure vastus...