A5018043196- Helminth infection and control
- Parasite Biology and Host Interactions
- Hormonal and reproductive studies
- Parasitic Infections and Diagnostics
- Estrogen and related hormone effects
- Nematode management and characterization studies
- Microplastics and Plastic Pollution
- Genetics, Aging, and Longevity in Model Organisms
- Recycling and Waste Management Techniques
- Toxoplasma gondii Research Studies
- Coccidia and coccidiosis research
- Gestational Trophoblastic Disease Studies
- Parasites and Host Interactions
- Ovarian function and disorders
- Trypanosoma species research and implications
- Polyamine Metabolism and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Meat and Animal Product Quality
- Chemical Reaction Mechanisms
- Parasitic Diseases Research and Treatment
- Pharmacological Effects and Assays
- Pituitary Gland Disorders and Treatments
- Cytomegalovirus and herpesvirus research
- Coenzyme Q10 studies and effects
- Prenatal Screening and Diagnostics
Centre for Environment, Fisheries and Aquaculture Science
2020-2022
University of Zurich
1985-2004
GTx (United States)
1998
Baylor College of Medicine
1973-1980
Stanford University
1978
The increasing abundance of marine litter is impacting the environment, human health and economies in South Pacific. Small Islands Developing States are particularly affected by litter, primarily due to insufficient waste management systems. For first time, was quantified characterised on 13 beaches Solomon Vanuatu Pacific region using OSPAR beach monitoring guidelines. A total 1053 (±1017) 974 (±745) items per 100 m were recorded respectively. Litter composition distribution show that...
Abstract The mismanagement of waste and subsequent presence litter in the environment is an increasingly significant problem. Globally, rivers have been shown to be a major pathway for mismanaged waste. We investigated distribution macro, meso micro along Belize river basin. North-East Atlantic OSPAR beach monitoring protocol was adapted Belize, taking into account local issues such as mangroves Sargassum sp. accumulations. On average, 77.3% items consisted plastic, most common categories...
20 healthy men, 23-34 years of age, were selected to study the potential for using an exogenous androgen as a reversible male contraceptive. The experimental design consisted 10-week control period, initial 12-week period with weekly 200 mg injections testosterone enanthate (TE), 36-week TE every 3 weeks, and 28-week recovery period. Serum concentrations increased about 50% during treatment gonadotropins became very low or undetectable essentially unresponsive LRH. Sperm density fell, 11 19...
Journal Article Ectopic and Eutopic Secretion of Chorionic Gonadotropin its Subunits in Vitro: Comparison Clonal Strains from Carcinomas Lung Placenta Get access Jeffrey M. Lieblich, Lieblich Search for other works by this author on: Oxford Academic PubMed Google Scholar Bruce D. Weintraub, Weintraub Gary H. Krauth, Krauth Peter O. Kohler, Kohler Alan S. Rabson, Rabson Saul W. Rosen JNCI: the National Cancer Institute, Volume 56, Issue 5, May 1976, Pages 911–917,...
The hamster ductus deferens cloned tumor cell line (DDT1) has been shown to contain both androgen and glucocorticoid binding activity. receptor site concentration is 1.07 x 10(-13) mol of testosterone/mg protein, testosterone (T) binds with a Kd 4.3 10(-10) M. Dihydrotestosterone (DHT) also bound the 2.99 M 1.33 mol/mg protein. order steroid affinity DHT greater than T Estradiol Progesterone. Cortisol, dexamethasone, triamcinolone acetonide do not inhibit in vivo or vitro. In free system...
Abstract Despite global efforts to monitor, mitigate against, and prevent trash (mismanaged solid waste) pollution, no harmonized typology system has been widely adopted worldwide. This impedes the merging of datasets comparative analyses. We addressed this problem by 1) assessing state comparability, 2) developing a standardized framework relational tables tools, 3) informing practitioners about challenges potential solutions. analyzed 68 survey lists assess similarities differences in...
Two human choriocarcinoma cell lines were shown to be deficient in adenosine deaminase (ADA; aminohydrolase, EC 3.5.4.4) such that they did not produce bands on starch gels after electrophoresis and histochemical staining. Radiometric assay indicated their ADA specific activity was approximately 2% of HeLa (human) controls. Subclone analysis one the this deficiency representative individual cells line. After fusion these with mouse fibroblasts having high activity, most independently...
Ovalbumin messenger RNA (mRNAov) purified from hen oviduct was injected into Xenopus laevis oocytes. The oocytes were incubated in culture medium containing [3H]leucine. Analysis of the oocyte cytosol on Sephadex G-15O columns demonstrated a peak radioactivity which cochromatographed with authentic ovalbumin. Radioactive protein contained this precipitated by ovalbumin antiserum, coelectrophoresed sodium dodecyl sulfate (SDS) and urea gels at pH 8.7, eluted same (4.8) CM-cellulose...
The hamster ductus deferens cloned tumor cell line (DDT 1 ) contains a complex steroid receptor protein that binds 3 H-labeled 5 α-dihydrotestosterone. Diethylaminoethyl (DEAE) chromatography of cytosol from these cells yields two major peaks activity. Identification this binding as cytoplasmic was confirmed by salt dissociation on sucrose gradients, stability the hormone-receptor at 0°C, and retention patterns phosphocellulose DEAE cellulose. Multiple forms exist in single homogeneous type....
Abstract Marine litter is a significant global threat. The complex and cross cutting nature involved in tackling marine requires coordinated response involving multiple sectors broad range of stakeholders. Small Island Developing States (SIDS) are particularly vulnerable to detrimental impacts on quality life economies, tourism fisheries sectors. This paper presents national Litter Action Plans (MLAP) as effective tools for coordinating responses addressing specifically outlines the process...
Summary The filarial worm Litomosoides carinii showed a rapid uptake of glucose during in vitro incubation. This proceeded linearly with time, and was significantly higher under aerobic compared to anoxic conditions. Under an atmosphere nitrogen the worms converted almost quantitatively lactate, whereas presence oxygen appreciable quantities acetate, acetoin CO 2 , addition were formed. Although aerobically only 73% carbohydrate carbon could be accounted for by latter products as well net...
A major surface constituent of Echinococcus multilocularis adult worms, referred to as an EmA9 antigen, was immunoaffinity purified and identified a high-molecular-weight glycoconjugate. Labeling studies using the monoclonal antibody MAbEmA9 indicated that this antigen undergoes regulated expression during development from larval parasite. Chemical modification carbohydrate by periodate oxidation resulted in reduced reactivity with antigen-specific antibodies. Non-reductive β-elimination...
ABSTRACT To explore the possibility of expressing membrane-anchored exodomains heterologous surface antigens in Giardia , a chimeric construct containing Toxoplasma gondii SAG1 gene was made. The system is shown here to provide means generating correctly folded proteins native and unmodified form.