A5072512920- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Ophthalmology and Eye Disorders
- Ocular Diseases and Behçet’s Syndrome
- Ophthalmology and Visual Impairment Studies
- Retinal and Macular Surgery
- Neurological Disorders and Treatments
- Heart Rate Variability and Autonomic Control
- Intraocular Surgery and Lenses
- Radiation Dose and Imaging
- Circadian rhythm and melatonin
- Inflammatory mediators and NSAID effects
- Photodynamic Therapy Research Studies
- Prostate Cancer Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Cancer Treatment and Pharmacology
- Biometric Identification and Security
- Cerebral Venous Sinus Thrombosis
- Optical measurement and interference techniques
University of Yamanashi
1997-2014
University of Yamanashi Hospital
2009
Japan Patent Office
2006
Krankenhaus vom Roten Kreuz
2004
Red Cross Hospital
2004
To investigate whether the LOC387715/ARMS2 variants are associated with an angiographic phenotype, including lesion size and composition, in subfoveal polypoidal choroidal vasculopathy.Ninety-two subjects symptomatic vasculopathy, whose visual acuity was from 0.1 to 0.5 on Landolt chart, were genotyped for LOC387715 polymorphism (rs10490924) using denaturing high-performance chromatography. The composition size, evaluated by evaluators who masked genotype. Lesion assessed greatest linear...
Purpose: The aim of this study was to evaluate the efficacy and safety bimatoprost ophthalmic solution 0.03% (bimatoprost) in Japanese normal-tension glaucoma (NTG) patients with an intraocular pressure (IOP) 18 mmHg or less. Methods: Bimatoprost instilled into unilateral conjunctival sac NTG a baseline IOP time courses IOP, hyperemia, superficial punctate keratitis, adverse events were examined at 2, 4, 8, 12 weeks post instillation. Results: Thirty-two 38 enrolled (mean age, 64.1 ± 12.6...
To compare circadian rhythm of autonomic nervous function in patients with normal-tension glaucoma subjects normal eyes.Thirty-two and 32 age-matched who had no history systemic disorders currently treated disorders, especially diseases the system, were studied. An ambulatory electrocardiogram was installed that recorded heartbeats for 48 hours. Low-frequency high-frequency values calculated as markers system status based on heart-rate variability using a power-spectrum analysis.The...
Purpose To compare the newly developed scanning peripheral anterior chamber depth analyzer (SPAC) with Van Herick technique, Shaffer grading system, and ultrasound biomicroscopy (UBM), in terms of accuracy measurement (ACD). Methods The subjects were well-controlled glaucoma patients who being treated at University Yamanashi Hospital. Ten eyes from each 4 groups classified as grades 1 to evaluated by SPAC, UBM. All measurements performed independently on temporal side a masked fashion. SPAC...
To evaluate the efficacy and safety of newly formulated brimonidine (0.1% tartrate preserved with sodium chlorite: brimonidine) as add-on therapy in on-treatment Japanese normal-tension glaucoma (NTG) patients.Brimonidine was added to NTG patients intraocular pressures (IOP) between 13 mmHg 16 after three consecutive IOP measurements. The time courses IOP, conjunctival hyperemia, superficial punctate keratitis, adverse events were examined at 4, 8, 12 weeks instillation.Though 75 83 (31...
Purpose To assess the long-term effects of latanoprost monotherapy on intraocular pressure (IOP) reduction in Japanese patients with glaucoma. Methods Those enrolled were glaucoma who had been treated an outpatient basis for more than 5 years at Glaucoma Outpatient Clinic University Yamanashi Hospital, only ophthalmic solution as first drug choice. Subjects underwent treatment a other latanoprost, laser therapy, or surgery eliminated from study, and IOP by dropout rate causative reasons,...
We investigated patient adherence and factors related to a newly introduced prostaglandin analog timolol fixed-combination eye drops (PGTFC).The Glaucoma Research on Adherence fixed-Combination Eye in Japan (GRACE) study group performed nationwide prospective questionnaire survey. Participants this were patients with glaucoma who scheduled receive any type of PGTFC for the first time. The participants answered day introduction again at return visit 4-6 weeks after introduction. physicians...
To assess the efficacy and safety of switching from prostaglandin analog (PGA) monotherapy to tafluprost/timolol fixed-combination (Taf/Tim) therapy. Patients with primary open-angle glaucoma, normal-tension or ocular hypertension who had received PGA for at least 3 months were enrolled. examined 1, 2, after changing therapies. Subsequently, patients returned monotherapy. The parameters included intraocular pressure (IOP) adverse events. A questionnaire survey was conducted switch Taf/Tim...
Purpose: To develop a cluster system to analyze the retinal sensitivity loss of 68 test points in central 10 degrees standard automated perimetry (SAP) eyes with normal tension glaucoma (NTG). Patients and Methods: NTG who met following criteria were included: visual acuity ≥ 0.7, SAP-derived mean deviation ≥− 15 dB, pattern probability plots at least one point < 0.5% and/or two or more contiguous 1% that did not cross horizontal meridian 12 24-2 points. SAP Swedish Interactive Threshold...