A5018056347- Bone fractures and treatments
- Bone health and treatments
- Prosthetics and Rehabilitation Robotics
- Total Knee Arthroplasty Outcomes
- Bone health and osteoporosis research
- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- Muscle activation and electromyography studies
- Orthopaedic implants and arthroplasty
- Orthopedic Surgery and Rehabilitation
- Inflammatory mediators and NSAID effects
- Chemokine receptors and signaling
- Musculoskeletal Disorders and Rehabilitation
- Medical and Biological Sciences
- Bone Metabolism and Diseases
Rutgers, The State University of New Jersey
2020-2024
Rutgers New Jersey Medical School
2023-2024
John Wiley & Sons (United States)
2021
Periostin and osteopontin are matricellular proteins abundantly expressed in bone fracture callus. Null mutation of either the periostin ( Postn ) gene or Spp1 can impair healing. However, cell molecular pathways affected by loss POSTN SPP1 which lead to impaired healing not well understood. To identify potential pathways, a detailed radiological, histological, immunohistochemical analysis femur -null KO), normal (WT) mice was performed. Apparent changes specific protein levels identified...
Abstract The effects of naproxen, a nonsteroidal anti‐inflammatory drug (NSAID), on articular cartilage degeneration in female Sprague–Dawley rats was examined. Osteoarthritis (OA) induced by destabilization the medial meniscus (DMM) each knee. Rats were treated with acetaminophen (60 mg/kg), naproxen (8 or 1% carboxymethylcellulose (placebo) oral gavage twice daily for 3 weeks, beginning 2 weeks after surgery. OA severity assessed histological Research Society International (OARSI) scoring...
<sec> <title>BACKGROUND</title> Relative motion between the residual limb and socket in individuals with transtibial loss can lead to substantial consequences that limit mobility. Although assessments of relative have been performed, there remains a gap understanding complex mechanics limb-socket interface during dynamic activities limits ability improve design. However, stereo x-ray (DSX) is an advanced imaging technology quantify 3D bone movement skin deformation inside activities. </sec>...
Relative motion between the residual limb and socket in individuals with transtibial loss can lead to substantial consequences that limit mobility. Although assessments of relative have been performed, there remains a gap understanding complex mechanics limb-socket interface during dynamic activities limits ability improve design. However, stereo x-ray (DSX) is an advanced imaging technology quantify 3D bone movement skin deformation inside activities.
Estimating the mechanical properties of bone in vivo without destructive testing would be useful for research and clinical orthopedic applications. Micro-computerized tomography (μCT) imaging can provide quantitative, high-resolution 3D representations morphology is generally basis from which are non-destructively estimated. The goal this study was to develop metrics using qualitative quantitative aspects microarchitecture derived μCT estimate integrity fracture calluses. Mechanical data...
Abstract Shortcomings of fixation have been reported as a source graft failure in anterior cruciate ligament (ACL) reconstruction. While interference screws long used devices for ACL reconstruction, they are not without complications. Previous studies highlighted the use bone void filler method; however, no biomechanical comparisons using soft tissue grafts with exist to our knowledge. The purpose this study is evaluate strength calcium phosphate cement compared screw an reconstruction...