A5100644878- Fungal Biology and Applications
- Metabolism, Diabetes, and Cancer
- EEG and Brain-Computer Interfaces
- Medicinal plant effects and applications
- Pneumonia and Respiratory Infections
- Malaria Research and Control
- Lung Cancer Research Studies
- Pharmacological Effects and Assays
- Helicobacter pylori-related gastroenterology studies
- Renal cell carcinoma treatment
- Respiratory viral infections research
- Epilepsy research and treatment
- Diabetes Treatment and Management
- Appendicitis Diagnosis and Management
- Pharmacology and Obesity Treatment
- Neuroscience and Neuropharmacology Research
- Liver Disease Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Polysaccharides and Plant Cell Walls
- Renal and Vascular Pathologies
- Diet, Metabolism, and Disease
Fudan University
2021-2023
Beijing University of Chinese Medicine
2023
Shandong Normal University
2021
Harbin Medical University
2020
Second Affiliated Hospital of Harbin Medical University
2020
Nanjing Brain Hospital
2018
Nanjing Medical University
2018
Obesity is often accompanied by metabolic disorder and insulin resistance, resulting in type 2 diabetes. Based on previous findings, FYGL, a natural hyperbranched proteoglycan extracted from the G. lucidum fruiting body, can decrease blood glucose reduce body weight diabetic mice. In this article, underlying mechanism of FYGL ameliorating obesity-induced diabetes was further investigated both vivo vitro. upregulated expression genes related to fatty acid biosynthesis, β-oxidation...
Protein tyrosine phosphatase 1B (PTP1B) is a key negative regulator of insulin and an effective target for the treatment type 2 diabetes (T2D). A natural hyperbranched proteoglycan extracted from Ganoderma lucidum, namely, Fudan-Yueyang G. Lucidum (FYGL), was demonstrated capable inhibiting activity PTP1B. Here, to identify active components FYGL, three different components, polysaccharide FYGL-1, proteoglycans FYGL-2, FYGL-3, were isolated then, protein moiety FYGL-3 further separated,...
Currently, drugs are limited to treating pediatric pneumonia in clinical practice. It is urgent find one new precise prevention and control therapy. The dynamically changing biomarkers during the development of could help diagnose this disease, determine its severity, assess risk future events, guide treatment. Dexamethasone has been recognized as an effective agent with anti-inflammatory activity. However, mechanisms against remain unclear. In study, spatial metabolomics was used reveal...
Objective We aimed to evaluate the safety and feasibility of delayed appendectomy in treatment acute, nonperforated appendicitis. Methods We collected patients who underwent an for appendicitis between January 2004 February 2013in First People′s Hospital North Forest Region. Patients were divided into 2 groups comparison: immediate group (those moved operating room within 24 hours after hospital arrival) a 48 arrival). The end points operative time, perforation rate, complication...