Ottavio Alfieri
A5079620351- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Coronary Interventions and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Pulmonary Hypertension Research and Treatments
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiomyopathy and Myosin Studies
- Cardiac Arrest and Resuscitation
- Cardiac tumors and thrombi
- Cardiac Ischemia and Reperfusion
- Pericarditis and Cardiac Tamponade
- Antiplatelet Therapy and Cardiovascular Diseases
- Hemodynamic Monitoring and Therapy
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2015-2025
Vita-Salute San Raffaele University
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Mylan (South Africa)
2025
San Raffaele University of Rome
2015-2024
Fondazione Italiana di Ricerca per la Sclerosi Laterale Amiotrofica
2020-2024
IRCCS Ospedale San Raffaele
2015-2024
Charité - Universitätsmedizin Berlin
2024
Institute of Cardiology
2024
Heart Foundation
2021-2024
The ESC Guidelines represent the views of and were arrived at after careful consideration available evidence time they written.Health professionals are encouraged to take them fully into account when exercising their clinical judgement.The guidelines do not, however, override individual responsibility health make appropriate decisions in circumstances patients, consultation with that patient, where necessary patient's guardian or carer.It is also professional's verify rules regulations...
Mathematical support for phonocardiographic signal processing has been developed based on a mathematical model in the form of periodically correlated stochastic process and component method.On basis support, algorithmic software was Matlab environment automated systems computer diagnostics functional state valves human heart when mitral insufficiency is detected.
2012 focused update of the ESC Guidelines for management atrial fibrillation : an 2010 fibrillation: developed with special contribution European Heart Rhythm Association
The ESC/EACTS Guidelines represent the views of ESC and EACTS were arrived at after careful consideration available evidence time they written.Health professionals are encouraged to take them fully into account when exercising their clinical judgement.The guidelines do not, however, override individual responsibility health make appropriate decisions in circumstances patients, consultation with that patient and, where necessary, patient's guardian or carer.It is also professional's verify...
Guidelines and Expert Consensus Documents summarize evaluate all available evidence with the aim of assisting physicians in selecting best management strategy for an individual patient suffering from a given condition, taking into account impact on outcome risk–benefit ratio diagnostic or therapeutic means. are no substitutes textbooks their legal implications have been discussed previously. recommendations should help to make decisions daily practice. However, ultimate judgement regarding...
The ESC Guidelines represent the views of and were arrived at after careful consideration available evidence
Guidelines summarize and evaluate all currently available evidence on a particular issue with the aim of assisting physicians in selecting best management strategy for an individual patient suffering from given condition, taking into account impact outcome, as well risk–benefit ratio diagnostic or therapeutic means. are no substitutes textbooks. The legal implications medical guidelines have been discussed previously. A large number issued recent years by European Society Cardiology (ESC)...
There are no data to evaluate the relationship between autonomic nerve function modification and recurrent atrial fibrillation (AF) after circumferential pulmonary vein ablation (CPVA). This study assesses incremental benefit of vagal denervation by radiofrequency in preventing AF a large series patients undergoing CPVA for paroxysmal AF.Data were collected on 297 AF. Abolition all evoked reflexes around ostia was defined as complete (CVD) obtained 34.3% patients. Follow-up ended at 12...
Phase I clinical studies have demonstrated the feasibility of implanting autologous skeletal myoblasts in postinfarction scars. However, they failed to determine whether this procedure was functionally effective and arrhythmogenic.This multicenter, randomized, placebo-controlled, double-blind study included patients with left ventricular (LV) dysfunction (ejection fraction < or = 35%), myocardial infarction, indication for coronary surgery. Each patient received either cells grown from a...
Radiofrequency ablation for atrial fibrillation is becoming widely practiced.Two patients undergoing circumferential pulmonary vein in different centers developed symptoms compatible with endocarditis 3 to 5 days after the procedure. Their clinical condition deteriorated rapidly, and both suffered multiple gaseous and/or septic embolic events causing cerebral myocardial damage. One patient survived emergency cardiac esophageal surgery; other died of extensive systemic embolization. An...
Circumferential radiofrequency ablation around pulmonary vein (PV) ostia has recently been described as a new anatomic approach for atrial fibrillation (AF).We treated 251 consecutive patients with paroxysmal (n=179) or permanent (n=72) AF. Circular PV lesions were deployed transseptally during sinus rhythm (n=124) AF (n=127) using 3D electroanatomic guidance. Procedures lasted 148+/-26 minutes. Among 980 surrounding individual PVs (n=956) 2 ipsilateral veins close openings common ostium...
AimsTo critically review the available transcatheter aortic valve implantation techniques and their results, as well propose recommendations for use development.
The ESC/EACTS Guidelines represent the views of ESC and EACTS were produced after careful consideration scientific medical knowledge evidence available at time their publication.The are not responsible in event any contradiction, discrepancy and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals encouraged take fully into account when exercising...
Repair of mitral regurgitation (MR) is more demanding in case prolapse the anterior leaflet, posterior leaflet with calcified annulus, or both leaflets. We evaluated a repair which consists anchoring free edge prolapsing to corresponding facing leaflet: 'edge-to-edge' (E-to-E) technique. The correction results double orifice valve when middle portion and smaller close commissure.Out 432 patients MR submitted between January 1991 September 1997, 121 (mean age 56 +/- 15.8 years) underwent...
Background: Current surgical and medical treatment options for severe tricuspid regurgitation (TR) are limited, additional interventional approaches required. In the present observational study, safety feasibility of transcatheter repair chronic TR with MitraClip system were evaluated. addition, effects on clinical symptoms assessed. Methods: Patients heart failure optimal treated system. Safety, defined as periprocedural adverse events such death, myocardial infarction, stroke, or cardiac...
Background— Improvements in results with percutaneous coronary intervention (PCI) drug-eluting stents (DES) may extend their use patients left main artery (LMCA) stenosis. Methods and Results— Two hundred forty-nine LMCA stenosis were treated PCI DES implantation (n=107) or bypass grafting (CABG) (n=142), a single center, between March 2002 July 2004. A propensity analysis was performed to adjust for baseline differences the two cohorts. At 1 year, there no statistical difference occurrence...
To critically review the available transcatheter aortic valve implantation techniques and their results, as well propose recommendations for use development.A committee of experts including European Association Cardio-Thoracic Surgery Society Cardiology representatives met to reach a consensus based on analysis data obtained with own experience. The evidence suggests that this technique is feasible provides haemodynamic clinical improvement up 2 years in patients severe symptomatic stenosis...
Guidelines on the management of valvular heart disease (version 2012). The Joint Task Force Management Valvular Heart Disease European Society Cardiology (ESC) and Association for Cardio-Thoracic Surgery (EACTS)
Valve thrombosis has yet to be fully evaluated after transcatheter aortic valve implantation. This study aimed report the prevalence, timing, and treatment of heart (THV) thrombosis.THV was defined as follows (1) THV dysfunction secondary diagnosed based on response anticoagulation therapy, imaging modality or histopathology findings, (2) mobile mass detected suspicious thrombus, irrespective in absence infection. Between January 2008 September 2013, 26 (0.61%) thromboses were reported out...