- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cardiac tumors and thrombi
- Antiplatelet Therapy and Cardiovascular Diseases
- Viral Infections and Immunology Research
- Cardiovascular Effects of Exercise
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiomyopathy and Myosin Studies
- Vascular anomalies and interventions
- Venous Thromboembolism Diagnosis and Management
- Neurological disorders and treatments
- ECG Monitoring and Analysis
- Acute Myocardial Infarction Research
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- Orthopaedic implants and arthroplasty
- Coronary Artery Anomalies
- Antimicrobial Resistance in Staphylococcus
- Coronary Interventions and Diagnostics
- Parkinson's Disease Mechanisms and Treatments
Vita-Salute San Raffaele University
2013-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2019-2025
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2023-2025
Metropolitana Milanese (Italy)
2024-2025
Società Italiana di Reumatologia
2025
IRCCS Ospedale San Raffaele
2014-2024
Azienda Ospedaliero Universitaria di Sassari
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2024
San Raffaele University of Rome
2011-2024
Ospedale Maggiore
2024
The pulmonary veins (PVs) and surrounding ostial areas frequently house focal triggers or reentrant circuits critical to the genesis of atrial fibrillation (AF). We developed an anatomic approach aimed at isolating each PV from left atrium (LA) by circumferential radiofrequency (RF) lesions around their ostia.We selected 26 patients with resistant AF, either paroxysmal (n=14) permanent (n=12). A nonfluoroscopic mapping system was used generate 3D electroanatomic LA maps deliver RF energy....
Circumferential radiofrequency ablation around pulmonary vein (PV) ostia has recently been described as a new anatomic approach for atrial fibrillation (AF).We treated 251 consecutive patients with paroxysmal (n=179) or permanent (n=72) AF. Circular PV lesions were deployed transseptally during sinus rhythm (n=124) AF (n=127) using 3D electroanatomic guidance. Procedures lasted 148+/-26 minutes. Among 980 surrounding individual PVs (n=956) 2 ipsilateral veins close openings common ostium...
Background: Left atrial appendage occlusion with WATCHMAN has emerged as viable alternative to vitamin K antagonists in randomized controlled trials. Evaluating real-life clinical outcomes fibrillation patients receiving the left closure technology was designed collect prospective multicenter of thromboembolic events, bleeding, and mortality for implanted a routine daily practice. Methods: One thousand twenty implant procedure were prospectively followed 47 centers. indication based on...
Ventricular fibrillation can be the presenting arrhythmia in children with asymptomatic Wolff–Parkinson–White syndrome. Deaths due to this are potentially preventable.
Background— The aim was to relate distinct scar distributions found in nonischemic cardiomyopathy with ventricular tachycardia (VT) morphology, late potential distribution, ablation strategy, and outcome. Methods Results— Eighty-seven patients underwent catheter for drug-refractory VT. Based on endocardial unipolar voltage, 44 were classified as predominantly anteroseptal 43 inferolateral. Anteroseptal more frequently fulfilled diagnostic criteria dilated (64% versus 36%), associated...
Successful late potential (LP) abolition and postprocedural ventricular tachycardia (VT) noninducibility constitute significant end points after catheter ablation for VT. We investigated the prognostic impact of a combined procedural point VT LP in large series post-myocardial infarction patients with VT.A total 160 (154 men, 94% implantable cardioverter defibrillators) consecutive undergoing first-time procedures from 2010 to 2012 were included. Of 159 surviving procedure, 137 (86%) either...
Several large studies have documented the outcome of transvenous lead extraction (TLE), focusing on laser and mechanical methods. To date there has been no series addressing results obtained with rotational tools. This retrospective multicentre study was designed to investigate outcomes techniques.Data were collected a total 2205 patients (age 66.0 ± 15.7 years) 3849 leads targeted for in six European centres. The commonest indication infection (46%). included 2879 pacemaker (74.8%), 949...
Myocardial infarction with nonobstructive coronary arteries (MINOCA) is an increasingly recognized condition, a higher incidence in women, characterized by myocardial injury without significant artery obstruction. Sex-specific differences play critical role its pathophysiology, clinical presentation, and response to treatment. While the underlying mechanisms of MINOCA are diverse—including microvascular dysfunction, spasm, plaque rupture, dissection, thromboembolism—women more frequently...