A5054445837- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Atherosclerosis and Cardiovascular Diseases
- Cardiac tumors and thrombi
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Cardiac Health and Mental Health
- Coronary Artery Anomalies
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Issues in Pregnancy
- Cardiovascular and Diving-Related Complications
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Acute Myocardial Infarction Research
- Lipoproteins and Cardiovascular Health
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Disease and Adiposity
- Sarcoma Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrhythmias and Treatments
- Takotsubo Cardiomyopathy and Associated Phenomena
- Adrenal Hormones and Disorders
- Mechanical Circulatory Support Devices
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2023
Medical University of Vienna
2023
Agostino Gemelli University Polyclinic
2015-2023
Università Cattolica del Sacro Cuore
2003-2022
University of the Sacred Heart
2016
Catholic University of America
2008-2015
C-reactive protein (CRP) plasma levels have been associated with short- and long-term occurrence of coronary events. We investigated whether circulating inflammatory cell responsiveness to low-grade stimuli could contribute the reported association between CRP events.We studied 32 patients unstable angina who were followed for 24 months free symptoms 6 (group 1): 19 had persistently high (>0.3 mg/dL) 1A); 13 normal 1B). During follow-up, 12 (63%) group 1A but no 1B developed an infarction or...
Abstract Understanding and managing hospital Organizational Readiness to Change is a key topic with strong practical implications on society worldwide. This study provides, through scoping literature review, framework aimed at creating road map for managers who are implementing strategic processes of change. Ideally, the should act as check-list proactively detect those items that likely impede successful 146 were identified clustered into 9 domains. Finally, although built setting, similar...
Primary heart sarcomas are exceedingly rare tumors. Among primary cardiac sarcomas, synovial sarcoma is one of the rarest, involving cavities or pericardium. Two cases presented with clinical course and therapy. Both were treated surgery chemo/radiotherapy. Interestingly, patient, a 52-year-old male an intracardiac sarcoma, undergone SynCardia total artificial implantation, but died for multiple pulmonary metastases waiting transplantation. Complete surgical resection gold standard therapy,...
best QRS shortening among those allowed by quadripolar lead can result in a better response to CRT compared with use of traditional bipolar lead. Methods Study PopulationFrom January 2010 2012, 43 consecutive patients (mean age 69±9 years; 37 male), referred our Center for CRT, were prospectively enrolled and randomized using computergenerated table random numbers.Of them, 23 67±11 21 male) implanted LV (group 1) 20 71±6 16 2).Patients preexisting pacemaker or ICD device excluded.Indications...
Inflammation has been shown to play a pivotal role in ischemic heart disease, particular unstable angina. The instability that characterizes this syndrome is related the waxing and waning of stimuli, especially thrombotic ones. Angiographically autoptically severity atherosclerotic background angina does not differ from chronic stable angina, but former mural thrombi are often found coronary plaques characterized by an inflammatory infiltrate, mostly consisting activated lymphocytes,...
Clinical benefits of minimally invasive cardiac valve surgery (MIVS) have been reported. Improved postoperative mental status was never analyzed with dedicated psychological tests. In the present study we intend to investigate potential MIVS for patient well-being, special attention relevance perception chest surgical scar, self body image and cosmetic aspects.Between 2016 2017, 87 eligible patients, age 66.5 ± 14.5 years, operated on heart surgery, underwent either conventional full...
Objectives Aortic valve replacement (AVR) in patients with small aortic annulus (diameter ≤21 mm) is considered a challenging scenario because of technical aspects and the high risk patient-prosthesis mismatch (PPM). The choice appropriate prosthesis crucial, at moment, an ideal device has yet to be identified. We compare clinical hemodynamic results after AVR three bioprostheses different design characteristics. Methods retrospectively evaluated 76 consecutive from two cardiac surgery...
A 24-year-old woman was referred to our Cardiology Department because of cardiomegaly at a routine chest X-ray. She asymptomatic except for some fatigability. Physical examination unremarkable. Electrocardiogram showed only low QRS voltages. Echocardiography revealed large pericardial effusion with right atrial and ventricular collapse. Pericardiocentesis performed 1100 mL milky fluid were removed, suggesting chylopericardium. The …
A growing body of evidence suggests that inflammation plays a major role in the pathogenesis unstable angina; this is mainly derived from prognostic acute phase reaction proteins, such as C-reactive protein (CRP) and fibrinogen. Since production under control pro-inflammatory cytokines, it probable citokines, tumour-necrosis factor (TNF)-α, interleukin (IL)-1 IL-6 are involved same process. Indeed, elevated levels IL-1 have been found by our group others, patients with coronary syndromes....
An association between atrial myxoma and left ventricular failure is rarely described, not completely understood, may have multiple etiologies. We present a 49-year-old man with no history of cardiovascular disease who was admitted to our hospital pulmonary edema. He in fibrillation rapid response. Echocardiography showed 10.5-cm myxoma, which had been asymptomatic until the onset congestive heart presence severe systolic dysfunction. Left inflow obstruction associated giant mass could be...
Surgical ventricular reconstruction (SVR) is the therapy of choice for patients with left dilatation, apical and anterolateral transmural scar, low ejection fraction. STICH trial did not show that SVR led to improved survival but several observational studies did. However, because considerable operative risk, open heart surgery considered risky in debilitated clinical results are controversial. Alternative less invasive strategies aneurysm repair have been proposed. We present a case using...
A 51-year-old woman with exercise angina and a history of pulmonary artery hypertension related to previous thromboembolism, was referred our hospital. Computed tomography coronary angiography showed 95-mm aneurysm the main artery, which totally occluded left artery. After multidisciplinary evaluation, we recommended heart-lung transplantation, but patient refused any kind surgical procedure. Due chronic occlusion, stenting unfeasible. With no other options available, could only start...
Valvular heart disease (VHD) is frequently diagnosed in old patients with clinical evidence of failure. This elderly population typically presents a high prevalence frailty and comorbidities, which are associated increased operative risk for surgical percutaneous procedures. Recently, the Euro Heart Survey reported clear gap between treatment guidelines their application "real world". A more realistic approach to older VHD treatment, mostly if failure, advocated. multidisciplinary approach,...
Dynamic obstruction of right ventricle outflow tract (RVOTO) is a rare condition that may acutely cause severe heart failure. It has been reported in some hypertrophic cardiomyopathies, after lung transplantation, and cases hemodynamic instability cardiopulmonary bypass. We report the case 71-year-old man who developed hypotension during induction general anesthesia for surgical coronary revascularization. Hypotension did not respond to initial treatment with vasoconstrictors fluids. RVOTO...
OBJECTIVE We describe a minimally invasive echo-guided placement of the cardiac tube in ventriculoatrial shunt young pregnant woman, order to avoid any radiological procedure. METHODS used central venous catheter kit for percutaneous right internal jugular vein puncture located by 7.5 mHz microlinear probe. Through catheter, distal portion device was positioned into atrium using ultrasound control 2.5 3.5 probe four-chamber transthoracic view. RESULTS Sonographic guidance vertebral artery is...
Progressive right heart chambers dilatation is frequent in the adult congenital disease (ACHD) population. We evaluated immediate and mid-term response of to surgery performed adulthood for lesions associated with enlargement.Thirty-six patients enlargement submitted were studied. collected echocardiographic data ventricle (RV) mid-diameter, atrial volume indexed, RV systolic pressure, tricuspid annular plane excursion (TAPSE) prior (T0), at 2 5 days (T1), 3 6 months (T2) after surgery.At...