Gemma Pelargonio

ORCID: 0000-0003-3236-3458
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About
Contact & Profiles
Research Areas
  • Cardiac Arrhythmias and Treatments
  • Atrial Fibrillation Management and Outcomes
  • Cardiac pacing and defibrillation studies
  • Cardiac electrophysiology and arrhythmias
  • Cardiovascular Effects of Exercise
  • Cardiac Imaging and Diagnostics
  • Viral Infections and Immunology Research
  • Cardiac Structural Anomalies and Repair
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Syncope and Autonomic Disorders
  • Cardiomyopathy and Myosin Studies
  • Genetic Neurodegenerative Diseases
  • Infective Endocarditis Diagnosis and Management
  • Cardiovascular Function and Risk Factors
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • ECG Monitoring and Analysis
  • Sports injuries and prevention
  • Neurological disorders and treatments
  • Cardiac Arrest and Resuscitation
  • Mitochondrial Function and Pathology
  • Mechanical Circulatory Support Devices
  • Cardiovascular Issues in Pregnancy
  • Tissue Engineering and Regenerative Medicine
  • Cardiac Fibrosis and Remodeling
  • Central Venous Catheters and Hemodialysis

Università Cattolica del Sacro Cuore
2016-2025

Agostino Gemelli University Polyclinic
2005-2025

Istituti di Ricovero e Cura a Carattere Scientifico
2010-2025

University of the Sacred Heart
2006-2025

Ospedale generale di zona San Camillo Treviso
2023

Centro Cardiologico Monzino
2009-2023

Luigi Sacco Hospital
2020

John Wiley & Sons (United States)
2020

Hudson Institute
2020

Northwestern University
2020

Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure unknown.This was an open-label, randomized, parallel-group, multicenter study. Patients AF, dual-chamber implantable cardioverter defibrillator or cardiac resynchronization therapy defibrillator, New York Heart Association II III, and left ventricular ejection fraction <40% within past 6 months were randomly assigned (1:1 ratio) undergo CA AF...

10.1161/circulationaha.115.019406 article EN Circulation 2016-04-25

Pulmonary-vein isolation is increasingly being used to treat atrial fibrillation in patients with heart failure.In this prospective, multicenter clinical trial, we randomly assigned symptomatic, drug-resistant fibrillation, an ejection fraction of 40% or less, and New York Heart Association class II III failure undergo either pulmonary-vein atrioventricular-node ablation biventricular pacing. All completed the Minnesota Living Failure questionnaire (scores range from 0 105, a higher score...

10.1056/nejmoa0708234 article EN New England Journal of Medicine 2008-10-22

Background— Together with pulmonary veins, many extrapulmonary vein areas may be the source of initiation and maintenance atrial fibrillation. The left appendage (LAA) is an underestimated site Here, we report prevalence triggers from LAA best strategy for successful ablation. Methods Results— Nine hundred eighty-seven consecutive patients (29% paroxysmal, 71% nonparoxysmal) undergoing redo catheter ablation fibrillation were enrolled. Two sixty-six (27%) showed firing became study...

10.1161/circulationaha.109.928903 article EN Circulation 2010-07-07

Periprocedural thromboembolic and hemorrhagic events are worrisome complications of catheter ablation for atrial fibrillation (AF). The periprocedural anticoagulation management could play a role in the incidence these complications. Although procedures performed without warfarin discontinuation seem to be associated with lower risk, no randomized study exists.This was prospective, open-label, randomized, parallel-group, multicenter assessing continuous therapy preventing after...

10.1161/circulationaha.113.006426 article EN Circulation 2014-04-18

Background— Catheter ablation of atrial fibrillation is associated with the potential risk periprocedural stroke, which can range between 1% and 5%. We developed a prospective database to evaluate prevalence stroke over time assess whether anticoagulation strategy use open irrigation catheter have resulted in reduction this complication. Methods Results— collected data from 9 centers performing same procedure protocol. divided patients into 3 groups: an 8-mm off warfarin (group 1), irrigated...

10.1161/circulationaha.109.921320 article EN Circulation 2010-06-02

Background— In patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy, freedom from arrhythmias (VAs) after endocardial ablation is limited. We compared the long-term recurrent VAs by using endocardial-alone versus endo-epicardial substrate-based ablation. Methods and Results— Forty-nine dysplasia/cardiomyopathy undergoing of tachycardia (VT) were divided into 2 groups: (group 1, n=23) 2, n=26). All had an implantable cardioverter-defibrillator (ICD). Conventional 3D...

10.1161/circep.111.963066 article EN Circulation Arrhythmia and Electrophysiology 2011-06-11

Introduction: Atrial fibrillation (AF) and diabetes mellitus type 2 (DM2) often coexist; however, a small number of patients with DM2 undergoing catheter ablation (CA) AF have been included in previous studies. The aim this study was to evaluate safety efficacy therapy drug refractory AF. Methods Results: From January 2005 September 2006, 70 diagnosis paroxysmal (n = 29) or persistent 41) were randomized receive either pulmonary vein isolation new antiarrhythmic treatment (ADT) 1‐year...

10.1111/j.1540-8167.2008.01275.x article EN Journal of Cardiovascular Electrophysiology 2008-09-04

Whether different ablation strategies affect paroxysmal atrial fibrillation (AF) long-term freedom from AF/atrial tachyarrhythmia is unclear. We sought to compare the effect of 3 approaches on success in patients with AF.One hundred three consecutive AF scheduled for and presenting electrophysiology laboratory were selected this study. Patients randomized pulmonary vein antrum isolation (PVAI; n=35) versus biatrial complex fractionated electrograms (CFAEs; n=34) PVAI followed by CFAEs...

10.1161/circep.108.798447 article EN Circulation Arrhythmia and Electrophysiology 2009-02-19

Aim of this study was to compare a minimally fluoroscopic radiofrequency catheter ablation with conventional fluoroscopy-guided for supraventricular tachycardias (SVTs) in terms ionizing radiation exposure patient and operator estimate patients' lifetime attributable risks associated such exposure.We performed prospective, multicentre, randomized controlled trial six electrophysiology (EP) laboratories Italy. A total 262 patients undergoing EP studies SVT were perform approach (MFA)...

10.1093/europace/euv344 article EN cc-by-nc EP Europace 2015-11-10
Giuseppe Boriani Pietro Palmisano Federico Guerra Matteo Bertini Gabriele Zanotto and 95 more Carlo Lavalle Pasquale Notarstefano Michele Accogli Giovanni Bisignani Giovanni B. Forleo Maurizio Landolina Antonio D’Onofrio Renato Pietro Ricci Roberto De Ponti R. Luise Paul L.E. Grieco Antonio Pangallo Glauberto da Silva Quirino A Talarico Silvana De Bonis A. Carbone Alessio SİMONE Antonio D’Onofrio Felice Nappi Francesco Rotondi Giuseppe Stabile Carlo Uran Matteo Bertini Cristina Balla Giulio Boggian Valeria Carinci G. Barbato Alessandro Corzani Paolo Sabbatani M. Erminio Jacopo Francesco Imberti N. Malavasi Paolo Pastori Fabio Quartieri Nicola Bottoni Davide Saporito Santo Virzì Biagio Sassone Marco Zardini Angelo Placci Matteo Ziacchi Giulia Massaro Francesco Maria Adamo Alberto Scaccia A. Spampinato Francesco Biscione A. Castro Filippo Maria Cauti Pietro Rossi Claudio Cinti Miriam Gatto Amir Kol Maria Lucia Narducci Gemma Pelargonio N Patruno Carlo Pignalberi Renato Pietro Ricci Danilo Ricciardi Luca Santini Mauro Tancredi Natale Di Belardino F. Pentimalli Massimo Zoni-Berisso Giuseppina Belotti Enrico Chieffo Silvia Cilloni Lorenzo A. Doni Giovanni B. Forleo Andrea Gardini Daniele Malaspina Patrizio Mazzone P. Della Bella Roberto W. Dal Negro Giovanni Battista Perego Roberto Rordorf Laura Cipolletta Alessandra Russo Mario Luzi Claudia Amellone Elisa Ebrille Elisa Favro Maria Teresa Lucciola Chiara Devecchi Francesco Rametta Fausto Devecchi Mario Matta A. O. Sant’Andrea Matteo Santagostino Gabriele Dell’Era T. R. Candida V Bonfantino Domenico Gianfrancesco Alessandro Guido P L Pellegrino Ennio Pisanò

10.1007/s11739-020-02487-w article EN other-oa Internal and Emergency Medicine 2020-09-05

Intracoronary provocation testing with acetylcholine (ACh) is crucial for the diagnosis of functional coronary alterations in patients suspected myocardial ischaemia and non-obstructive arteries.Our intention was to assess safety predictive value major adverse cardiovascular cerebrovascular events (MACCE) presenting arteries (INOCA) or infarction (MINOCA).We prospectively enrolled consecutive INOCA MINOCA undergoing intracoronary ACh testing.A total 317 were enrolled: 174 (54.9%) 143 (45.1%)...

10.4244/eij-d-21-00971 article EN EuroIntervention 2022-10-01

Catheter ablation (CA) of atrial fibrillation is routinely used to obtain rhythm control. Evidence suggest that catheter should be done during uninterrupted oral anticoagulation.

10.23736/s2724-5683.24.06546-3 article EN Minerva Cardiology and Angiology 2024-05-30

We sought to test how catheter ablation using an open irrigation (OIC) compares with standard catheters for pulmonary vein antrum isolation. Open have the advantage of delivering greater power without increasing temperature tip, which enables deeper and wider lesions formation coagulum on catheters. Catheter was performed 8-mm (8MC) or OIC. Patients were randomized 3 groups: 8MC; OIC-1, OIC a higher peak (50 W); OIC-2, lower (35 W). A total 180 patients treatment strategies. Isolation antra...

10.1016/j.jacc.2006.12.041 article EN publisher-specific-oa Journal of the American College of Cardiology 2007-04-01
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