A5062365361- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Laser-Matter Interactions and Applications
- Biochemical effects in animals
- Vitamin D Research Studies
- Eosinophilic Esophagitis
- Birth, Development, and Health
- Apelin-related biomedical research
- Urinary and Genital Oncology Studies
- Optical and Acousto-Optic Technologies
- Systemic Lupus Erythematosus Research
- Advanced Fiber Laser Technologies
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Hepatitis C virus research
- Photorefractive and Nonlinear Optics
- Fibroblast Growth Factor Research
- Liver physiology and pathology
- Pancreatic function and diabetes
- Neurological Disorders and Treatments
- Macrophage Migration Inhibitory Factor
- Diverticular Disease and Complications
- Laser Design and Applications
Chelyabinsk State Medical Academy
2020-2023
Peoples' Friendship University of Russia
2023
Ural State Medical University
2020-2023
Lotus Clinical Research
2020
Municipal Autonomous Healthcare Institution
2010
Aim. To evaluate effects of ursodeoxycholic acid (UDCA) on inflammation, steatosis and liver fibrosis atherogenesis factors in patients with non-alcoholic fatty disease (NAFLD). Materials methods. The study included 139 NAFLD who received 15 mg/kg UDCA (Ursosan ® ) per day for 24 weeks. Before after the study, function lipid metabolism, index FLI, intimamedia thickness (IMT) carotid arteries were determined. cardiovascular risk was calculated according to ASCVD 2013. Results. use led a...
In the Russian Federation, liver diseases are most frequently represented by two their nosological forms, i.e., nonalcoholic and alcoholic fatty disease (NAFLD ALD). A successful management of such patients, along with improving functional state liver, requires a careful analysis patients’ nonspecific complaints. particular, it is important to investigate asthenic syndrome, which can indirectly result in exacerbation diseases, thus incurring additional economic costs national healthcare...
Liver regeneration is an important task in the treatment of any liver diseases. The key point restoration structure, regression fibrosis and steatosis liver. Difficulties patients with steatohepatitis metabolic alcoholic etiology are associated comorbidity multicomponent drug load, problems lifestyle modification. use a complex parenteral this group increases patient compliance, minimizes risks interactions. aim study: to evaluate effect course Laennec on insulin resistance, dyslipidemia,...
Introduction . The increase in serum transaminases (ALT and AST) the persistence of their high values is associated with morbidity mortality from liver diseases. Bicyclol has anti-inflammatory antioxidant effects, which formed basis for this study. Materials methods study enrolled 51 patients (MELD < 19); hepatitis stage – 84.4%, cirrhosis 15.6%. Treatment: 75 mg/day 12 weeks. Criteria efficacy: dynamics ALT, AST, CRP; general well-being (D-FIS scale). Results After 4 weeks treatment...
Aim . This study is aimed at evaluating the efficacy and safety of Bicyclol administration in patients suffering from non-alcoholic fatty liver disease (NAFLD) («ZIGUN» research) by monitoring laboratory data non-invasive methods diagnosis fibrosis steatosis. Materials The included 93 with NAFLD average age 44 (38–49) years, having stage steatosis greater than 1st according to FibroScan (FibroScan 502 TOUCH CAP software). Patients were randomized into 2 groups: 1) main group comprised 67...
Purpose of the study. Search for relationship between cardiometabolic risk factors and 25(OH)D levels in young men with NAFLD. Materials methods. A one-time study was carried out. The included 102 aged 18 to 44 years no complaints a verified diagnosis NAFLD confirmed 70 people. All patients were divided into two groups: group I - persons (n=70); II without (n=32); age differences are not statistically significant. underwent laboratory instrumental examination. Results. In 68.6% who had...
Introduction . Non–alcoholic fatty liver disease (NAFLD) is a chronic metabolic associated with insulin resistance, high potential for progression and increased prevalence among the population of all countries. The search modifiable factors development NAFLD, especially young people, an urgent healthcare task. relationship between vitamin D availability incidence disorders in adults its contribution to NAFLD currently under active discussion. aim work was reveal components syndrome level...
Aim. This observational (non-interventional) study was aimed at obtaining data on practitioners’ commitment to prescribing rifaximin- α therapy patients with uncomplicated diverticular disease (UDD), assess patients’ adherence such prescriptions, as well physicians’ and satisfaction this drug under the conditions of outpatient practice. Materials methods . 27 research physicians in 22 centres located 15 Russian cities 250 participated an open, prospective multicentre study. The observation...
The purpose of the study : to assess clinical efficacy, dynamics liver steatosis, effect on insulin resistance and hypolipidemic, ammonia level, systemic inflammation Heptrong in patients with non-alcoholic fatty disease (NAFLD) dyslipidemia obesity. Materials methods . included 40 (23 men), age Me 48 (41–53) years, BMI 30.5 (28–34) kg / sqm. Inclusion criterion: presence hepatosis ultrasound ALT level is more than 1.5 norms. Asthenia (AVS) was detected 78% patients, abdominal pain 65%...
Objective: to improve diagnostic and therapeutic tactics in patients with cholelithiasis combination NAFLD, taking into account the impact of comorbidity. Materials methods: We examined 180 people who applied Lotos Medical Center Chelyabinsk period 2018-2020 NAFLD at age 19 65 years. The study included 128 women (72%) 52 men (28%). mean participants was 51.3±9 work took anamnestic (comorbid pathology) anthropometric data (height, body weight, mass index, waist circumference). All underwent...
Treatment of complications portal hypertention at liver cirrhosis also includes as preventive maintenance varieces bleedings a gullet various ways, and treatment hepatocellular insufficiency. The result complex with application surgical methods to stimulation regeneration transplantation fetal tissue for correction insufficiency are submitted.
Aim of the study. To estimate efficacy and safety cepeginterferon-alpha 2b (cPEG-IFNα2b) ribavirin combination for treatment chronic hepatitis C (CHC), to define necessity IL-28V genetic polymorphism diagnostics, liver elastometry scores at background antiviral therapy. Material methods. Overall 164 patients with viruses (HCV) genotypes 1, 2 3 in 4 medical centers received All cPEG-IFNα2band ribavirin. The mode dose drugs conformed existing standards. Treatment response was defined by...
One of the possible mechanisms loss energy by high intensity optical radiation in media with a quadratic nonlinearity is considered. The source losses nonphase-matched second-harmonic generation when doubled frequency lies within an absorption region crystal. A detailed study reported influence at on propagation fundamental-frequency wave for different ratios characteristic lengths (absorption, nonlinear, coherence, and quasistatic). It shown that some cases nonlinear may be considerable can...