- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Listeria monocytogenes in Food Safety
- Essential Oils and Antimicrobial Activity
- Orthopedic Infections and Treatments
- Bee Products Chemical Analysis
- Insect and Pesticide Research
- Total Knee Arthroplasty Outcomes
- Voice and Speech Disorders
- Vibrio bacteria research studies
- Animal Nutrition and Physiology
- Orthopaedic implants and arthroplasty
- COVID-19 Impact on Reproduction
- Tracheal and airway disorders
- Medical and Biological Ozone Research
- Reproductive System and Pregnancy
- Veterinary medicine and infectious diseases
- Plant Pathogenic Bacteria Studies
- Phytochemicals and Antioxidant Activities
- Cancer Research and Treatments
- Hepatitis Viruses Studies and Epidemiology
- Infectious Diseases and Tuberculosis
- Nosocomial Infections in ICU
- Vitamin C and Antioxidants Research
- Food Safety and Hygiene
University of Rijeka
2011-2023
Rostov Research Institute of Microbiology and Parasitology
2018
Background: Exposure to microorganisms elicts the production of cytokines. These soluble factors enhance several innate immune functions and regulate ensuing specific response aimed at limiting spread infection. Aim: This study was undertaken quantify plasma levels pro‐inflammatory cytokines during course primary Listeria monocytogenes Campylobacter jejuni Using an in vivo infection relationship between endogenous bacterial number liver infected animals examined. Methods: C57BL/6 mice were...
Campylobacter-specific bacteriophages (phages) are considered as an alternative intervention strategy to decrease the level of poultry contamination with Campylobacter, a leading cause gastroenteritis worldwide. Eradication efficiency depends primarily on phage-host interaction mediated by phage tail-spike proteins and bacterial receptors. Here, this was characterised using gene sequence analysis, neutralisation antiserum host range analysis newly isolated group III Campylobacter phages 68...
BACKGROUND Responsibility for food safety must be taken through the entire food-production chain, to avoid consumer cross-contamination. The antimicrobial activities of an Alpinia katsumadai seed extract and epigallocatehin gallate (EGCG), their combination, were evaluated against individual food-borne pathogenic strains Listeria monocytogenes, Escherichia coli Campylobacter jejuni, individually as a cocktail, in chicken-meat juice sterile minced meat models, with naturally present...
Thermotolerant Campylobacter spp. frequently cause bacterial gastroenteritis in humans commonly infected through the consumption of undercooked poultry meat. We examined jejuni heat-stress responses vitro after exposure to 48°C and 55°C. The vivo modulation its pathogenicity was also investigated using BALB/c mice intravenously with stressed C. jejuni. Regardless growth phase, culturability viability reduced This correlated altered protein profile decreased virulence properties observed...
Campylobacters have developed a number of mechanisms for responding to environmental conditions, although the different virulence properties these cells following exposure stress are still poorly understood. We analyzed in vitro responses and consequent vivo modulation Campylobacter jejuni pathogenicity BALB/c mice, as result C. (starvation, oxidative stress, heat shock). In vitro, influence starvation was milder than that shock, majority conditions influenced survival jejuni. During...
The aim of this study was to evaluate Campylobacter jejuni NTCT 11168 adhesion abiotic and biotic surfaces when grown in co-culture with Escherichia coli ATCC 11229 and/or Listeria monocytogenes 4b. Adhesion C. polystyrene Caco-2 cells Acanthamoeba castellanii lower for at least 3 log CFU/mL compared E. L. monocytogenes. Electron micrographs ultrathin sections revealed interactions host cells. In monocytogenes, all tested significantly increased more than 1 CFU/mL. There 10% higher...
<p><strong>Aim<br /></strong> To determine antimicrobial activity of honey against clinical bacterial strains and their respective reference strains. <br /><strong>Methods<br Twelve samples Croatian from various botanical origin were evaluated for four antibiotic resistant pathogens strains: Staphylococcus aureus, Acinetobacter baumannii, Pseudomonas aeruginosa Escherichia coli. Antibacterial...
We investigated the anti-Campylobacter activity of pinocembrin and its mechanism action, as well Campylobacter responses to treatment at genetic phenotypic levels, using C. jejuni NCTC 11168 a multidrug efflux system repressor mutant (11168ΔcmeR). At minimal inhibitory concentration, significantly increased cell membrane permeability Campylobacter. Interestingly, sub-inhibitory concentrations, did not alter functionality it bacterial fitness. Treatment with evoked decreased expression...
Honey is a natural food consisting mainly of sugars, enzymes, amino acids, organic vitamins, minerals and aromatic substances. In addition to specific organoleptic properties, honey also has other components that contribute its nutritional health value. Proteins, minerals, acids phenolic compounds, the most variable honey, are predominantly responsible for strong bioactive effect. Honeydew less known type with outstanding antimicrobial antioxidant properties demonstrates prebiotic effects...
Campylobacter coli are one of the most common bacteria in bacterial gastroenteritis and acute enterocolitis humans. However, relatively little is known regarding mechanisms pathogenesis host response to C. infections. To investigate influence genetic changes, we first used PCR demonstrate presence virulence genes cadF, virB11, cdtB, cdtC ceuE clinical isolate 26536, which was isolated from liver infected BALB/c mice. Sequence analyses cdtB 26536 confirmed stability these during their...
Anti-tumour necrosis factor (TNF) monoclonal antibodies have become an invaluable treatment against chronic inflammatory diseases such as rheumatoid arthritis (RA).However, due to increased risk of opportunistic infections, patients receiving anti-TNF therapy should be closely monitored for serious infections.Here, we describe a case acute Salmonella enteritidis infection joint arthroplasty that previously was functioning well, in patient infliximab RA.After prolonged antimicrobial...
Summary Adhesion of foodborne pathogens to materials industrial surfaces is an important step in their transmission through the food chain. also a prerequisite for bacterial colonisation within host, enable intracellular invasion. We define strategy reduce contamination and infection by Listeria monocytogenes , Campylobacter jejuni Escherichia coli using ethanol extract Alpinia katsumadai seeds (AlpE) epigallocatechin gallate ( EGCG ) as anti‐adhesive agents. show first time that AlpE...
ABSTRACTObjective: Research into Campylobacter jejuni pathogenesis and host responses to C. infection is needed in the fight against human campylobacteriosis.Methods: We established intravenous infections of BALB/c mice with either a food isolate or origin. Further we include PCR demonstrate presence stability putative virulence genes cadF, virbB11, cdtB, cdtC, ceuE isolates examined cytokine production IL-6, IL-12, TNF-α, IFN-γ, IL-10 livers these infected mice.Results: confirm here cdtC...
This study investigated the physicochemical properties of fir (Abies alba Mill.) honeydew honey (FHH) and its biological activity against leading foodborne bacterium Campylobacter jejuni. Antibacterial activity, bacterial growth anti-adhesion tests were performed in Mueller Hinton (MH) broth cow’s milk used as a food model. FHH from mountainous region Croatia showed antibacterial C. jejuni MH milk, with minimal inhibitory concentration (MIC) values ranging 12.5 to 50 mg/mL. A transmission...