Nicholas Kirui

ORCID: 0000-0003-1382-7165
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About
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Research Areas
  • Tuberculosis Research and Epidemiology
  • Chronic Disease Management Strategies
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • HIV-related health complications and treatments
  • Cardiovascular Function and Risk Factors
  • HIV/AIDS Research and Interventions
  • Diabetes Management and Education
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Respiratory viral infections research
  • Metabolism, Diabetes, and Cancer
  • Global Cancer Incidence and Screening
  • Diverse Scientific Research Studies
  • Online and Blended Learning
  • Platelet Disorders and Treatments
  • Cervical Cancer and HPV Research
  • Transport Systems and Technology
  • Pharmacogenetics and Drug Metabolism
  • Homelessness and Social Issues
  • Transportation and Mobility Innovations
  • Complement system in diseases
  • Smart Grid Energy Management
  • Vaccine Coverage and Hesitancy
  • Telemedicine and Telehealth Implementation
  • Renal Diseases and Glomerulopathies
  • Healthcare Systems and Reforms

Moi University
2013-2024

Dedan Kimathi University of Technology
2023

Ministry of Health
2021

AMPATH
2012-2021

Johns Hopkins Hospital
2019

Duke University
2019

Aga Khan University Nairobi
2016

Aga Khan University Hospital Nairobi
2016

United States Agency for International Development
2012

The words 'defaulter', 'suspect' and 'control' have been part of the language tuberculosis (TB) services for many decades, they continue to be used in international guidelines published literature. From a patient perspective, it is our opinion that these terms are at best inappropriate, coercive disempowering, worst could perceived as judgmental criminalising, tending place blame disease or responsibility adverse treatment outcomes on one side-that patients. In this article, which brings...

10.5588/ijtld.11.0635 article EN The International Journal of Tuberculosis and Lung Disease 2012-05-14

Traditional cardiovascular disease (CVD) risk factors contribute to increase of CVD in people living with HIV (PLWH). Of all world regions, sub-Saharan Africa has the highest prevalence yet little is known about PLWH's knowledge and self- perceived for coronary heart (CHD). In this study, we assessed knowledge, perception attitude towards diseases their prevention.We conducted a cross-sectional study largest care program western Kenya. Trained research assistants used validated...

10.1186/s12879-015-1157-8 article EN cc-by BMC Infectious Diseases 2015-10-14

T he global burden of diabetes mellitus (DM) is in- creasing exponentially, with the highest increases occurring in low-and middle-income countries (LMICs). 1,2In 2015, 415 million (8.8%) world's population had DM, two thirds those sub-Saharan Africa region remaining undiagnosed. 3his pandemic resulted 5 DM-associated deaths globally.The prevalence DM expected to reach 10.4% by 2040.Tuberculosis (TB) remains a major cause morbidity and mortality worldwide, an estimated 10.4 people developing...

10.5588/pha.16.0114 article EN cc-by Public Health Action 2017-06-21

Metabolic syndrome (MetS), a cluster of cardiovascular disease risk factors, is increasingly common in people living with HIV; however, data on prevalence and the role antiretroviral therapy (ART) as factor for MetS sub-Saharan Africa are lacking. We conducted cross-sectional study to assess factors among ART-naive ART-experienced HIV-infected adults without preexisting cardiometabolic disorders Western Kenya using validated questionnaires laboratory tests after overnight fasting. used...

10.1089/apc.2018.0052 article EN AIDS Patient Care and STDs 2018-05-31

Abstract Aims To determine the characteristics of patients with diabetes who reported food insecurity at three clinics in western Kenya. Methods This study includes routinely collected demographic data first presentation Kenya from 1 January 2006 to 24 September 2011. A validated questionnaire was used assess descriptive and comparative statistics being analyse food‐secure food‐insecure populations. Results The number presenting these were those 1179 (68.0%) 554 (32.0%), respectively....

10.1111/dme.12174 article EN Diabetic Medicine 2013-03-18

Sub-Saharan Africa continues to face the highest rate of mortality from diabetes in world due limited access quality care. We assessed care a rural clinic western Kenya. To provide comprehensive assessment, set clinical outcomes, process, and structure metrics were evaluated assess provided outpatient at Webuye District Hospital. The primary outcome measures change HbA1c point blood glucose. In assessing process metrics, measure was percentage patients who lost follow up. by evaluating...

10.1186/s12902-018-0324-5 article EN cc-by BMC Endocrine Disorders 2018-12-01

There has been considerable concern regarding the rapidly growing prevalence of diabetes, particularly in resource-rich settings as a result shift toward more sedentary lifestyles that occurs with calorie-rich diets (1). Although much global attention to diabetes focused on and emerging markets, epidemic also expanding resource-constrained such sub-Saharan Africa (2). Estimates from International Diabetes Federation suggest is expected increase by 98% 2030, contrast an 54% rest world (3)....

10.2337/diaclin.33.3.136 article EN cc-by-nc-nd Clinical Diabetes 2015-07-01

Objectives Diastolic dysfunction (DD) has been reported to be highly prevalent in people living with HIV (PLWH) on antiretroviral therapy (ART) leading the hypothesis that it may an early marker of myocardial disease. Our objective was evaluate prevalence DD human immunodeficiency virus without known history diabetes or hypertension Western Kenya. Methods In this cross-sectional study western Kenya, 110 PLWH ART and were matched for age ±5 years sex HIV-uninfected controls. Study...

10.1136/openhrt-2021-001814 article EN cc-by-nc Open Heart 2022-01-01

Rifampicin's ability to induce hepatic enzymes is responsible for causing a clinically significant drug interaction with warfarin. Little data exists guide clinicians on managing this interaction, especially in Sub-Saharan Africa where many patients are exposed combination due higher burden of tuberculosis.The objective the case series provide insight practicing unique dynamics resource-constrained settings. The will details commonly encountered scenarios and dosage adjustments required...

10.1007/s40268-013-0023-7 article EN cc-by-nc Drugs in R&D 2013-08-27

Diabetes clinics in three hospitals Western Kenya: Moi Teaching and Referral Hospital two associated district hospitals. To determine the proportion of diabetes patients with a history tuberculosis ( TB), human immunodeficiency virus (HIV ) infection tobacco smoking. A descriptive study using routinely collected data from patient records clinics. Of 1376 analyzed, 750 (55%) were female. The mean age was 53.5 years (95%CI 52.2-54.8), an average duration 8.1 7.6-8.7). all patients, 5.6%...

10.5588/pha.12.0031 article EN cc-by Public Health Action 2012-11-13

To evaluate the impact of clinician-targeted mHealth-generated care suggestions on compliance with hypertension guidelines in a resource-limited setting. This study was conducted 10 rural health clinics Western Kenya that offered through nurses and clinical officers. Sites were grouped into intervention control groups. Intervention group clinicians had patient-specific triggered displayed mobile application, mUzima, for their action. Care also mHealth application arm but not displayed....

10.3233/shti230966 article EN cc-by-nc Studies in health technology and informatics 2024-01-25

This study addresses the challenges posed by conventional energy meters, which rely on manual readings, leading to human errors and inefficiencies. In response this, a battery-powered smart meter was developed utilizing an STM32 microcontroller, ADE7758 STPM32 metering integrated circuits (ICs), SIM ESP32 communication modules, along with MYSQL database. Real-time data from both single three-phase appliances were collected, their consumption, errors, Mean Absolute Error (MAE), Root Squared...

10.25077/ajeeet.v3i2.63 article EN cc-by-nc-sa Andalas Journal of Electrical and Electronic Engineering Technology 2023-12-30

Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder with no prevalence or incidence studies in sub-Saharan Africa. Acquired TTP has several causes, all of which lead to decreased activity von Willebrand factor cleaving protease (ADAMTS13) due autoantibodies that are directed towards ADAMTS13. We report case 46-year-old man who presented most the classic clinical manifestations TTP.

10.7196/samj.2016.v106i7.9856 article EN cc-by-nc South African Medical Journal 2016-06-17

<ns4:p><ns4:bold>Background</ns4:bold>:</ns4:p><ns4:p> It is unclear if adjunctive steroid therapy reduces mortality in community-acquired pneumonia, as very few studies have had a primary outcome. This question has become even more relevant following demonstration of benefit dexamethasone when used patients with COVID-19 who severe disease. led to increased prescription steroids adults community acquired pneumonia low-resource settings their diagnosis uncertain due low testing...

10.12688/wellcomeopenres.18401.1 preprint EN cc-by Wellcome Open Research 2022-10-27

Abstract Cancer is a major cause of morbidity and mortality globally. This study aimed to determine the preparedness public health care facilities in provision breast cervical cancer services by assessing healthcare provider’s knowledge on risk factors, screening, symptoms, diagnosis treatment diseases as well availability medical equipment required their management Western Kenya. was achieved using cross-sectional service assessment (SPA) baseline survey technique Busia Trans-Nzoia counties...

10.1101/2021.05.24.21257702 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-05-26
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