A5051803782- Nanoparticle-Based Drug Delivery
- Advanced Drug Delivery Systems
- RNA Interference and Gene Delivery
- Dendrimers and Hyperbranched Polymers
- Graphene and Nanomaterials Applications
- Advanced Polymer Synthesis and Characterization
- Inhalation and Respiratory Drug Delivery
- Nanoplatforms for cancer theranostics
- Computational Drug Discovery Methods
- Tuberculosis Research and Epidemiology
- Drug Solubulity and Delivery Systems
- Supramolecular Self-Assembly in Materials
- Synthesis and Characterization of Heterocyclic Compounds
- Nanocluster Synthesis and Applications
- Malaria Research and Control
- Gas Sensing Nanomaterials and Sensors
- Surfactants and Colloidal Systems
- Data Management and Algorithms
- Saffron Plant Research Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Inflammatory Bowel Disease
- Nanoparticles: synthesis and applications
- Multiple Myeloma Research and Treatments
- Diagnosis and treatment of tuberculosis
- Cancer Research and Treatment
Khalifa University of Science and Technology
2024
Central University of Rajasthan
2015-2023
University of Rajasthan
2015
Several bacterial strains have developed resistance against commercial antibiotics, and interestingly, supramolecular nanomaterials shown considerable advantages for antibacterial applications. However, the main challenges in adopting nanotechnology studies are random aggregation, compromised toxicity, multi-step preparation approaches, unclear structure-function properties. Herein, we designed amphiphilic tripeptide that acts as a reducing capping agent silver metal to form silver-peptide...
Development of a biodegradable nanoplatform poly(lactic-co-glycolic acid) (PLGA) for co-delivery two drugs is hugely imperative and beneficial in anticancer therapeutics. In this study, natural phytoconstituent, crocin (carotenoid), commonly prescribed drug, doxorubicin, was attempted using nanoparticulate platform the form PLGA nanoparticles. Doxorubicin chemically conjugated, while encapsulated physically prepared nanoparticles (PDCR NPs). Prepared NPs were well-characterized size, ζ,...
Primaquine phosphate (PQ) is mainly used as a radical cure therapy to eradicate relapse of malaria at the liver stage, which particularly caused by P. falciparum and vivax. In present study, PQ-loaded galactosylated gelatin nanoparticles (Gel-LA-PQ-NPs) were formulated using one-step desolvation technique. The mean particle size Gel-LA-PQ-NPs was found be 93.48 ± 6.36 nm with zeta potential 4.80 0.20 mV having 69.90 1.53% encapsulation efficiency. Electron microscopy demonstrated that NPs...
Successful delivery of a chemotherapeutic agent like bendamustine still remains challenge in clinical conditions chronic lymphatic leukemia (CLL), non-Hodgkin lymphoma (NHL), and multiple myeloma. We have conjugated to polyamidoamine (PAMAM) dendrimers after conjugating with N-(hydroxyethyl)maleimide (spacer) via an ester bond. The particle size PAMAM-bendamustine conjugate was 49.8 ± 2.5 nm. In vitro drug release resulted sustained improved solution stability up 72 h. 24 h cytotoxicity...
The proposed study involves delivering drug/bioactive using a single nanoplatform based on poly lactic-co-glycolic acid (PLGA) for better efficacy, synergistic effect, and reduced toxicity. PLGA was conjugated to doxorubicin (D1), this conjugate used encapsulation of naringenin (D2) develop loaded PLGA-doxorubicin nanoparticles (PDNG). PDNG NPs were 165.4 ± 4.27 nm in size, having 0.112 0.035 PDI, with -10.1 2.74 zeta potential. surface morphology confirmed through transmission electron...