A5004358885- Pluripotent Stem Cells Research
- CRISPR and Genetic Engineering
- Neuroscience and Neural Engineering
- Immune cells in cancer
- Diabetes and associated disorders
- Advanced Glycation End Products research
- 3D Printing in Biomedical Research
Stem Cell Institute
2020
Wellcome/MRC Cambridge Stem Cell Institute
2020
University of Cambridge
2020
Queen Mary University of London
2014
Abstract Background A major challenge for the clinical use of human pluripotent stem cells is development safe, robust and controlled differentiation protocols. Adaptation research protocols using reagents designated as research-only to those which are suitable use, often referred good manufacturing practice (GMP) reagents, a crucial laborious step in translational pipeline. However, published assist this process remain very limited. Methods We adapted research-grade derivation long-term...
ABSTRACT A major challenge for the clinical use of human pluripotent stem cells is development safe, robust and controlled differentiation protocols. Adaptation research protocols using reagents designated as research-only to those which are suitable use, often referred Good Manufacturing Practice (GMP) reagents, a crucial laborious step in translational pipeline. However, published assist this process remain very limited. Here we present new GMP-compliant protocol derive long-term...