A5066565710- Comparative International Legal Studies
- Family and Matrimonial Law
- Human Rights and Immigration
- Legal processes and jurisprudence
- Finance, Taxation, and Governance
- Data Privacy and Cybersecurity
- Ethics and bioethics in healthcare
- Comparative constitutional jurisprudence studies
- Taxation and Legal Issues
- European and International Contract Law
- Law, AI, and Intellectual Property
- Labor Law and Work Dynamics
- Administrative Law and Governance
- Law, Ethics, and AI Impact
- Conflict of Laws and Jurisdiction
- CRISPR and Genetic Engineering
- Classical Studies and Legal History
- Social Sciences and Policies
- Historical Studies in Latin America
- Virus-based gene therapy research
- Corporate Governance and Law
- Animal Law and Welfare
- Digitalization, Law, and Regulation
- Artificial Intelligence in Law
- Copyright and Intellectual Property
Instituto de Investigación de Enfermedades Raras
2024
Centre for Biomedical Network Research on Rare Diseases
2023-2024
Instituto de Salud Carlos III
2024
Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas
2023-2024
Hospital Universitario Fundación Jiménez Díaz
2023-2024
Universidad Autónoma de Madrid
2024
Centro de Investigación Biomédica en Red
2023
Universitat Autònoma de Barcelona
2011-2022
Fundacion Centro De Investigacion De Enfermedades Neurologicas
2020
Instituto Conmemorativo Gorgas de Estudios de la Salud
2020
The alphaviruses Chikungunya (CHIKV), Mayaro (MAYV), Una (UNAV), and the flavivirus Zika (ZIKV) are emerging or re-emerging arboviruses which responsible for frequent epidemic outbreaks. Despite large impact of these on health systems, there no approved vaccines treatments to fight infections. As a consequence, is an urgent need discover new antiviral drugs. Natural products rich source compounds with distinct biological activities, including properties. Thus, we aimed explore potential...
This study lays the groundwork for future lentivirus-mediated gene therapy in patients with Diamond Blackfan anemia (DBA) caused by mutations ribosomal protein S19 (RPS19), showing evidence of a new safe and effective therapy. The data show that, unlike Fanconi (FA), hematopoietic stem cell (HSC) reservoir DBA was not significantly reduced, suggesting that collection these cells should constitute remarkable restriction Subsequently, 2 clinically applicable lentiviral vectors were developed....
Clinical trials have shown that lentiviral-mediated gene therapy can ameliorate bone marrow failure (BMF) in nonconditioned Fanconi anemia (FA) patients resulting from the proliferative advantage of corrected FA hematopoietic stem and progenitor cells (HSPC). However, it is not yet known if revert affected molecular pathways diseased HSPC. Single-cell RNA sequencing was performed chimeric populations uncorrected HSPC co-existing BM therapy-treated patients. Our study demonstrates reverts...
The manufacturer's liability for defective products has remained almost unmodified since 1985 when Directive 85/374/EEC (=PLD) was enacted. Perhaps new technology based on artificial intelligence (=AI) could bring about a turning point in the regulation if concepts such as "product" and "defect" or aspects "grounds of liability", so-called "development risks defense", "solidarity" are...
We need legal services, but not always and, in any case, lawyers. There are other companies on the market, real business structures, which represent a highly recommended alternative to traditional law firms. These companies, mostly known by English term "LegalTech" startups, offer their "products" final consumer. In this sense, they able facilitate access to, for example, writing of documents, presentation claims or possibility finding suitable lawyer consumer's case free at very low cost....
This paper deals with an important question: Why children and young people disabilities are almost absent from the debate about rights, specially, participation rights? Figures show that represent, in our society, a minority within another minority, of "children people". In order to answer this question, adults should change how communicate them reach major knowledge regarding new means communication, above all, when technology is involved. New technologies could facilitate accessibility...
Abstract Fanconi anemia (FA) is a rare genetic disease characterized by high phenotypic and genotypic heterogeneity, extreme chromosome fragility. To better understand the natural history of FA, identify risk prognostic factors, develop novel therapeutic strategies, Spanish Registry Patients with FA collects data on clinical features, fragility, subtypes, DNA sequencing informed consent participating individuals. In this article, we describe evolution 227 patients followed up for to 30...
La publicación el 28 de septiembre 2022 dos Propuestas Directiva que abordan aspectos relacionados con los daños ocasionados por sistemas inteligencia artificial dan pie a interesantes y controvertidas cuestiones. En este trabajo tras exponer comunes ambas establecer también las diferencias, me adentro, en primer lugar, estudio la Propuesta responsabilidad civil extracontractual derivada puesta circulación o servicio mercado para concluir, entre otras consideraciones, se alivia muy poco -si...
Step-families are included within the concept of “family” used by both Art. 8 Rome Convention for protection Human Rights and Fundamental Freedoms 7 European Charter 2010. According to OECD EUROSTAT figures children that living in step-families between 12 years old, is, they could be considered as preadolescents or some cases adolescents at all. Thus, individuals with a certain grade maturity allow them form their own views express them. Today, there is an inevitable link family children’s...