A5010417936- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Pain Management and Opioid Use
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Management and Treatment
- Spinal Hematomas and Complications
- Pain Mechanisms and Treatments
- Nausea and vomiting management
- Anesthesia and Sedative Agents
- Pain Management and Placebo Effect
- Opioid Use Disorder Treatment
- Pediatric Pain Management Techniques
- Myofascial pain diagnosis and treatment
- Dental Anxiety and Anesthesia Techniques
- Venous Thromboembolism Diagnosis and Management
- Shoulder Injury and Treatment
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cardiac Arrest and Resuscitation
- Anesthesia and Neurotoxicity Research
- Intraocular Surgery and Lenses
- Botulinum Toxin and Related Neurological Disorders
- Nerve Injury and Rehabilitation
- Peripheral Neuropathies and Disorders
- Sympathectomy and Hyperhidrosis Treatments
Cleveland Clinic
2015-2025
Karolinska Institutet
2023-2024
Karolinska University Hospital
2023-2024
Stanford University
2019
Novem (Netherlands)
2019
Pain Management Institute
2018
Institut Mines-Télécom Business School
2018
American Society of Anesthesiologists
2011-2017
Virginia Mason Medical Center
2016-2017
Accreditation Council for Graduate Medical Education
2017
The actual incidence of neurologic dysfunction resulting from hemorrhagic complications associated with neuraxial blockade is unknown. Although the cited in literature estimated to be less than 1 150,000 epidural and 220,000 spinal anesthetics, recent epidemiologic surveys suggest that frequency increasing may as high 3000 some patient populations.Overall, risk clinically significant bleeding increase age,associated abnormalities cord or vertebral column, presence an underlying coagulopathy,...
In Brief Study Design. Clinical practice guideline. Objective. To develop evidence-based recommendations on use of interventional diagnostic tests and therapies, surgeries, interdisciplinary rehabilitation for low back pain any duration, with or without leg pain. Summary Background Data. Management patients persistent disabling remains a clinical challenge. A number therapies surgery are available their is increasing, but in some cases utility uncertain controversial. Interdisciplinary has...
Abstract Patients with chronic lymphocytic leukemia (CLL) progressing on ibrutinib constitute an unmet need. Though Bruton tyrosine kinase (BTK) and PLCG2 mutations are associated resistance, their frequency relevance to progression not fully understood. In this multicenter retrospective observational study, we analyzed 98 patients CLL (49 relapsing after initial response 49 still responding ≥1 year of continuous treatment) using a next-generation sequencing (NGS) panel (1% sensitivity)...
General anesthesia (GA) and brachial plexus block have been used successfully for surgery on the upper extremities. Controversy exists as to which method is more suitable in outpatients undergoing hand wrist surgery. The authors hypothesized that infraclavicular (INB) performed with a short-acting local anesthetic would result shorter time discharge home compared "fast-track" GA.After obtaining written informed consent, 52 patients (aged 18-65 yr, American Society of Anesthesiologists...
Abstract Background Various multimodal analgesic approaches have been proposed for spine surgery. The authors evaluated the effect of using a combination four nonopioid analgesics versus placebo on Quality Recovery, postoperative opioid consumption, and pain scores. Methods Adults having multilevel surgery who were at high risk double-blind randomized to placebos or single preoperative oral doses acetaminophen 1,000 mg gabapentin 600 mg, an infusion ketamine 5 µg/kg/min throughout surgery,...
The Acute Pain Summit 2005 was convened to critically examine the perceptions of physicians about current methods used control postoperative pain and compare those with available scientific evidence. Clinicians expertise in treatment postsurgical were asked evaluate 10 practice-based statements. statements written reflect areas within field acute-pain management, where significant questions remain regarding everyday practice. Each statement made a specific claim usefulness therapy (eg, PCA...
( Anesthesiology. 2016;124:535–552) Practice guidelines are systematically developed recommendations that enable the practitioner and patient to make informed health care decisions. They may be adopted, modified, or rejected based on clinical needs constraints, subject revision as necessitated by advancement of medical knowledge, technology, practice. This review is an update American Society Anesthesiologists for prevention, detection, management respiratory depression associated with...
Abstract Background Lumbar spinal stenosis ( LSS ) can lead to compression of neural elements and manifest as low back leg pain. has traditionally been treated with a variety conservative (pain medications, physical therapy, epidural injections) invasive (surgical decompression) options. Recently, several minimally procedures have expanded the treatment Methods The Spinal Stenosis Consensus Group convened evaluate peer‐reviewed literature basis for making spine MIST recommendations. Eleven...
Chemotherapy-induced peripheral neuropathy (CIPN) is a painful and debilitating side effect of cancer chemotherapy with an unclear pathogenesis. Consequently, the available therapies for this neuropathic pain syndrome are inadequate, leading to significantly reduced quality life in many patients. Complement, key component innate immune system, has been associated neuroinflammation, potentially important trigger some types pain. However, role complement CIPN remains unclear. To address issue,...
Significant knowledge gaps exist in the perioperative pain management of patients with a history chronic pain, substance use disorder, and/or opioid tolerance as highlighted US Health and Human Services Pain Management Best Practices Inter-Agency Task Force 2019 report. The report emphasized challenges caring for these populations need multidisciplinary care comprehensive approach. Such requires stakeholder alignment across multiple specialties settings. With intention codifying this into...
<h3>Background and Objectives</h3> Postoperative pain is the expected but nonetheless undesirable byproduct of all surgical procedures. Humanitarian concerns recent quasi-governmental regulations have heightened awareness about importance treating postoperative pain. This guideline builds upon foundation created by Agency for Health Care Policy Research published in 1993, highlights changes that occurred over past 10 years, makes recommendations based on current scientific evidence. In...
<h3>Background and Objectives</h3> The Anesthesiology Review Committee of the Accreditation Council for Graduate Medical Education sets core requirements residency program accreditation. We periodically report analyze US anesthesiology residents9 training experience in regional anesthesia pain medicine. <h3>Methods</h3> Resident caseload, procedure, medicine evaluation data were aggregated resident cohort who graduated 2015. These analyzed present-day compared with previous reports from...
Evaluation of burn pain and its successful treatment has proven challenging for all staff who care patients. As relief is important full physical psychological recovery, accurate assessment essential. The authors sought to prospectively evaluate two previously validated scales, the Critical Care Pain Observation Tool (CCPOT) Adult Nonverbal Scale (ANVS), in our population compare them with patients' reports pain. Both scales include nonverbal behaviors that are numerically scored can be used...
Complex regional pain syndrome type 1 (CRPS-I) remains one of the most clinically challenging neuropathic syndromes and its mechanism has not been fully characterized. Cannabinoid receptor 2 (CB2) emerged as a promising target for treating different syndromes. In models, activated microglia expressing CB2 receptors are seen in spinal cord. Chemokine fractalkine (CX3CR1) plays substantial role microglial activation neuroinflammation. We hypothesized that agonist could modulate...
Abstract Editor’s Perspective What We Already Know about This Topic Article Tells Us That Is New Background Sympathetic dysfunction may be present in complex regional pain syndrome, and sympathetic blocks are routinely performed practice. To investigate the therapeutic predictive values of blocks, authors test hypotheses that provide analgesic effects associated with temperature differences between two extremities before after predict success (defined as achieving more than 50% reduction)...