John D. Loeser

ORCID: 0000-0003-1355-0952
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Musculoskeletal pain and rehabilitation
  • Spine and Intervertebral Disc Pathology
  • Pain Mechanisms and Treatments
  • Pain Management and Placebo Effect
  • Pain Management and Opioid Use
  • Pain Management and Treatment
  • Anesthesia and Pain Management
  • Cerebrospinal fluid and hydrocephalus
  • Pediatric Pain Management Techniques
  • Spinal Dysraphism and Malformations
  • Botulinum Toxin and Related Neurological Disorders
  • Gender, Labor, and Family Dynamics
  • Trigeminal Neuralgia and Treatments
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Spinal Fractures and Fixation Techniques
  • Opioid Use Disorder Treatment
  • History of Medical Practice
  • Fetal and Pediatric Neurological Disorders
  • Craniofacial Disorders and Treatments
  • Spinal Cord Injury Research
  • Stroke Rehabilitation and Recovery
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Nerve Injury and Rehabilitation
  • Cleft Lip and Palate Research

University of Washington
2014-2024

Neurological Surgery
2013-2024

World Bank Group
2020

GTx (United States)
2018

Pain and Rehabilitation Medicine
2017

Seattle University
1979-2016

University of Birmingham
2013

Klinik und Poliklinik für Neurologie
2012

University of Lübeck
2012

Danish Pain Research Center
2012

Jensen, Troels S.*,1; Baron, Ralf2; Haanpää, Maija3; Kalso, Eija4; Loeser, John D.5; Rice, Andrew S.C.6; Treede, Rolf-Detlef7 Author Information

10.1016/j.pain.2011.06.017 article EN Pain 2011-07-23

We examined the rates of postoperative complications and mortality, as recorded in a hospital discharge registry for State Washington years 1986 through 1988, patients who had an operation on lumbar spine. When malignant lesion, infection, or fracture are excluded, there were 18,122 hospitalizations procedures spine, 84 per cent which involved herniated disc spinal stenosis. The morbidity mortality during hospitalization, well charges, increased with ages patients. rate was 18 seventy-five...

10.2106/00004623-199274040-00009 article EN Journal of Bone and Joint Surgery 1992-04-01

In Brief Study Design. Clinical practice guideline. Objective. To develop evidence-based recommendations on use of interventional diagnostic tests and therapies, surgeries, interdisciplinary rehabilitation for low back pain any duration, with or without leg pain. Summary Background Data. Management patients persistent disabling remains a clinical challenge. A number therapies surgery are available their is increasing, but in some cases utility uncertain controversial. Interdisciplinary has...

10.1097/brs.0b013e3181a1390d article EN Spine 2009-05-01

The radicular pain of sciatica was ascribed by Mixter and Barr to compression the spinal root a herniated intervertebral disc. It assumed that produced prolonged firing in injured sensory fibers led perceived peripheral distribution those fibers. This concept has been challenged on basis acute nerve neuropathies are usually painless. Furthermore, animal experiments have rarely shown more than several seconds repetitive acutely compressed nerves or roots. suggested "radicular pain" is...

10.1016/0304-3959(77)90033-1 article EN Pain 1977-02-01

✓ A total of 93 patients with intractable spasticity due to either spinal cord injury (59 cases), multiple sclerosis (31 or other pathology (three cases) were entered into a randomized double-blind placebocontrolled screening protocol intrathecal baclofen test injections. Of the 88 who responded an bolus 50, 75, 100 µg baclofen, 75 underwent implantation programmable pump system for chronic therapy. Patients followed 5 41 months after surgery (mean 19 months). No deaths new permanent...

10.3171/jns.1993.78.2.0226 article EN Journal of neurosurgery 1993-02-01

aDepartment of Psychology, McGill University, Montreal, Que.Canada bDepartment Neurological Surgery, University Washington, School Medicine, Seattle, Wash. 98195 U.S.A. Accepted May 24, 1977.

10.1016/0304-3959(77)90133-6 article EN Pain 1977-10-01

T HE study of focal cortical epilepsy has led us to the belief that epileptic neurons are partially deafferentY The validity this hypothesis been demonstrated in cat spinal cord where rhizotomy or hemi-cordotomy result neuronal firing patterns similar those seen an focus. 1 Other work our laboratories shown certain epileptogenic agents, when injected into cat, can produce unusual sensory states suggestive pain and typical epilepsy? It is many central occur after nerve injury may be due...

10.3171/jns.1968.29.1.0048 article EN Journal of neurosurgery 1968-07-01

For many medical professionals dealing with patients persistent pain following spine surgery, the term Failed back surgery syndrome (FBSS) as a diagnostic label is inadequate, misleading, and potentially troublesome. It misrepresents causation. Alternative terms have been suggested, but none has replaced FBSS. The International Association for Study of Pain (IASP) published revised classification chronic pain, part new Classification Diseases (ICD-11), which accepted by World Health...

10.1093/pm/pnab015 article EN cc-by-nc Pain Medicine 2021-01-19

The authors have routinely performed primary autologous cranioplasty to repair skull defects after decompressive craniectomy. high rates of subsequent bone resorption occurring in children prompted this study.In an institutional review, the identified 40 (32 male and eight female) adolescents ranging from 4 months 19 years age whom was defect surface area ranged 14 147 cm2. In all cases, fresh frozen at time decompression. Symptomatic subsequently occurred 20 (50%) reoperation required....

10.3171/ped.2004.100.2.0163 article EN Journal of Neurosurgery Pediatrics 2004-02-01

Low back pain is common, but a herniated intervertebral disk the cause in only small percentage of cases. Most symptomatic herniations result clinical manifestations (pain, reflex loss, muscle weakness) that resolve with conservative therapy, and 5% to 10% patients require surgery. Sciatica usually first clue herniation, sciatica may be mimicked by other disorders radiating pain. Because more than 95% lumbar occur at L4-5 or L5-S1 levels, physical examination should focus on abnormalities L5...

10.7326/0003-4819-112-8-598 article EN Annals of Internal Medicine 1990-04-15

Regional variations in lumbar spinal fusion rates suggest a poor consensus on surgical indications. Therefore, complications, costs, and reoperation were compared for elderly patients undergoing surgery with or without fusion. Subjects Medicare recipients who underwent 1985, 4 years of subsequent follow-up. There 27,111 eligible patients, whom 5.6% had fusions. Mean age was 72 years. Patients complication rate 1.9 times greater than those The blood transfusion 5.8 greater, nursing home...

10.1097/00007632-199318110-00010 article EN Spine 1993-09-01
Coming Soon ...