Frederik Johannsen

ORCID: 0000-0003-1273-8785
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About
Contact & Profiles
Research Areas
  • Immunotherapy and Immune Responses
  • SARS-CoV-2 and COVID-19 Research
  • vaccines and immunoinformatics approaches
  • CAR-T cell therapy research

Rockefeller University
2023

Despite mRNA vaccination, elderly individuals remain especially vulnerable to severe consequences of SARS-CoV-2 infection. Here, we compare the memory B cell responses in a cohort and younger who received booster vaccinations. Plasma neutralizing potency breadth were similar between two groups. By contrast, absolute number SARS-CoV-2–specific cells was lower elderly. Antibody sequencing revealed that compartments more clonal less diverse. Notably, antibodies from preferentially targeted...

10.1084/jem.20230668 article EN cc-by The Journal of Experimental Medicine 2023-06-27

10.1007/s15004-022-9167-3 article DE InFo Hämatologie + Onkologie 2022-09-01
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