Christine M. McDonald

ORCID: 0000-0003-1231-9003
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About
Contact & Profiles
Research Areas
  • Child Nutrition and Water Access
  • Trace Elements in Health
  • Iron Metabolism and Disorders
  • Global Maternal and Child Health
  • Child Nutrition and Feeding Issues
  • Infant Nutrition and Health
  • Poverty, Education, and Child Welfare
  • Obesity, Physical Activity, Diet
  • Food Security and Health in Diverse Populations
  • Nutritional Studies and Diet
  • Birth, Development, and Health
  • Folate and B Vitamins Research
  • Breastfeeding Practices and Influences
  • Hemoglobinopathies and Related Disorders
  • Viral gastroenteritis research and epidemiology
  • Sodium Intake and Health
  • Body Composition Measurement Techniques
  • Pregnancy and preeclampsia studies
  • Smoking Behavior and Cessation
  • Heavy Metal Exposure and Toxicity
  • Global Health and Epidemiology
  • Climate Change and Health Impacts
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Clinical Nutrition and Gastroenterology
  • Diet and metabolism studies

University of California, Davis
2015-2025

University of California, San Francisco
2019-2025

Primary Children's Hospital
2023

Food and Agriculture Organization of the United Nations
2022

Emory University
2022

Imperial College London
2022

Micron (United States)
2022

UCSF Benioff Children's Hospital
2018-2021

Boston Children's Hospital
2013-2018

Flinders Medical Centre
2018

Background Child undernutrition affects millions of children globally. We investigated associations between suboptimal growth and mortality by pooling large studies. Methods Pooled analysis involving 1 week to 59 months old in 10 prospective studies Africa, Asia South America. Utilizing most recent measurements, we calculated weight-for-age, height/length-for-age weight-for-height/length Z scores, applying 2006 WHO Standards the 1977 NCHS/WHO Reference. estimated all-cause cause-specific...

10.1371/journal.pone.0064636 article EN cc-by PLoS ONE 2013-05-29

Micronutrient deficiencies compromise immune systems, hinder child growth and development, affect human potential worldwide. Yet, to our knowledge, the only existing estimate of global prevalence micronutrient is from over 30 years ago based on anaemia. We aimed regional deficiency in at least one three micronutrients among preschool-aged children (aged 6-59 months) non-pregnant women reproductive age 15-49 years).

10.1016/s2214-109x(22)00367-9 article EN cc-by-nc-nd The Lancet Global Health 2022-10-11

The accurate estimation of zinc deficiency at the population level is important, as it guides design, targeting, and evaluation nutrition interventions. Plasma or serum concentration (PZC) recommended to estimate nutritional status; however, concentrations may decrease in presence inflammation. We aimed assess relation between PZC inflammation preschool children (PSC; 6–59 mo) nonpregnant women reproductive age (WRA; 15–49 y), compare different adjustment approaches, if warranted....

10.1093/ajcn/nqz304 article EN cc-by American Journal of Clinical Nutrition 2019-11-15

Introduction Moderate acute malnutrition (MAM) causes substantial child morbidity and mortality, accounting for 4.4% of deaths 6.0% disability-adjusted life years (DALY) lost among children under 5 each year. There is growing consensus on the need to provide appropriate treatment MAM, both reduce associated mortality halt its progression severe malnutrition. We estimated health outcomes, costs cost-effectiveness four dietary supplements MAM in 6–35 months age Mali. Methods conducted a...

10.1136/bmjgh-2018-001227 article EN cc-by BMJ Global Health 2019-04-01

Stunting can afflict up to one-third of children in resource-constrained countries. We hypothesized that low-grade systemic inflammation (defined as elevations serum C-reactive protein or alpha-1-acid glycoprotein) infancy suppresses the growth hormone⁻insulin-like factor (IGF) axis and is associated with subsequent stunting. Blood samples 590 from periurban Dar es Salaam, Tanzania, were obtained at 6 weeks months age part a randomized controlled trial. Primary outcomes stunting,...

10.3390/nu10091158 article EN Nutrients 2018-08-24

Progress improving zinc nutrition globally is slowed by limited understanding of population status. This challenge compounded when small differences in measurement can bias the determination deficiency rates. Our objective was to evaluate analytical accuracy and precision among different instrument types sample matrices using a standardized method. Participating laboratories analyzed content plasma, serum, liver samples, controls, method based on current practice. Instrument calibration...

10.1007/s12011-021-02883-z article EN cc-by Biological Trace Element Research 2021-08-28

ABSTRACT Recognizing the broader accessibility of iodized salt compared to wheat flour, Ethiopian government is considering fortification with folic acid, and possibly vitamin B 12 , address high incidence neural tube defects (NTDs) in Ethiopia. To prepare for this program, we assessed practices related edible procurement consumption, acceptability novel salts fortified iodine acid (double‐fortified salt, DFS) or iodine, (triple‐fortified TFS) (IS). We surveyed 840 women reproductive age...

10.1002/fsn3.70012 article EN cc-by Food Science & Nutrition 2025-01-01

ABSTRACT In Bangladesh, anaemia is estimated to affect 52% of children 6–59 months, with the youngest (6–23 months) experiencing highest levels (71%). Micronutrient powders (MNPs) are designed increase micronutrient intake in young children; however, some settings, prevalence may remain elevated despite high coverage MNPs. a secondary analysis Zinc Powders trial (ZiPT), we identified risk factors that were associated among Bangladeshi 9–11 months age who received standard 15‐component MNPs,...

10.1111/mcn.13806 article EN cc-by Maternal and Child Nutrition 2025-02-10
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