- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Anesthesia and Sedative Agents
- Spinal Cord Injury Research
- Cardiovascular Syncope and Autonomic Disorders
- Pain Management and Opioid Use
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Obstructive Sleep Apnea Research
- Medical Practices and Rehabilitation
- Nausea and vomiting management
- Pathogenesis and Treatment of Hiccups
- Opioid Use Disorder Treatment
- Cardiac Arrest and Resuscitation
- Veterinary Pharmacology and Anesthesia
- Biomedical and Chemical Research
- Anatomy and Medical Technology
- Liver Disease and Transplantation
- Ion channel regulation and function
- Intensive Care Unit Cognitive Disorders
- Cardiac electrophysiology and arrhythmias
- Head and Neck Surgical Oncology
- Intraocular Surgery and Lenses
- Healthcare Decision-Making and Restraints
- Renal function and acid-base balance
Universitäre Psychiatrische Dienste Bern
2020-2023
Swiss Paraplegic Center
2002-2022
Swiss Paraplegic Research
2002-2017
Université Libre de Bruxelles
2013
Marienkrankenhaus Hamburg
2002-2005
University of Vienna
1998-2005
Pain and Rehabilitation Medicine
2002-2003
Wipro (Singapore)
2002
Abstract Background Infections are a leading cause of death in patients with advanced cirrhosis, but there relatively few data on the epidemiology infection intensive care unit ( ICU ) cirrhosis. Aims We used from Extended Prevalence Infection Intensive Care EPIC II 1‐day point‐prevalence study to better define characteristics these patients. Methods compared characteristics, including occurrence and types infections non‐cirrhotic cirrhotic who had not undergone liver transplantation....
Abstract Background The objective of this study is to assess the impact dysnatraemia on mortality among intensive care unit ( ICU ) patients in a large, international cohort. Material and methods Analysis E xtended P revalence I nfection ntensive C are EPIC II study, 1‐day (8 M ay 2007) worldwide multicenter, prospective point prevalence study. Hyponatraemia was categorized as mild (130–134 mM/L), moderate (125–129 mM/L) or severe (< 125 mM/L). Hypernatraemia also (146–150 (151–155 (>...
Prospective cohort study.To investigate the changes in resting energy expenditure and body composition over time a of patients with spinal cord injury during acute treatment, rehabilitation, 2 years after end rehabilitation.Adult admitted for treatment rehabilitation traumatic were recruited. Measurements scheduled at 2, 6, 10 14 weeks injury, later.Patients' mean age was 38.8 (standard deviation 14.0). Resting began to decrease up 10-week measurement (p = 0.02) further decreased 130-week...
A retrospective cohort study.To examine the differences in use of methylprednisolone protocol for traumatic spinal cord injury before and after publication new guidelines Switzerland.The changed guidelines. The rate physicians prescribing high-dose patients with acute was studied. Two intervals, each comprising 24 months consensus article Switzerland, were compared. As a secondary parameter, neurological development during rehabilitation period compared.The charts all adult who referred...
A 39-year-old patient developed phantom pain after amputation of both upper arms following a burn injury. The did not respond to naproxen, morphine, carbamazepine, amitriptyline, calcitonin or transcutaneous electrical nerve stimulation (TENS). At the 39th post-operative day an axillary catheter was placed on right side, as well interscalene left. Ropivacaine 0.2% infused, starting with rate 4 ml/h, that increased 6 ml/h during subsequent days. Within 20 min placement complete relief...
Standardization of the in vitro contracture test (IVCT) for malignant hyperthermia (MH) susceptibility has resulted very rare false negative tests. However, positive results stigmatizing patient seem to be more frequent than and make supplementary tests desirable. This multicenter approach studied usefulness an IVCT with 4-chloro-m-cresol (4-CmC), a ryanodine receptor-specific agonist better definition MH susceptibility. Diagnosis made by standard was compared this 4-CmC on muscle specimens...
Remifentanil offers a wide range of clinical uses and has been successfully combined with general anesthetics. However, there are few human experimental studies demonstrating the analgesic property remifentanil. It was our aim to determine effect remifentanil regard dose-dependent increments in model heat pain threshold assessment. Twenty healthy volunteers were randomized double-blinded cross-over design receive an infusion or saline. The stepped increased every 5 min by 0.01 μg · kg−1...
A retrospective analysis of the effects electroconvulsive therapy (ECT) was performed for two groups 11 patients matched according to age (mean age, 52 years), sex, and diagnosis. Group 1 received ECT age-dose protocol; group 2 treated titration method. higher dose relative seizure threshold appeared shorten duration. At first treatment, correlation between stimulus intensity duration negative. In group, initial mean charge 91 mC resulted in a 51 s, whereas 31 s significantly shorter despite...
In recent years, new minimally invasive therapies for the treatment of radicular pain associated with contained disc herniation have been introduced. These techniques changed field interventional management. a prospective, nonrandomized case study, we treated patients using Dekompressor system guided by computed tomography instead fluoroscopy. Pain scores, analgesic usage, and activities daily living were assessed via structured telephone interviews 6 12 months after procedure. Sixty-four at...
Background and purpose Analgesics can have undesirable effects. We assessed whether a single preoperative dose of 120 mg etoricoxib reduces the need for additional opioids after therapeutic arthroscopic knee surgery.Methods A double-blind, placebo-controlled study was performed at center. 66 patients scheduled to undergo elective arthroscopy were included. They randomly selected be given either (n = 33) or placebo 1 hour before induction general anesthesia. patient-controlled analgesia...
Chronic hiccups may be a serious therapeutic problem. Pharmacological treatment with increasing dosages of baclofen, carbamazepine, or gabapentin is not always successful. In this paper, the use general anesthesia positive-pressure ventilation and muscle relaxation for termination chronic described.
Background and objective: Epidural blocks should provide good analgesia for the treatment of chronic low back pain without any motor block to allow active physiotherapy. ropivacaine is known produce less compared bupivacaine at anaesthetic concentrations. This prospective, randomized double blind study compares analgesic, block, haemodynamic effects single shot epidural injections 0.2% 10 mL with 0.125% in outpatients suffering from pain. Methods: Forty patients were assigned receive either...
Background and objective: Epidural blocks should provide good analgesia for the treatment of chronic low back pain without any motor block to allow active physiotherapy. ropivacaine is known produce less compared bupivacaine at anaesthetic concentrations. This prospective, randomized double blind study compares analgesic, block, haemodynamic effects single shot epidural injections 0.2% 10 mL with 0.125% in outpatients suffering from pain. Methods: Forty patients were assigned receive either...
Background and objective: The in vitro contracture test with halothane caffeine is the gold standard for diagnosis of susceptibility to malignant hyperthermia (MH). However, sensitivity between 97 99% its specificity 78-94% consequence that false-negative as well false-positive results are possible. 4-Chloro-m-cresol potentially a more specific drug than or caffeine. This multicentre study was designed investigate whether an bolus administration 4-chloro-m-cresol can improve accuracy MH....
SummaryBackground and objective: The in vitro contracture test with halothane caffeine is the gold standard for diagnosis of susceptibility to malignant hyperthermia (MH). However, sensitivity between 97 99% its specificity 78–94% consequence that false-negative as well false-positive results are possible. 4-Chloro-m-cresol potentially a more specific drug than or caffeine. This multicentre study was designed investigate whether an bolus administration 4-chloro-m-cresol can improve accuracy...
Hiccups are repeated abrupt contractions of the diaphragm and external intercostal muscles. The glottis closes to prevent inspiration 35 ms after electrical activity rises above baseline in muscles (1). Usually hiccups terminate spontaneously within hours, but they may also persist for longer lead serious therapeutic problems (2). Case Report A 60-yr-old patient presented our medical department suffering from 3 days. did not respond simple measures, such as drinking cold fluids, holding...
Remifentanil offers a wide range of clinical uses and has been successfully combined with general anesthetics. However, there are few human experimental studies demonstrating the analgesic property remifentanil. It was our aim to determine effect remifentanil regard dose-dependent increments in model heat pain threshold assessment. Twenty healthy volunteers were randomized double-blinded cross-over design receive an infusion or saline. The stepped increased every 5 min by 0.01 μg · kg−1...
To the Editor: We read with interest article by Barker and Polson (1). too consider a plan for possible emergencies during operations to be infinitely important can only endorse Barkers Polson’s recommendations. An intratracheal fire represents an unusual but nevertheless complication laser surgery in tracheobronchial system (2–6). The incidence of respiratory tract is stated as being between 0,4% 1,5%(7). A should therefore place avoid this catastrophic complication, or, event (2,6)....