A5084540610- Heart Rate Variability and Autonomic Control
- High Altitude and Hypoxia
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Multiple Sclerosis Research Studies
- Cardiovascular and exercise physiology
- EEG and Brain-Computer Interfaces
- Ultrasound and Hyperthermia Applications
- Non-Invasive Vital Sign Monitoring
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Functional Brain Connectivity Studies
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Hemoglobinopathies and Related Disorders
- Heart Failure Treatment and Management
- Liver Disease and Transplantation
- Olfactory and Sensory Function Studies
- Mental Health Research Topics
- Thermoregulation and physiological responses
- Neural dynamics and brain function
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cardiovascular Effects of Exercise
- Vanadium and Halogenation Chemistry
- MicroRNA in disease regulation
Medical University Plovdiv
2010-2024
Hôpital Raymond-Poincaré
2007
1. The impact of ventilatory efficiency on reduced exercise capacity and recovery oxygen kinetics has not been addressed in cirrhotic patients. aim the present study was to investigate performance patients with mild moderate liver cirrhosis (LC). 2. Nineteen male non-hypoxic LC (age 51.3 +/- 9.1 years; body mass index (BMI) 25.6 3.6 kg/m(2)) classified by Child-Pugh score as class A (n = 7) B 12) 19 age- BMI-matched controls participated study. Subjects undertook maximal incremental testing...
Purpose The purpose of this study is to establish the alterations in activity autonomic nervous system (ANS) via heart rate variability (HRV) subjects exposed 1 h exogenous hypoxia for 10 consecutive days. Methods Twelve healthy non-smoker males at mean age 29.8 ± 7.4 (mean SD) breathed hypoxic air delivered through hypoxicator (FiО 2 = 12.3% 1.5%) Pulse oximetry and electrocardiography were monitored during visit HRV was calculated entire 1-h period. Results Comparing last first, had higher...
The correlation between fatigue and cognitive performance in Multiple sclerosis (MS) is well reported, but the intimate mechanisms of impact on cognition are not fully defined yet. aim this study to investigate blood oxygen level dependent (BOLD) activations relapsing-remitting MS (RRMS) patients with without dysfunction cortical activations. Forty-two RRMS were enrolled study. Cognitive functioning was assessed by Symbol Digit Modalities Test (SDMT) Paced Serial Addition (PASAT). Cut –off...
Paced Auditory Serial Addition Test (PASAT) is used for assessment of information processing speed, attention, and working memory, which are the most frequently affected cognitive domains in multiple sclerosis (MS) patients, may be significantly by fatigue. However, effect fatigue mood on PASAT performance MS patients translationally validated fMRI has not been studied yet. The aim this study to investigate translational validity PASAT, using during a paced visual serial addition test...
Pharmacological treatment of depression is currently led by the trial and error principle mainly because lack reliable biomarkers. Earlier findings suggest that baseline alpha power asymmetry could differentiate between responders non-responders to specific antidepressants.The current study investigated quantitative electroencephalographic (QEEG) measures before early in as potential response predictors various antidepressants a naturalistic sample depressed patients. We were aiming at...
Continuous positive airway pressure (CPAP) improves autonomic activity in patients with chronic heart failure (CHF) and central sleep apnoea (CSA), but its effect on rate variability (HRV) during therapy has not been reported. We hypothesized that CPAP may decrease HRV, despite beneficial effects sympathetic overactivation, due to the expected stabilization of breathing. Sixty-seven CHF underwent polysomnography (PSG). Ten them presented CSA (age 66.1±8.5 years, apnoea-hypopnea index...
Cíl: Zjistit dynamiku autonomního nervového systému (ANS) pomocí variability srdeční frekvence (heart rate variability, HRV) během akutní expozice normobarické hypoxii a po ní, k níž dochází jednoho sezení podle protokolu intermitentního hypoxického tréninku.Materiál metody: Čtyřiadvacet zdravých mužů ve věku 28,0 ± 7,2 (průměr SD) vdechovalo dobu jedné hodiny hypoxický vzduch (inspirační koncentrace kyslíku [FiO2] 12,3 1,5 %) z generátoru (AltiPro 8850 Summit+, Altitude Tech,...
In Brief PURPOSE Standardized peak exercise perception score (SPEPS) is an index representing patient effort defined as SPEPS = Borg/METs, where Borg the CR-10 at maximal intensity and METs metabolic equivalents. The purpose of study was to assess validity in different groups examine its applicability for evaluation training outcomes. METHODS Patients (n 17) with chronic heart failure (CHF, New York Heart Association [NYHA] II III functional class; ejection fraction= 31 ± 14%), 16 patients...
The aim of our study was to compare the autonomic nervous system (ANS) activity between young "healthy" male smokers and non-smokers via method heart rate variability (HRV).Pulse oximetry, blood pressure, time frequency domain non-linear HRV parameters were measured in 21 healthy non-smoker males aged 28.0 ± 7.4 (mean±SD) fourteen smoker 28.1±4.3 with 9.2±5.6 pack-years resting supine position.Smokers instructed refrain from smoking at least 2 hours before test.There no difference nonsmoker,...
<b>Introduction:</b> Chronic insomnia disorder (CID) offers significant diagnostic challenges due to the marked heterogeneity among patients based on type of and average sleep duration. <b>Aims:</b> The present study aims investigate expression 10 miRNAs in plasma white blood cells (WBCs) chronic healthy controls. <b>Methods:</b> Polysomnography was performed 21 CID 11 controls (HC) rule out a concomitant disorder. According analysis diaries patients, they were divided into short (SD) normal...
The aim of this study was to compare the activity autonomic nervous system (ANS) using heart rate variability (HRV) in 'healthy' young smokers and non-smokers before, during after exogenous hypoxic provocation.Twenty-one healthy non-smoking males aged 28.0 ± 7.4 years (mean SD) 14 smoking 28.1 4.3 with 9.2 5.6 pack-years were subjected one-hour exposure (FiO2 = 12.3 1.5%) via a hypoxicator. HRV data derived Kubios HRV, Finland software by analysing pre-hypoxic, post-hypoxic periods.Standard...
<b>Background:</b> Measurement of exhaled breath temperature (EBT) has been used to evaluate inflammation in the respiratory system. It proven that vasodilation airways corresponds higher EBT, but whether vasocinstriction decreases is not sufficiently studied. <b>Aim:</b> To assess effect bronchial vasoconstriction on EBT. <b>Methods:</b> Twelve adults (6 males) were included, half them smokers, mean age 31.2±5.9. We a fast responsive thermal sensor (1kHz sampling rate) placed mouthpiece...
<b>Introduction:</b> Exogenous hypoxia changes the activity of autonomic nervous system which could be diminished in patients with dysautonomia. <b>Aim:</b> To assess effect smoking on parasympathetic reactivation via heart rate variability (HRV) after exogenous hypoxic exposure. <b>Material and methods:</b> Twenty-one healthy non-smoking males aged 28.0±7.4 (mean±SD) fourteen male smokers 28.1±4.3 9.2±5.6 pack-years were subjected to one-hour exposure (FiO<sub>2</sub>=12.3±1.5%) hypoxicator...