A5028132682- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Lung Cancer Treatments and Mutations
- Radiopharmaceutical Chemistry and Applications
- Glycosylation and Glycoproteins Research
- Meningioma and schwannoma management
- Management of metastatic bone disease
- Radiomics and Machine Learning in Medical Imaging
- Advanced Radiotherapy Techniques
- Ferroptosis and cancer prognosis
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Galectins and Cancer Biology
- Cancer Genomics and Diagnostics
- Chemokine receptors and signaling
- Vascular Malformations Diagnosis and Treatment
- Immune Cell Function and Interaction
- Cancer, Lipids, and Metabolism
- Helicobacter pylori-related gastroenterology studies
- Chronic Lymphocytic Leukemia Research
- CNS Lymphoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Head and Neck Surgical Oncology
Institut Català d'Oncologia
2012-2024
Duran i Reynals Hospital
2024
Hospital Universitari Germans Trias i Pujol
2019
European Bioinformatics Institute
2016
Wellcome Trust
2016
Hospital Xeral Calde
2013
Institut d'Investigació Biomédica de Bellvitge
2012
Inhibitors of the mechanistic target rapamycin (mTOR) are currently used to treat advanced metastatic breast cancer. However, whether an aggressive phenotype is sustained through adaptation or resistance mTOR inhibition remains unknown. Here, complementary studies in human tumors, cancer models and cell lines reveal transcriptional reprogramming that supports metastasis response inhibition. This feature driven by EVI1 SOX9. functionally cooperates with positively regulates SOX9, promotes...
In order to assess whether inherited genetic variability in the mucin genes associates with evolution of gastric cancer precursor lesions (GCPLs), we genotyped 22 tagSNPs MUC1 , MUC6 and MUC2 387 patients GCPLs that had been followed up for 12.8 years. According diagnosis at recruitment end follow-up, did not change 43.1% patients, regressed 28.7% progressed 28.2%. Three SNPs 3′-moiety were significantly associated a decreased risk progression lesions, whereas another four SNPs, located...
Background: Surgery and stereotactic body radiotherapy (SBRT) are two of the options available as local treatments for pulmonary oligometastases from colorectal cancer (CRC). We hypothesized that SBRT would have, at least, a similar control rate to surgery. Methods: identified an initial cohort 100 patients with CRC who received or surgery lung metastases. This was then narrowed down 75 patients: those underwent (n = 50) 25) their first thoracic treatment between 1 January 2004 29 December...
Abstract BACKGROUND Trigeminal schwannomas (TS) represent 1-8% of all intracranial and 0.1-0.5% tumors Treatment strategies are mainly based on limited published data case reports. The most common treatment is surgical resection. However, it can rarely be completed. Fractionated stereotactic radiotherapy (FSRT) has the potential to a valuable safe alternative control growing or symptomatic TS. aim this review analyze clinical RESULTS , toxicity tumor rates obtained with technique when...
Intracranial squamous cell carcinoma (SCC) is a rare condition and relatively few cases have been described in the literature.Despite poor prognosis, no standardized treatment protocols developed.In present article, we report case of primary intracranial SCC with review literature.A 42-year-old woman presented right cerebellopontine angle.The patient underwent gross total resection tumour followed by adjuvant radiotherapy (50 Gy 25 fractions).The died 26 months after initial due to...
Introduction: Around 30% of DLBCL patients present a refractory/relapsing disease following R-CHOP. Rituximab-containing salvage chemotherapy followed by autologous stem cell transplant (ASCT) in chemosensitive remains the standard care. We aimed to study clinical features and outcome diagnosed DLBCL, homogeneously treated first line with R-CHOP/R-CHOP–like who have primary refractory (PRD). Methods: Three hundred sixty-seven were between January 2004 August 2016; 317/367 (86.3%)...