- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Function and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Health disparities and outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Health Promotion and Cardiovascular Prevention
- Blood Pressure and Hypertension Studies
- Acute Myocardial Infarction Research
- Heart Rate Variability and Autonomic Control
- Global Health Care Issues
- Cardiac Valve Diseases and Treatments
- Diabetes Treatment and Management
- Cardiac Health and Mental Health
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Pulmonary Hypertension Research and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiovascular Syncope and Autonomic Disorders
- Emergency and Acute Care Studies
University of British Columbia
2016-2025
Vancouver General Hospital
2018-2025
Centre for Health Evaluation and Outcome Sciences
2022-2024
BC Innovation Council
2020-2024
St. Paul's Hospital
2014-2024
Montreal Heart Institute
2023
Université de Montréal
2023
University of Alberta
2023
St. Paul's Hospital
2017-2022
Providence Health Care Research Institute
2022
<h3>Objective</h3> To determine whether or not radiofrequency ablation (RFA) for persistent atrial fibrillation in patients with advanced heart failure leads to improvements cardiac function. <h3>Setting</h3> Patients were recruited from outpatient clinics Scotland. <h3>Design and intervention</h3> severe left ventricular dysfunction randomised RFA (rhythm control) continued medical treatment (rate control). followed up a minimum of 6 months. <h3>Main outcome measure</h3> Change ejection...
Objective To examine the risk of adverse cardiovascular (CV) events following an exacerbation chronic obstructive pulmonary disease (COPD). Methods This retrospective cohort study identified patients with COPD using administrative data from Alberta, Canada 2014 to 2019. Exposure periods were 12 months moderate or severe exacerbations; reference period was time preceding a first exacerbation. The primary outcome composite all-cause death hospitalisation for acute coronary syndrome, heart...
A modeling study conducted by Madhavi Bajekal and colleagues estimates the extent to which specific risk factors changes in uptake of treatment contributed declines coronary heart disease mortality England between 2000 2007, across within socioeconomic groups.
Our aims were to determine the pace of change in cardiovascular risk factors by age, gender and socioeconomic groups from 1994 2008, quantify magnitude, direction absolute relative inequalities. Time trend analysis was used measure inequalities age (16-54, ≥ 55 years), using repeated cross-sectional data Health Survey for England 1994-2008. Seven examined: smoking, obesity, diabetes, high blood pressure, raised cholesterol, consumption five or more daily portions fruit vegetables, physical...
Various noninvasive intermittent rhythm monitoring strategies have been used to assess arrhythmia recurrences in trials evaluating pharmacological and invasive therapeutic interventions for atrial fibrillation (AF). We determined whether a frequency duration of could be identified that accurately detects approximates the AF burden derived from continuous using an implantable cardiac monitor (ICM).The history 346 patients enrolled CIRCA-DOSE trial (Cryoballoon Versus Contact-Force Irrigated...
Abstract Aims Atrial tachyarrhythmia recurrence ≥30 s remains the primary endpoint of clinical trials; however, this definition has not been correlated with outcomes or pathophysiological processes. This study sought to determine atrial duration and burden associated meaningful outcomes. Methods results The time every episode recorded on implantable cardiac monitor were evaluated. Healthcare utilization quality life in year following ablation prospectively collected. Three hundred forty-six...
Atrial fibrillation (AF) is a chronic progressive disorder. Persistent forms of AF are associated with increased rates thromboembolism, heart failure, and death. Catheter ablation modifies the pathogenic mechanism progression. No randomized studies have evaluated impact energy on progression to persistent atrial tachyarrhythmia.
Limited empirical evidence informs fitness-to-drive recommendations after implantable cardioverter-defibrillator (ICD) implantation. Cohort designs can be deceptive because ICD recipients differ from control individuals and may temporarily cease driving This study sought to generate inform medical restrictions We used population-based data identify all drivers involved in a serious motor vehicle crash British Columbia, Canada, 1997 2019. Exposure was defined as implantation the 6 months...
To determine the number of patients with a primary or secondary prevention implantable cardioverter-defibrillator (ICD) indication who are eligible for subcutaneous ICD (S-ICD) implantation according to S-ICD manufacturer's surface electrocardiogram (ECG) screening template. One hundred and ninety-six non-paced ventricle were assessed using erect supine ECG limb lead recordings simulate three sensing vectors. Each was scrutinized by two independent observers. Subcutaneous eligibility...