- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- Visual perception and processing mechanisms
- Advanced Optical Imaging Technologies
- Adaptive optics and wavefront sensing
- Ocular Surface and Contact Lens
- Ocular and Laser Science Research
- Optical Coherence Tomography Applications
- Retinal Diseases and Treatments
- Advanced optical system design
- Image Processing Techniques and Applications
- Glaucoma and retinal disorders
- Optical measurement and interference techniques
- Higher Education in Latin America
- Retinal Imaging and Analysis
- Image and Video Quality Assessment
- Labor Law and Work Dynamics
- Infrared Target Detection Methodologies
- Satellite Image Processing and Photogrammetry
- Virtual Reality Applications and Impacts
- Education and Technology Integration
- Ergonomics and Musculoskeletal Disorders
- Health and Lifestyle Studies
- Social Sciences and Policies
Harvard University
2021-2023
Massachusetts General Hospital
2021-2023
Consejo Superior de Investigaciones Científicas
2014-2023
Instituto de Óptica "Daza de Valdés"
2014-2023
National Academies of Sciences, Engineering, and Medicine
2021
Comunidad de Madrid
2021
Universidad Carlos III de Madrid
2020
University of California System
2020
Biosensores (Spain)
2020
Innovatec (Spain)
2017
Longitudinal Chromatic Aberration (LCA) influences the optical quality of eye. However, reported LCA varies across studies, likely associated to differences in measurement techniques. We present measured subjects using wavefront sensing, double-pass retinal images, and psychophysical methods with a custom-developed polychromatic Adaptive Optics system wide spectral range (450-950 nm), control subjects' natural aberrations. psychophysically was significantly higher than that from...
Background The visual system adjusts to changes in the environment, as well within observer, adapting continuously maintain a match between coding and environment. We evaluated whether perception of oriented blur is biased by native astigmatism, studied time course after-effects following spectacle correction astigmatism habitually non-corrected astigmats. Methods Findings tested potential shifts perceptual judgments orientation 21 subjects. psychophysical test consisted on single interval...
Adaptive optics (AO) visual simulators based on deformable mirrors, spatial light modulators or optotunable lenses are increasingly used to simulate vision through different multifocal lens designs. However, the correspondence of this simulation with that obtained real intraocular (IOLs) tested same eyes has not been, our knowledge, demonstrated. We compare through-focus (TF) optical and quality produced by IOLs (M-IOLs) -bifocal refractive trifocal diffractive- projected subiect's eye those...
Astigmatic subjects are adapted to their astigmatism and perceptually recalibrate upon its correction. However, the extent which prior adaptation affects visual performance, whether this effect is axis dependent, time scale of potential changes in performance after correction not known. Moreover, possible positive interactions aberrations (astigmatism coma) might be altered recalibration astigmatism.Visual acuity (VA) was measured 25 (astigmats non-astigmats, corrected uncorrected) under...
As the human eye ages, crystalline lens stiffens (presbyopia) and opacifies (cataract), requiring its replacement with an artificial [intraocular (IOL)]. Cataract surgery is most frequently performed surgical procedure in world. The increase IOL designs has not been paralleled practice by a sophistication selection methods, which rely on limited anatomical measurements of surgeon's interpretation patient's needs expectations. We propose that future will be guided 3D quantitative imaging to...
Tunable lenses are becoming ubiquitous, in applications including microscopy, optical coherence tomography, computer vision, quality control, and presbyopic corrections. Many require an accurate control of the power lens response to a time-dependent input waveform. We present fast focimeter (3.8 KHz) characterize dynamic tunable lenses, which was demonstrated on different models. found that temporal is repetitive linear, allowed development robust compensation strategy based optimization...
While multifocal intraocular lenses (MIOLs) are increasingly implanted to correct for presbyopia, how one sees with a correction is hard explain and imagine.The current study evaluates the quality of various visual simulating technologies by comparing vision simulated MIOLs pre-operatively post-operatively in same patients.Two simulation platforms were used: (1) custom-developed adaptiveoptics (AO) system, two simulator devices: spatial light modulator (SLM) an optotunable lens operating...
Spatial-light-modulators (SLM) are increasingly used as active elements in adaptive optics (AO) systems to simulate optical corrections, particular multifocal presbyopic corrections.In this study, we compared vision with lathe-manufactured multi-zone (2-4) multifocal, angularly and radially, segmented surfaces through the same corrections simulated a SLM custom-developed two-active-element AO visual simulator.We found that perceived quality measured real manufactured SLMsimulated phase maps...
Purpose: As multifocal contact lenses (MCLs) expand as a solution for presbyopia correction, better understanding of their optical and visual performance becomes essential. Also, providing subjects with the experience vision before lens fitting critical, both to systematically test different designs optimize selection in clinic. In this study, we evaluated ability simultaneous simulator (SimVis) represent MCLs. Methods: Through focus (TF) quality center-near aspheric MCL (low, medium high...
A better understanding of visual performance with Multifocal Contact Lenses (MCLs) is essential, both in young eyes, where MCLs may be prescribed to control the progression myopia wherein optics interact accommodation, and presbyopes, are increasingly used compensate lack accommodation. In this study, we evaluated through focus acuity (TFVA) center-near three additions (low, medium high) without an addition (NoLens) 10 adults 5 presbyopes. We studied effect age pupil diameter (in cyclopleged...
Purpose To measure the longitudinal chromatic aberration in vivo using psychophysical and wavefront-sensing methods patients with bilateral implantation of monofocal intraocular lenses (IOLs) similar aspheric design but different materials (hydrophobic Podeye hydrophilic Poday). Setting Instituto de Optica, Consejo Superior Investigaciones Cientificas, Madrid, Spain. Design Prospective observational study. Methods Measurements were performed use (480 to 700 nm) 950 a custom-developed...
PURPOSE: To measure the longitudinal chromatic aberration (LCA) by both psychophysical methods and in vivo double-pass retinal imaging patients bilaterally implanted with trifocal diffractive intraocular lenses (IOLs). METHODS: Measurements were performed a polychromatic adaptive optics system provided supercontinuum laser, Hartmann-Shack wavefront sensor, deformable mirror, motorized Badal system, pupil monitoring channel, channel monochromatically illuminated stimuli. Ten (20 eyes)...
Abstract We present a new metric (Multifocal Acceptance Score, MAS-2EV) to evaluate vision with presbyopic corrections. The MAS-2EV is based on set of images representing natural visual scenes at day and night conditions projected in far near displays, stereo target. Subjects view score the through different binocular corrections (monofocal far; bifocal corrections; monovision modified monovision) administered soft contact lenses (in cyclopleged young subjects) or simultaneous simulator...
PurposeThe purpose of this study is to compare the binocular visual perception participants wearing multifocal contact lenses and these same lens designs viewed through a temporal multiplexing simulator.MethodsVisual performance perceived quality at various distances were obtained in 37 soft M−CLs SimVis Gekko programmed with lenses. In pilot (n = 10) was measured terms LogMAR acuity (VA) far (4 m), intermediate (64 cm) near (40 through-focus VA (TFVA) curves simulated M−CLs. follow-up 27),...
Scleral crosslinking may provide a way to prevent or treat myopia by stiffening scleral tissues. The ability measure the stiffness of tissues in situ pre and post would be useful but has not been established. Here, we tested feasibility optical coherence elastography (OCE) shear modulus evaluate impact on different posterior regions using ex vivo porcine eyes as model. From measured elastic wave speeds at 6 - 16 kHz, obtained out-of-plane value 0.71 ± 0.12 MPa (n = 20) for normal After...
Abstract Theimage formed by the eye's optics is inherently blurred aberrations specific to individual's eyes. We examined what extent judgments of perceived focus depend on total magnitude as opposed pattern blur introduced high order (HOA). An Adaptive Optics system was used simultaneously correct each subject's wave and display natural images simulated aberrations. To isolate effects magnitude, were pure symmetric defocus, subjects judged level defocus that subjectively appeared best...
PURPOSE: To measure the in vivo longitudinal chromatic aberration (LCA) from difference of focus (480 to 700 nm) using psychophysical methods patients bilaterally implanted with a hydrophobic trifocal intraocular lens (IOL). METHODS: Psychophysical best was measured both eyes at different wavelengths and three viewing distances (0.00, +1.75, +3.50 diopters [D]) custom-developed polychromatic adaptive optics set-up provided supercontinuum laser, Hartmann-Shack wavefront sensor, deformable...
Due to chromatic aberration, blue images are defocused when the eye is focused middle of visible spectrum, yet we normally not aware blur. The suffers from monochromatic aberrations which degrade optical quality all projected on retina. combination and additive these may interact improve image quality. Using Adaptive Optics, investigated visual effects correcting viewing polychromatic grayscale, green, images. Correcting eye's improved green degraded images, particularly in eyes with higher...
Visual simulators are useful tools to provide patients experience of multifocal vision prior treatment. In this study, commercially available center-near aspheric contact lenses (MCLs) low, medium, and high additions were mapped on a spatial light modulator (SLM) validated bench. Through focus visual acuity (TFVA) was measured in subjects through the SLM real MCLs eye. A correlation metric revealed statistically significant shape similarity between TFVA curves with simulated MCLs....
Visual simulators aim at evaluating vision with ophthalmic corrections prior to prescription or implantation of intraocular lenses (IOLs) in the patient's eye. In present study, we design, implementation, and validation a new IOL-in-cuvette channel an Adaptive Optics visual simulator, which provides alternative for pre-operative simulation IOLs. The IOL is projected on pupil's plane subject by using Rassow system. A second lens, compensates 20 D while other powers can be corrected Badal...
Diffractive multifocal intraocular lenses (IOLs) modulate chromatic aberration and reduce it at certain distances due to interactions between the refractive diffractive components. However, extent which computer modeling on bench measurements of IOL translate in patients implanted with these IOLs (MIOLs) is not yet fully understood. In this study, we compare difference focus longitudinal aberrations pseudophakic different designs (monofocal trifocal IOLs) materials (hydrophobic hydrophilic),...
The COVID pandemic is forcing the renewal of scientific conferences, offering opportunities to introduce technological and inclusive developments. Our analysis focuses on implementation practices for female early-career researchers in a virtual conference. This organization approach was applied XIII Spanish Optical Meeting (RNO2021), which also characterized by avatars interacting an online metaverse. effectiveness policies novel tools evaluated using participation data post-conference...
Convolved images are often used to simulate the effect of ocular aberrations on image quality, where retinal is simulated by convolving stimulus with point spread function derived from subject's aberrations. However, some studies have shown that convolved perceived far more degraded than same blurred optical defocus. We hypothesized positive interactions between monochromatic and chromatic in eye lost convolution process. To test this hypothesis, we evaluated visual quality natural optics...