A5077686886- Pediatric Hepatobiliary Diseases and Treatments
- Liver Disease and Transplantation
- Liver physiology and pathology
- Drug Transport and Resistance Mechanisms
- Liver Diseases and Immunity
- Drug-Induced Hepatotoxicity and Protection
- Digestive system and related health
- Pancreatitis Pathology and Treatment
Universidad Autónoma Metropolitana
2019-2022
Instituto Nacional de Cardiología
2022
Instituto Nacional de Cardiologia
2022
he prevalence of cholestasis has been increasing in recent years; The excretion bile acids via basolateral demonstrated to prevent the excessive accumulation hepatocyte, and liver-intestine axis seen affected by enterohepatic circulation deregulation. epithelial permeability loss caused tight junction ruptures leads inflammation reactive oxygen species (ROS) production. hepatocyte growth factor is an essential cellular redox regulator repair factor; it reported its relevance intestinal...
Aim: Cholestasis remains a partially characterized disease. Evidence has been gained that it is systemic disease begins in the liver but significantly impacts other organs and systems such as kidney, heart, intestine, among others. One of primary damage mechanisms generation reactive oxygen species (ROS), which eventually leads to oxidative stress, impacting canalicular morphology actin cytoskeleton changes could worsen problem. These characteristics are also observed kidney intestine. The...