- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Viral Infections and Immunology Research
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Cardiomyopathy and Myosin Studies
- Genetic Neurodegenerative Diseases
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Takotsubo Cardiomyopathy and Associated Phenomena
- ECG Monitoring and Analysis
- Sports injuries and prevention
- Neurological disorders and treatments
- Cardiac Arrest and Resuscitation
- Mitochondrial Function and Pathology
- Mechanical Circulatory Support Devices
- Cardiovascular Issues in Pregnancy
- Tissue Engineering and Regenerative Medicine
- Cardiac Fibrosis and Remodeling
- Central Venous Catheters and Hemodialysis
Università Cattolica del Sacro Cuore
2016-2025
Agostino Gemelli University Polyclinic
2005-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2010-2025
University of the Sacred Heart
2006-2025
Ospedale generale di zona San Camillo Treviso
2023
Centro Cardiologico Monzino
2009-2023
Luigi Sacco Hospital
2020
John Wiley & Sons (United States)
2020
Hudson Institute
2020
Northwestern University
2020
Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure unknown.This was an open-label, randomized, parallel-group, multicenter study. Patients AF, dual-chamber implantable cardioverter defibrillator or cardiac resynchronization therapy defibrillator, New York Heart Association II III, and left ventricular ejection fraction <40% within past 6 months were randomly assigned (1:1 ratio) undergo CA AF...
Pulmonary-vein isolation is increasingly being used to treat atrial fibrillation in patients with heart failure.In this prospective, multicenter clinical trial, we randomly assigned symptomatic, drug-resistant fibrillation, an ejection fraction of 40% or less, and New York Heart Association class II III failure undergo either pulmonary-vein atrioventricular-node ablation biventricular pacing. All completed the Minnesota Living Failure questionnaire (scores range from 0 105, a higher score...
Background— Together with pulmonary veins, many extrapulmonary vein areas may be the source of initiation and maintenance atrial fibrillation. The left appendage (LAA) is an underestimated site Here, we report prevalence triggers from LAA best strategy for successful ablation. Methods Results— Nine hundred eighty-seven consecutive patients (29% paroxysmal, 71% nonparoxysmal) undergoing redo catheter ablation fibrillation were enrolled. Two sixty-six (27%) showed firing became study...
Periprocedural thromboembolic and hemorrhagic events are worrisome complications of catheter ablation for atrial fibrillation (AF). The periprocedural anticoagulation management could play a role in the incidence these complications. Although procedures performed without warfarin discontinuation seem to be associated with lower risk, no randomized study exists.This was prospective, open-label, randomized, parallel-group, multicenter assessing continuous therapy preventing after...
Background— Catheter ablation of atrial fibrillation is associated with the potential risk periprocedural stroke, which can range between 1% and 5%. We developed a prospective database to evaluate prevalence stroke over time assess whether anticoagulation strategy use open irrigation catheter have resulted in reduction this complication. Methods Results— collected data from 9 centers performing same procedure protocol. divided patients into 3 groups: an 8-mm off warfarin (group 1), irrigated...
Background— In patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy, freedom from arrhythmias (VAs) after endocardial ablation is limited. We compared the long-term recurrent VAs by using endocardial-alone versus endo-epicardial substrate-based ablation. Methods and Results— Forty-nine dysplasia/cardiomyopathy undergoing of tachycardia (VT) were divided into 2 groups: (group 1, n=23) 2, n=26). All had an implantable cardioverter-defibrillator (ICD). Conventional 3D...
Introduction: Atrial fibrillation (AF) and diabetes mellitus type 2 (DM2) often coexist; however, a small number of patients with DM2 undergoing catheter ablation (CA) AF have been included in previous studies. The aim this study was to evaluate safety efficacy therapy drug refractory AF. Methods Results: From January 2005 September 2006, 70 diagnosis paroxysmal (n = 29) or persistent 41) were randomized receive either pulmonary vein isolation new antiarrhythmic treatment (ADT) 1‐year...
Whether different ablation strategies affect paroxysmal atrial fibrillation (AF) long-term freedom from AF/atrial tachyarrhythmia is unclear. We sought to compare the effect of 3 approaches on success in patients with AF.One hundred three consecutive AF scheduled for and presenting electrophysiology laboratory were selected this study. Patients randomized pulmonary vein antrum isolation (PVAI; n=35) versus biatrial complex fractionated electrograms (CFAEs; n=34) PVAI followed by CFAEs...
Aim of this study was to compare a minimally fluoroscopic radiofrequency catheter ablation with conventional fluoroscopy-guided for supraventricular tachycardias (SVTs) in terms ionizing radiation exposure patient and operator estimate patients' lifetime attributable risks associated such exposure.We performed prospective, multicentre, randomized controlled trial six electrophysiology (EP) laboratories Italy. A total 262 patients undergoing EP studies SVT were perform approach (MFA)...
Intracoronary provocation testing with acetylcholine (ACh) is crucial for the diagnosis of functional coronary alterations in patients suspected myocardial ischaemia and non-obstructive arteries.Our intention was to assess safety predictive value major adverse cardiovascular cerebrovascular events (MACCE) presenting arteries (INOCA) or infarction (MINOCA).We prospectively enrolled consecutive INOCA MINOCA undergoing intracoronary ACh testing.A total 317 were enrolled: 174 (54.9%) 143 (45.1%)...
Catheter ablation (CA) of atrial fibrillation is routinely used to obtain rhythm control. Evidence suggest that catheter should be done during uninterrupted oral anticoagulation.
We sought to test how catheter ablation using an open irrigation (OIC) compares with standard catheters for pulmonary vein antrum isolation. Open have the advantage of delivering greater power without increasing temperature tip, which enables deeper and wider lesions formation coagulum on catheters. Catheter was performed 8-mm (8MC) or OIC. Patients were randomized 3 groups: 8MC; OIC-1, OIC a higher peak (50 W); OIC-2, lower (35 W). A total 180 patients treatment strategies. Isolation antra...