Hao Wu

ORCID: 0000-0003-1320-4603
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About
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Research Areas
  • Ruminant Nutrition and Digestive Physiology
  • Reproductive Physiology in Livestock
  • Animal Nutrition and Physiology
  • Meat and Animal Product Quality
  • Gout, Hyperuricemia, Uric Acid
  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Turfgrass Adaptation and Management
  • Genetic and phenotypic traits in livestock
  • Food composition and properties
  • Liver Disease Diagnosis and Treatment
  • Effects of Environmental Stressors on Livestock
  • Muscle metabolism and nutrition
  • Reproductive Biology and Fertility
  • Listeria monocytogenes in Food Safety
  • Plant and animal studies
  • Anaerobic Digestion and Biogas Production
  • Fossil Insects in Amber
  • Microbial Inactivation Methods
  • Agriculture, Soil, Plant Science
  • Biofuel production and bioconversion
  • Magnetic and Electromagnetic Effects
  • Clostridium difficile and Clostridium perfringens research
  • Birth, Development, and Health
  • Carbon and Quantum Dots Applications

China Agricultural University
2016-2025

Peking University First Hospital
2025

Peking University
2025

China National Rice Research Institute
2023-2025

Tianjin University
2021-2025

Dalian Medical University
2018-2025

First Affiliated Hospital of Dalian Medical University
2018-2025

Shaoxing University
2025

Nanjing Medical University
2022-2024

South China Agricultural University
2023

Current knowledge about the relationships between ruminal bacterial communities and metabolite profiles in yak rumen is limited. This due to differences nutritional metabolic features other ordinary cattle combined with difficulties associated farm-based research a lack of technical guidance. A comprehensive analysis composition alterations metabolites required advance development modern husbandry. In current study, we characterized effect feed type on fluid microbiota using 16S rRNA gene...

10.3389/fmicb.2019.01116 article EN cc-by Frontiers in Microbiology 2019-05-22

Changes in dietary composition affect the rumen microbiota ruminants. However, information on effects of concentrate-to-forage ratio changes yak bacteria and metabolites is limited. This study characterized effect three different ratios (50:50, C50 group; 65:35, C65 80:20, C80 group) fluid using 16S rRNA gene sequencing liquid chromatography-mass spectrometry (LC-MS) analyses. Rumen fermentation parameters abundance were affected by ratio, there was a strong correlation between them. At...

10.3389/fnut.2022.927206 article EN cc-by Frontiers in Nutrition 2022-07-14

Feed cost is the greatest expense during cattle production; therefore, reducing it critical to increasing producer profits. In ruminants, microbial population important nutrient digestion and absorption in rumen. The objective of this study was investigate relationships among rumen bacteria, metabolites, residual feed intake (RFI) phenotype beef cattle. Twelve Angus heifers were selected be sampled divided into high RFI (HRFI; n = 6) group low (LRFI; according their classification determined...

10.3389/fvets.2022.812861 article EN cc-by Frontiers in Veterinary Science 2022-03-25

Chestnut is widely cultivated and has high nutritional value due to its richness in polysaccharides. In order improve the antioxidant activity of chestnut polysaccharide, polysaccharide (CP) was extracted by ultrasonic-assisted water extraction alcohol precipitation purified cellulose DEAE-52 exchange Sephadex G-100 chromatography this study. CP isolates were characterized I2-KI reaction, three-strand helical structure analysis, infrared spectrum nuclear magnetic resonance detection. The...

10.3389/fnut.2022.1054601 article EN cc-by Frontiers in Nutrition 2023-01-18

Guanidinoacetic acid (GAA) functions as a precursor for creatine synthesis in the animal body, and maintaining ample reserves is essential fostering rapid growth. This study aimed to explore impact of GAA supplementation on growth performance, rumen fermentation, blood indices, nutrient digestion, nitrogen metabolism Angus steers through two experiments: feeding experiment (Experiment 1) digestive 2). In Experiment 1, thirty-six (485.64 ± 39.41 kg BW) at 16 months age were randomly assigned...

10.3390/ani14030401 article EN cc-by Animals 2024-01-26

Grain size is an important determinant of grain yield in rice. Although dozens genes have been reported, the molecular mechanism controlling remains to be further elucidated. Here, we report cloning and characterization GR5 (GRAIN ROUND 5), which allelic SMOS1/SHB/RLA1/NGR5 encodes a member AP2 transcription factor. acts as activator determines by influencing cell proliferation expansion. We demonstrated that physically interacts with five Gγ subunit proteins including RGG1, RGG2, DEP1, GS3...

10.1016/j.xplc.2023.100673 article EN cc-by-nc-nd Plant Communications 2023-08-18

Methionine plays a vital role in protein synthesis, and regulation of antioxidant response ruminants. This study aimed to assess the effects dietary supplementation with N-acetyl-l-methionine (NALM), which serves source rumen-protected methionine, on growth performance, carcass traits, meat quality, oxidative stability. Sixty Angus heifers (initial body weight = 408 ± 51.2 kg, 15-18 months) were stratified by randomly assigned four treatments: control group (0% NALM), experimental groups...

10.1016/j.meatsci.2024.109499 article EN cc-by-nc-nd Meat Science 2024-03-20

Exploring the compositional characteristics of rumen eukaryotic community can expand our understanding their role in function and feed efficiency. In this study, we applied metatranscriptomics to characterize active (protozoa fungi) beef cattle (n = 48) three breeds [Angus (AN), Charolais (CH), Kinsella Composite (KC)] with divergent residual intake (RFI). The composition microbiota was evaluated based on enriched 18S rRNAs from metatranscriptomic datasets. At phylum level, a total 4...

10.3389/fmicb.2020.00367 article EN cc-by Frontiers in Microbiology 2020-03-13

The gastrointestinal tract (GIT) contains complex microbial communities and plays an essential role in the overall health of host. Previous studies beef cattle feed efficiency have primarily concentrated on ruminal microbiota because it a key energy production nutrient supply Although small intestine is important site post-ruminal digestion absorption nutrients, only few explored relationship between populations efficiency. Moreover, variations GIT metabolites contribute to differences...

10.3389/fmicb.2022.862151 article EN cc-by Frontiers in Microbiology 2022-04-21

The role and underlying mechanism of liver macrophages their derived miR-155-5p in hepatic lymphangiogenesis fibrosis remain unclear. Here, we investigated the by which were involved during cirrhosis.In vivo, lymphatic vessel expansion was evaluated; macrophage subsets, proportion peripherally-derived expressions CCL25, MCP-1, VAP-1 MAdCAM-1 documented; peripheral blood detected. In vitro, with overexpression inhibition used to clarify effect on regulation polarization possible signalling...

10.1177/09603271221141695 article EN cc-by-nc Human & Experimental Toxicology 2023-01-18

Yak ( Bos grunniens ) is an important economic animal species on the Qinghai-Tibet Plateau. Yaks grazed in cold season often suffer from nutritional stress, resulting low production performance. This situation can be improved by properly feeding grazing yaks season; however, there still little information about effect of different levels intestinal microflora and metabolites yaks. Therefore, this study aimed to explore doses concentrate supplements rumen bacterial communities during season....

10.3389/fmicb.2023.1247251 article EN cc-by Frontiers in Microbiology 2023-08-28

Summary Panicle size and grain number are important agronomic traits that determine yield in rice. However, the underlying mechanism regulating panicle remains largely unknown. Here, we report GS2 plays an role architecture. The RNAi of GS2™ (target site mutation, TM) produced erect dense with increased primary secondary branches per panicle, whereas overexpression showed longer panicles fewer grains than wild‐type. directly binds to GCCA motif significantly enhances transcriptional...

10.1111/nph.20412 article EN cc-by New Phytologist 2025-01-31

This study aimed to investigate the effects of cellulase, protease, and starch on fermentation quality, in vitro digestibility, microbial community mulberry leaf silage after 30d ensiling. Mulberry leaves (376 g/kg dry matter (DM)) were ensiled with four experimental treatments: i) CON, no additives; ii) CEL, added cellulase (120 U/g fresh [FM]); iii) CPR, FM) protease (50 FM); iv) CPS, FM), (2% FM). All treatments additives improved showing higher DM (353 ~ 378 vs. 341 DM), lactic acid (LA)...

10.3389/fpls.2025.1517529 article EN cc-by Frontiers in Plant Science 2025-02-18

Akkermansia muciniphila (A. muciniphila), known as a next-generation probiotic, has been widely recognized for its beneficial effects in various metabolic diseases. While there is not much research whether live or pasteurized A. different on intestinal health. In the present study, strain of was isolated from healthy individuals, with and named Timepie001 Timepie001+, respectively. They were administered to dextran sulfate sodium-induced ulcerative colitis mice investigate their influences...

10.3389/fmicb.2025.1542522 article EN cc-by Frontiers in Microbiology 2025-02-19

In vitro rumen gas production experiment was conducted with 57 kinds of feedstuff, which were categorized into energy feed, protein and roughage, collected within China. Eight mathematical models employed to describe the kinetics in production. The results found that for feeds, roughages, respectively, Michaelis–Menten (MM) or Logistic-Exponential lag (LEL), MM, Mitscherlich (MIT) exhibited highest shown no significant difference compared coefficient determination (R2) (P < 0.05) all...

10.1038/s41598-025-90189-8 article EN cc-by-nc-nd Scientific Reports 2025-02-24
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