A5101721667- Ovarian function and disorders
- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Uterine Myomas and Treatments
- Reproductive Biology and Fertility
- Circular RNAs in diseases
- Hair Growth and Disorders
- MicroRNA in disease regulation
- Hemoglobinopathies and Related Disorders
- Erythrocyte Function and Pathophysiology
- Blood properties and coagulation
- Genetic factors in colorectal cancer
- Garlic and Onion Studies
- Sexual Differentiation and Disorders
- Diabetes and associated disorders
- PARP inhibition in cancer therapy
- Cancer-related molecular mechanisms research
- Gynecological conditions and treatments
- Liver Diseases and Immunity
- Hormonal and reproductive studies
- Tannin, Tannase and Anticancer Activities
- Retinal and Optic Conditions
- Plant tissue culture and regeneration
- Adipose Tissue and Metabolism
- Growth Hormone and Insulin-like Growth Factors
Jiangxi Provincial Children's Hospital
2019-2024
Huazhong University of Science and Technology
2012-2023
Tongji Hospital
2012-2023
UNSW Sydney
2022
Wuhan University
2015
Zhongnan Hospital of Wuhan University
2015
Recently, the gut microbiota has been found to be associated with multiple organs and systems in human body, playing a key role occurrence development of various diseases, such as gut–brain axis gut–liver axis. However, its interaction miscarriages remains poorly understood. This article reviews characteristics metabolites patients recurrent spontaneous abortion (RSA), mechanism inducing RSA, potential therapeutic strategies. Therefore, it provides new perspective on pathogenesis treatment...
Abstract Evidence accumulated in recent years has revealed that neutrophils are involved the initial establishment of endometriosis, which is well-known as a chronic inflammatory disease. So far, why and how promote formation early endometriosis still unclear. In this study, using mouse model we demonstrated mice (EMs mice) had significantly increased number peritoneal fluids lesions, levels granulocyte colony-stimulating factor (G-CSF) IL-6 serum compared to control group. uterine fragments...
Polycystic ovary syndrome (PCOS) is a common, multifactorial disorder characterized by endocrine, reproductive, and metabolic dysfunction. As the etiology of PCOS unknown, there no cure symptom-oriented treatments are suboptimal. Hyperandrogenism key diagnostic trait, evidence suggests that androgen receptor (AR)-mediated actions critical to pathogenesis. However, AR target sites involved remain be fully defined. Adipocyte muscle dysfunction proposed as important in manifestation traits. We...
To investigate the clinical and genetic characteristics of hereditary spherocythemia (HS) in Chinese children, to analyze potential genotypic/phenotypic associations.The data gene test results children with HS were collected. All patients diagnosed by results, laboratory obtained before splenectomy. The red blood cell (RBC), hemoglobin (HB), mean volume (MCV), (MCH), concentration (MCHC), hematocrit (HCT) statistically analyzed according different mutation genes. Statistical methods for...
Endometriosis is a gynecological disease with abnormal expression of interleukin (IL)-37 which can suppress inflammation and the immune system. Here we investigated role IL-37b splice variant in endometriosis vivo vitro. In murine model endometriosis, administration significantly inhibited development lesions judged by number (P = 0.0213), size 0.0130) weight 0.0152) lesions. had no effect on early stage lesion formation, however growth decreased 0.0158), 0.0158) 0.0258) compared PBS...
The aim of this study was to evaluate the potential biological activity N-(6-oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride (PJ34) on genotoxicity induced by melphalan in human multiple myeloma cells.The inhibitory effects drugs growth RPMI8226 cells were determined Cell Counting Kit-8 (CCK-8) assay. expression Fanconi anemia/breast cancer (FA/BRCA) pathway related genes western blot analysis. cycle phase and apoptosis analyzed flow cytometry. Coadministration...
To investigate the effects of ranibizumab combined with laser photocoagulation on macular volume and best corrected visual acuity (BCVA) in patients edema secondary to ischemic retinal vein occlusion.The clinical data 90 (90 eyes) occlusion treated our hospital from June 2018 December 2021 were retrospectively analyzed. Patients divided into Groups-A, B, C according type treatment they received. The Group-A was photocoagulation, Group-B intravitreally injected ranibizumab, Group-C underwent...
This study aimed to investigate the clinical features, pathogenic gene variants, and potential genotype-phenotype correlations in Chinese patients with hereditary spherocytosis (HS).
Background: Polycystic ovary syndrome (PCOS) is a common disorder characterised by endocrine, reproductive and metabolic dysfunction. Hyperandrogenism key diagnostic trait evidence supports role for androgen receptor (AR) mediated actions in PCOS pathogenesis. Aberrant AR signalling adipose tissue muscle have been proposed as being involved pathogenesis, but their importance the precise mechanisms remain undefined. Aim: To investigate of white (WAT), brown (BAT) skeletal development PCOS....