A5039564333- Head and Neck Cancer Studies
- Oral and Maxillofacial Pathology
- Oral Health Pathology and Treatment
- Cancer-related Molecular Pathways
- Cancer-related gene regulation
- Bone and Dental Protein Studies
- RNA modifications and cancer
- dental development and anomalies
- MicroRNA in disease regulation
- Glutathione Transferases and Polymorphisms
- Acute Lymphoblastic Leukemia research
- Cancer-related molecular mechanisms research
- Skin and Cellular Biology Research
- Infectious Diseases and Mycology
- Cancer, Hypoxia, and Metabolism
- Epigenetics and DNA Methylation
- Cervical Cancer and HPV Research
- Cancer and Skin Lesions
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Ubiquitin and proteasome pathways
- Fluoride Effects and Removal
- Circular RNAs in diseases
- Childhood Cancer Survivors' Quality of Life
- Cancer Cells and Metastasis
- Oral microbiology and periodontitis research
Mahidol University
2006-2024
Bangkok University
2023
Background: Expression of p16 has been proposed as a marker for malignant transformation. This study aimed to evaluate expression in oral squamous cell carcinoma (OSCC) and premalignant lesions including leukoplakia (OL) with without dysplasia. Methods: was investigated 56 samples OSCC, OL dysplasia, normal mucosa. identified by immunohistochemistry, using the CINtecTM p16INK4a Histology Kit. Both nuclear and/or cytoplasmic staining keratinocytes were considered be positive percentage cells...
Type VII collagen (Col7) is a major component of anchoring fibrils. Col7 plays role in tumor development and aggressiveness cutaneous squamous cell carcinoma recessive dystrophic epidermolysis bullosa. However, the oral (OSCC) leukoplakia (OL) remains largely unknown. To elucidate its diagnostic potential during carcinogenesis. expression was immunohistochemically studied 254 samples, including normal mucosa (NM), OL without dysplasia, with OSCC. The correlation between clinicopathologic...
Little is known about the role of cytokeratin 17 (CK17) during oral carcinogenesis. CK17 expression in leukoplakia (OL), most encountered potentially malignant disorders and squamous cell carcinoma (OSCC), remains very limited. To determine carcinogenesis its potential diagnostic marker premalignant lesions, this study evaluated OL without dysplasia, with OSCC. these tissues was compared those normal mucosa (NOM). Additionally, relationship between clinicopathologic factors OSCC...
Objectives: This study assessed associations of the miR196a2 (rs11614913) T>C polymorphism withsusceptibility to childhood acute lymphoblastic leukemia (ALL) and clinical outcomes. Materials Methods: Blood DNA samples from 104 ALL patients 180 healthy children were studied for miR-196a2 using a polymerase chain reaction-restriction fragment-length (PCR-RFLP) approach. Results: The frequency T allele in controls was 0.51 compared with 0.33 cases. In this study, CC, TC heterozygote CC/TC...
Ameloblastoma (AM) is a prominent benign odontogenic tumor characterized by aggressiveness, likely originating from tooth‑generating tissue or the dental follicle (DF). However, proteomic distinctions between AM and DF remain unclear. In present study, aim was to identify distinction in terms of their proteome determine associated hub genes. Shotgun proteomics used compare proteomes seven fresh‑frozen tissues five tissues. Differentially expressed proteins (DEPs) were quantified subsequently...
MiR27a plays an important role in carcinogenesis, cell proliferation, apoptosis, invasion, migration and angiogenesis. Several studies have identified of pre-miR27a (rs895819) A>G polymorphism several types cancer. This research aims to investigate the association breast cancer susceptibility, clinicopathological data survival. Blood DNA samples 143 Thai patients 100 healthy women were studied for using polymerase chain reaction-restriction fragment-length (PCR-RFLP).The results revealed...
DNA methylation regulates the expression of various genes involved in tumorigenesis. Ameloblastoma is a benign odontogenic jaw tumor. It locally aggressive with high level recurrence. A delay treatment can lead to severe facial disfigurement. To best our knowledge, this first integrated analysis and gene ameloblastoma aim identify that may be regulated by methylation.We used an Infinium MethylationEPIC array measure genome-wide Illumina HiSeq platform obtain data tissues from five patients...
Abstract Background Secreted protein acidic and rich in cysteine (SPARC) has been shown to modulate aggressive behavior several benign malignant tumors. Little is known about SPARC expression odontogenic keratocyst (OKC), an cyst with nature. To the best of our knowledge, only one study investigated this OKCs. This aimed characterize Additionally, determine whether associated OKCs, OKCs was compared radicular cysts (RCs), dentigerous (DCs) calcifying (COCs). These showed no or less behavior....
MiR-34b/c takes an important role in various aspects of carcinogenesis. Notably, pri miR34b/c (rs4938723) T>C polymorphism has been identified as a significant biomarker kinds cancer. The objective this study was to explore whether pri-miR34b/c rs4938723) associated with breast cancer susceptibility. Moreover, the association and clinicopathologic data, including survival outcomes, were studied Thai patients.