The correlation between chronic obstructive pulmonary disease (COPD) and Type 2 diabetes mellitus (T2DM) has long been recognized, but their shared molecular underpinnings remain elusive. This study aims to uncover common genetic markers pathways in COPD T2DM, providing insights into crosstalk. Utilizing the Gene Expression Omnibus (GEO) database, we analyzed gene expression datasets from six five T2DM studies. A multifaceted bioinformatics approach, encompassing limma R package, unified...

To investigate the mechanisms underlying initiation of sexual cell cycle in eukaryotes, we have focused on cyclins and cyclin-dependent kinases (CDKs) well-studied model ciliate, Tetrahymena thermophila We identified two genes, CDK19 CYC9, which are highly co-expressed with mating-associated factors MTA, MTB HAP2. Both CYC9 were found to be essential for mating T. Subcellular localization experiments suggested that these proteins located at oral area, including conjugation junction or...

ABSTRACT Novel fluorine containing siloxane monomer, namely, 4‐trifluoromethylphenylmethyl cyclosiloxane ( PF3 ) and mixed including both P unit trifluoropropyl F were successfully synthesized in this study. Furthermore, their series vinyl‐terminated copolymers with different compositions synthesized. The microstructures of investigated by 1 H NMR, 29 Si 19 Fourier transform infrared spectroscopy, differential scanning calorimetry (DSC). results characterizations confirmed that the exhibited...

The high temperature resistance of silicone rubber (SR) could be significantly improved by adding hematite (α-Fe₂O₃).

The multiple mating type system of the Ciliate Tetrahymena thermophila is a self/non-self recognition system, whose specificity resides in head-to-head, functionally distinct pair genes, MTA and MTB. We have now sequenced analyzed these genes nine additional species. conclude that MTB are derived from common ancestral gene co-evolved for at least ∼150 Myr. show T. shanghaiensis, perpetual selfer (unisexual) species, has single pair, likely different specificity. document recent replacement...

To improve the sealing performance and prolong service life of internal mixer’s end face mechanical seal, surface texture technology was introduced to seal in this paper. Different arrangements isosceles right triangle textures were designed on rotating ring study effects parameters working textured seal. The results indicate that under steady-state conditions, different produce obvious hydrodynamic pressure cause oil film capacity. Meanwhile, Rt2 arrangement can obtain lowest leakage....

A method for synthesizing bis(silymethyl)-<italic>m</italic>-carborane has been developed, the yield was reached up to 88%. The intermediate Si–Br compound could be functionalized, Si–OH, Si-vinyl, Si-ethynyl and Si–H of bissilylmethyl-<italic>m</italic>-carborane were synthesized.

ABSTRACT Trifluoropropylmethylsiloxane–phenylmethylsiloxane gradient copolysiloxanes were synthesized by anionic and cationic ring‐opening polymerization (ROP) of 1,3,5‐tris(trifluoropropylmethyl)cyclotrisiloxane ( ) phenylmethylcyclotrisiloxane ). The analysis reactivity ratios revealed that the toward ROP was higher than ; however, exhibited lower compared with during ROP. AB BAB type copolymers obtained because a difference in monomers. microstructure characterized 29 Si NMR spectroscopy,...

(iScience 24, 101950-1–101950-16, January 22, 2021) In the originally published version of this article, authors reported an incorrect entry, namely “Synclonal” in ‘MTD pattern” column, rows 5 (for species borealis) and 6 canadensis) Table 1. This entry is now corrected with appropriate “Karyonidal”. addition, all names appear “italics” no capital letters. The correct table appears below.Tabled 1Table Mating type systems Tetrahymena investigated articleClade∗SubcladeaSpecies# typesMTD...

Purpose This paper aims to study the influence of three-column groove shell radius, ball lubricating oil viscosity and elastic modulus on thermal elastohydrodynamic lubrication (TEHL) characteristics optimisation ball-type tripod universal joint. Design/methodology/approach The point contact TEHL model joint was developed, multi-grid method used solve it. analysed. Further, performance carried out by Kriging approximation combined with multi-objective particle swarm (MOPSO) algorithm....

One-pot reactions allow for the rapid synthesis of complex molecules without requiring isolation intermediates. The authors present a method highly substituted tetrahydrofurans by rhodium(II)-catalyzed OH insertion aryldiazoacetates into allylic alcohols, followed base-induced intramolecular 1,4-addition. products are formed as single diastereomers.

Experiment has proved that the rate of impurity removal depends on pressure and temperature vacuum chamber during using electron beam to smelt silicon, amount removed-impurity time when other conditions are same. In actual production process, smelting is a decisive factor while certain due melting power. To avoiding influence human control improving quality production, thinking cooling water estimate state material metal considered. We try use change judge silicon all melted evaluate...

To improve the friction and sealing performance of end-face seal device in internal mixer, surface texture technology was introduced into device. Based on hydrodynamic lubrication theory, effects different shape textures under steady unsteady conditions were simulated, friction-wear experiments carried out by Swiss Anton Paar Friction-Wear Tester TRB3. The theoretical study indicates that same conditions, effect Ellipse⊥ Triangle⊥ textured seals are better, with lower leakage better average...