A5080632931- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Neuroendocrine Tumor Research Advances
- IgG4-Related and Inflammatory Diseases
- MRI in cancer diagnosis
- Gastrointestinal Tumor Research and Treatment
- Appendicitis Diagnosis and Management
- Biliary and Gastrointestinal Fistulas
- Alcohol Consumption and Health Effects
- Liver Disease and Transplantation
- Nanoplatforms for cancer theranostics
- Dermatological and COVID-19 studies
- Neuroblastoma Research and Treatments
- Gastric Cancer Management and Outcomes
- Nanoparticle-Based Drug Delivery
- Abdominal Trauma and Injuries
- Abdominal vascular conditions and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Renal and related cancers
Tokyo Metropolitan Komagome Hospital
2020-2025
Juntendo University
2019-2022
Nagasaki Rousai Hospital
2015
Hamamatsu Rosai Hospital
2009-2010
Radiological evidence of focal pancreatic parenchymal atrophy (FPPA) may presage early ductal adenocarcinoma (PDAC) development. We aimed to clarify the incidence FPPA and clinicopathological features PDAC with before diagnosis. Data on endoscopic ultrasound-guided fine-needle biopsies surgical samples from 170 patients cancer histologically diagnosed between 2014 2019 were extracted pathology database Komagome Hospital Juntendo University hospital retrospectively evaluated together 51...
Background and AimsThe diagnostic performance of EUS-guided fine-needle aspiration/biopsy sampling (EUS-FNAB) for pancreatic ductal adenocarcinoma (PDAC) ≤10 mm in diameter is relatively low. Pancreatic juice cytology (PJC) has gained attention because its high sensitivity small PDACs. We aimed to clarify the ability EUS-FNAB salvage PJC PDAC mm.MethodsData obtained from attempted patients with EUS-confirmed tumors (excluding metastases/malignant lymphomas) were retrospectively analyzed....
Epidermoid cyst in an intrapancreatic accessory spleen (ECIPAS) is a rare, pancreatic cystic lesion covered with epithelioid cells and surrounded by splenic tissue.[1] Most cases of ECIPAS are diagnosed postoperatively based on pathological findings.[2] There few reports contrast-enhanced EUS (CE-EUS) or EUS-FNA. We present herein case CE-EUS A 28-year-old, female patient was admitted cysts. Contrast-enhanced computed tomography revealed 17-mm, multilocular 7-mm, unilocular the tail. The...
Endoscopic ultrasonography (EUS) is used to observe the stricture of main pancreatic duct (MPD) and in diagnosing cancer (PC). We investigate findings on EUS by referring histopathological resected specimens.Six patients with carcinoma situ (CIS) 30 invasive 20 mm or less were included. The preoperative classified as follows. A1: Simple type-no around stricture; A2: Hypoecho type-localized hypoechoic area without demarcation A3: Tumor type-tumor B: Dilation type-the dilation a downstream C:...
We report that an oblique-viewing endoscope facilitates endoscopic retrograde cholangiopancreatography (ERCP) in Billroth II reconstruction. With this endoscope, we carried out ERCP Roux-en-Y reconstruction.Fifteen patients with reconstruction were enrolled. Eleven of these had undergone gastrectomy, while Whipple's operation or choledochectomy each been two patients. Among the 11 post-gastrectomy patients, eight bile duct stones, and there was one case pancreatic abscess chronic...
Stenotic pancreatico‐enteric anastomosis is one of the serious late complications after a pancreaticoduodenectomy. We report case stenotic pancreaticojejunostomy with pancreatic juice fistula drained externally, which was treated using percutaneous procedures combined rendezvous method. A 77‐year‐old woman referred to our hospital for an endoscopic treatment remove drainage tube from fluid collection due fistula. She had undergone pylorus‐preserving pancreatoduodenectomy Roux‐en‐Y...
Abstract Intraductal oncocytic papillary neoplasm (IOPN) is a rare intraductal tumor of the pancreatobiliary system. Currently, little known about its distinct characteristics, unlike mucinous neoplasms (IPMN) and bile duct (IPNB). The present study compared 22 IOPNs (18 pancreatic 4 biliary) with those 61 IPMNs/8 IPNBs. were classified into pure combined types, depending on coexistence IPMN/IPNB. Multiple gene expression analysis (nCounter system) was performed, hierarchical clustering...
Objectives This study aimed to assess the pitfalls of current International Association Pancreatology guidelines (IAPCG2017) for pancreatic intraductal papillary mucinous neoplasm (IPMN) and identify criteria future guidelines. Methods Eighty surgically resected, consecutive IPMN cases were analyzed. Data including tumor site, duct type, surgery type collected. Based on radiological data, retrospectively classified as high-risk stigmata (HRS) non-HRS. Pathological grades histological...
Gallbladder (GB) wall thickening sometimes occurs in patients with autoimmune pancreatitis (AIP), a condition for which the name, IgG4-related cholecystitis, was proposed. We examined radiological findings of GB diseases and clinical features presented hypothesis its pathogenesis.GB defined by thickness ≥ 4 mm. 258 disease. Clinical imaging 200 AIP without were then compared.GB detected 58 (29%) two isolated sclerosing cholangitis. In 60 GBs examined, diffuse, walls possessing smooth inner...
A 59-year-old woman presented with a chief complaint of melena. She had no abdominal findings, such as tenderness or tapping pain. Laboratory tests revealed white blood cell count 5,300 cells/μL and C-reactive protein level 0.07 mg/dL. Inflammation anemia (hemoglobin 12.4 g/dL) were denied. Contrast-enhanced computed tomography (CT) multiple duodenal diverticula air surrounding descending diverticulum. Based on these diverticular perforation (DDP) was suspected. Oral food intake stopped,...
Ryota Sagami, Kentaro Yamao, Ryuki Minami, Jun Nakahodo, Hidetoshi Akiyama, Hidefumi Nishikiori, Kazuhiro Mizukami, Kenji Vikram Bhatia, Yuji Amano, and Kazunari Murakami. Gut Liver -0001;0:. https://doi.org/10.5009/gnl220521
A 46-year-old female patient was referred to our hospital for endoscopic treatment of stenotic pancreatogastrostomy. She had undergone pylorus-preserving pancreatoduodenectomy due duodenal carcinoma the papilla Vater 5 years before referral. Two after operation, she be hospitalized several times during a 1-year period because acute recurrent pancreatitis caused by stenosis anastomosis pancreatoduodenostomy. An ultrasound (EUS)-guided rendezvous technique selected puncture main pancreatic...
Intraductal papillary neoplasms of the bile duct (IPNB) are histologically and clinically classified as type 1 2. This study aimed to identify differences between these two types.Based on multiple gene expression analysis (MGEA) using 1, 2, pancreatic intraductal mucinous (n=4, 6, 5, respectively), immunohistochemistry DNMT1 methylation-specific PCR for p16, APC, BRCA1, hMLH1, TIMP3, SOX17 were performed 2 IPNBs (n=14, each).The protein was highly expressed (p<0.001) in 28.6% cases all...
While autoimmune pancreatitis (AIP) responds well to steroid therapy, the high relapse rate in type 1 AIP remains a critical problem. The present study examined predictors of following therapy.
Background/Aim: We previously reported the usefulness of detecting aberrant methylation in tumor suppressive microRNAs (miRNAs) bile and plasma to discriminate pancreaticobiliary cancers from benign diseases. This study analyzed miRNAs pancreatic juice identify those specific cancer (PC). Patients Methods: Pancreatic was collected 20 patients with PC, including eight intraductal papillary mucinous carcinoma (IPMC), two low grade-pancreatic intraepithelial neoplasia (LG-PanIN), 32...
To improve the poor prognosis of pancreatic ductal adenocarcinoma (PDAC), diagnosis early-stage PDAC is essential. In particular, high-grade intraepithelial neoplasia/carcinoma in situ (HG-PanIN/CIS) best option. However, it almost impossible to directly observe HG-PanIN/CIS. Thus, identifying a secondary imaging finding due disorder important. Focal parenchymal atrophy (FPPA) and hypoechoic area have been reported as preferred signs. We studied 50 patients clarify effectiveness FPPA...