Hee-Jin Park

ORCID: 0000-0003-1276-7949
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Research Areas
  • Nanoparticles: synthesis and applications
  • Food Quality and Safety Studies
  • Nutrition, Health and Food Behavior
  • Bacterial biofilms and quorum sensing
  • Agriculture, Soil, Plant Science
  • Listeria monocytogenes in Food Safety
  • Marine and Coastal Research
  • Salmonella and Campylobacter epidemiology
  • Meat and Animal Product Quality
  • Microplastics and Plastic Pollution
  • Ginseng Biological Effects and Applications
  • Inhalation and Respiratory Drug Delivery
  • Bacteriophages and microbial interactions
  • Phytochemicals and Antioxidant Activities
  • Recycling and Waste Management Techniques
  • Graphene and Nanomaterials Applications
  • Food Safety and Hygiene
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Enzyme Production and Characterization
  • Effects and risks of endocrine disrupting chemicals
  • Environmental remediation with nanomaterials
  • Advanced biosensing and bioanalysis techniques
  • Ecology and Conservation Studies
  • Biosensors and Analytical Detection
  • Antimicrobial agents and applications

Korea Food Research Institute
2022-2024

Korea Institute of Toxicology
2015-2024

Jeonbuk National University
2011-2023

Korea Advanced Institute of Science and Technology
2023

Korea University
2022-2023

Kyungpook National University
2010-2022

Sungkyunkwan University
2021

Pukyong National University
2019

Kyung Hee University
2008-2017

Seoul National University
2008-2013

The mechanism of Escherichia coli inactivation by nanoparticulate zerovalent iron (nZVI) and Fe(II) was investigated using reactive oxygen species (ROS) quenchers probes, an oxidative stress assay, microscopic observations. Disruption cell membrane integrity respiratory activity observed under deaerated conditions [more disruption nZVI than Fe(II)], OH or Fe(IV) appears to play a role.

10.1128/aem.01009-10 article EN Applied and Environmental Microbiology 2010-09-25

The cupric ion mediated inactivation of Escherichia coli was enhanced by the presence hydrogen peroxide (H2O2), with increasing efficacy observed in response to concentrations H2O2. biocidal activity Cu(II)/H2O2 system is believed result from oxidative stress caused reactive oxidants such as hydroxyl radical ((•)OH), cupryl species (Cu(III)), and superoxide (O2(•-)), which are produced via catalytic decomposition In E. cells treated Cu(II) H2O2, intracellular level (•)OH Cu(III) increased...

10.1021/es403155a article EN Environmental Science & Technology 2013-11-03

This study demonstrated Escherichia coli inactivation by cupric ion (Cu[II]), focusing on intracellular generation and consumption of reactive oxygen species (ROS) including superoxide hydroxyl radials. In the presence Cu(II), levels E. decreased in a concentration-dependent manner, indicating that radical was used to reduce Cu(II) Cu(I) cells. The variation level adding negligible. Molecular scavengers did not affect efficacy excluding possibility radicals induced copper-mediated reduction...

10.1021/es302379q article EN Environmental Science & Technology 2012-09-22

Mitochondrial dysfunction and oxidative stress are frequently observed in the early stages of Alzheimer's disease (AD). Studies have shown that presenilin-1 (PS1), catalytic subunit γ-secretase whose mutation is linked to familial AD (FAD), localizes mitochondrial membrane regulates its homeostasis. Thus, we investigated how five PS1 mutations (A431E, E280A, H163R, M146V, Δexon9) FAD affect functions. Methods: We used H4 glioblastoma cell lines genetically engineered inducibly express either...

10.7150/thno.59776 article EN cc-by Theranostics 2021-01-01

Colloidal silver nanoparticles (AgNPs) have been commercialized as the typically stabilized form via addition of a variety surfactants or polymers. Herein, to examine effects stabilizing AgNPs in suspension, we modified surface bare with four type (NaDDBS, SDS, TW80, CTAB) and polymers (PVP, PAA, PAH, CMC). The was applied compare suspension stability nanotoxicity test using Escherichia coli (E. coli) model organism. Modification chemical stabilizer may be not related molecular weight, but...

10.5012/bkcs.2011.32.2.613 article EN Bulletin of the Korean Chemical Society 2011-02-20

In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified in Wuhan, China, leading to global Coronavirus Disease pandemic. The rapid spread of SARS-CoV-2 highlighted urgent need for effective vaccines. However, high cost, cold storage requirements, and scalability challenges associated with mRNA vaccines have necessitated alternative vaccine technologies. study, safety a plant-based evaluated. vaccine, an emulsion S1 antigen synthetic TLR4...

10.1080/1547691x.2025.2504401 article EN cc-by-nc Journal of Immunotoxicology 2025-05-14

Large amounts of additives are used during meat product processing to maintain quality and shelf life. With the growing interest in healthy foods, natural plant-based being as alternatives synthetic additives. In this study, six types extracts with excellent antibacterial activity were selected, their antioxidant activities against four pathogens evaluated various combinations. addition, pH, color, amount thiobarbituric acid reactive substances (TBARS), growth pathogenic microorganisms...

10.5187/jast.2022.e92 article EN cc-by-nc Journal of Animal Science and Technology 2022-12-20

The quorum sensing (QS) inhibitors that antagonize TraR, a receptor protein for N-3-oxo-octanoyl-L-homoserine lactones (3-oxo-C8-HSL), QS signal of Agrobacterium tumefaciens were developed. structural analogues 3-oxo-C8-HSL designed by in silico molecular modeling using SYBYL packages, and synthesized the solid phase organic synthesis (SPOS) method, where carboxamide bond was replaced with nicotinamide or sulfonamide to make derivatives N-nicotinyl-L-homoserine N-sulfonyl-L-homoserine...

10.1007/s10059-009-0144-6 article EN cc-by-nc-sa Molecules and Cells 2009-10-24

This study was performed to identify dietary behavior such as snack consumption, night-eating and nutrients intake associated with gestational diabetes mellitus (GDM). The conducted on 219 normal glucose tolerance (NGT) subjects 44 GDM by using a questionnaire including behavior, food frequency 3-day record. mean age, OGTT, delivery weight of were statistically higher than those in NGT. A larger proportion NGT consumed black coffee (49.8%) while the majority (61.4%) drank mixed sugar cream....

10.7762/cnr.2013.2.1.42 article EN cc-by-nc Clinical Nutrition Research 2013-01-01

This study was conducted to investigate employee food-hygiene and nutrition awareness performance the current education programs for children at child care centers kindergartens located in Seoul, Republic of Korea. A self-evaluated type questionnaire developed foodservice employees teachers using a five-point Likert scale. Employees with an employment history <1 year who were <30 years old had lowest scores performance. cooking license higher score regarding cross-contamination than those...

10.9724/kfcs.2011.27.2.045 article EN Korean Journal of Food and Cookery Science 2011-04-30

The rapid development of biomimetic materials in the field regenerative medicine has made it possible to mimic natural cellular environments and allow vitro systems replace vivo systems. In particular, emergence hexanoyl glycol chitosan (HGC) is playing an important role 3-dimensional (3D) cell culture tissue engineering. We employed HGC-coated dishes cultivate human hair follicle dermal papilla (HDP) cells 3D spheroids, assessing their ability form hair-like structures. study also tested...

10.34133/bmr.0018 article EN cc-by Biomaterials Research 2024-01-01

Owing to the residual toxicity and adverse health effects of chemical preservatives, there is an increasing demand for using natural preservatives in food. Although many extracts have been evaluated, research on their antibacterial remains insufficient. Therefore, this study aimed explore possibility developing Psidium guajava, Ecklonia cava, Paeonia japonica (Makino) Miyabe & Takeda as food preservatives. Further, effect mixing these microbial growth quality was evaluated during...

10.5851/kosfa.2023.e66 article EN cc-by-nc Food Science of Animal Resources 2023-10-23

Purpose: This study was to investigate the quality characteristics of wet noodle added with radish juice containing pulp. Methods: Wet noodles were prepared different amounts (0%, 20%, 40%, 60%, 80%, 100%, w/w) instead water. Results: As amount increased, water absorption, volume increasing rate, and turbidity soup decreased. Lightness (L) values uncooked cooked decreased addition juice, while redness (a) yellowness (b) had no tendency or decreasing, regardless juice. Moreover, lightness,...

10.9724/kfcs.2016.32.5.559 article EN Korean Journal of Food and Cookery Science 2016-10-30
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