A5055620389- Ferroptosis and cancer prognosis
- Thyroid Cancer Diagnosis and Treatment
- Hormonal Regulation and Hypertension
- ATP Synthase and ATPases Research
- Cancer Mechanisms and Therapy
- Thyroid Disorders and Treatments
- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism
- Flavonoids in Medical Research
- Helicobacter pylori-related gastroenterology studies
- Drug-Induced Hepatotoxicity and Protection
- Cancer-related gene regulation
- Pelvic floor disorders treatments
- Intracranial Aneurysms: Treatment and Complications
- RNA modifications and cancer
- Bacteriophages and microbial interactions
- Retinoids in leukemia and cellular processes
- Cancer Cells and Metastasis
- Animal Genetics and Reproduction
- Phytochemistry and biological activity of medicinal plants
- Enzyme Production and Characterization
- Cardiovascular and Diving-Related Complications
- Estrogen and related hormone effects
- Cancer Research and Treatments
- Ion Transport and Channel Regulation
Qinghai University
2021-2025
Capital Medical University
2017-2023
Beijing Friendship Hospital
2023
Beijing Anzhen Hospital
2018
Beijing Hospital of Traditional Chinese Medicine
2017-2018
Beijing University of Chinese Medicine
2017
Huazhong University of Science and Technology
2004
Taraxacum officinale, a traditional medicinal herb, has garnered significant attention for its potential role in the prevention and treatment of breast cancer. Although clinical recognition efficacy gradually increased, research shown that officinale contains variety chemical components, including triterpenes, carbohydrates, flavonoids, phenolic acids, sesquiterpenes, coumarins, fatty organic acids. However, pharmacological mechanisms underlying officinale's effects identification key...
Fisetin, a natural flavonoid found in variety of edible and medical plants, has been suggested to inhibit the proliferation various tumor cells induce apoptosis. However, effects fisetin on breast cancer have rarely reported underlying mechanism is still undefined. The present study explored anti‑cancer mammary carcinoma mechanisms. Following treatment with fisetin, viability 4T1, MCF‑7 MDA‑MB‑231 were measured by MTT assay. inhibitory proliferation, migration invasion evaluated 4T1 using...
It has been documented that over-expression of metastasis-associated in colon cancer-1 (MACC1) is related to poor prognosis non-small cell lung cancer (NSCLC).This study investigates the function and underlying molecular mechanisms MACC1 adenocarcinoma.Here, we firstly employed immunohistochemistry, western blotting, real-time PCR, online database demonstrate expression was elevated tumor tissues compared with tumoradjacent or normal tissues.Real-time CCK-8, colony formation Hoechst...
Objective: To investigate the relationship between miR-199b and clinicopathologic features prognosis of patients with colorectal cancer. Methods: Cancer tissues adjacent normal 202 cancer treated in Hospital Chinese Academy Medical Sciences from March to December 2011 were collected. Reverse transcription-quantitative real-time polymerase chain reaction was used detect expression level corresponding tissues. Kaplan-Meier method Log rank test for survival analysis, receiver operating...
Overexpressed gastrin is reported to promote oncogenesis and development of gastric cancer by inhibiting apoptosis cells; however, the underlying mechanism remains unclear. Our study aimed at revealing effect on cells. Gastrin-interfering cell line was constructed stably transfecting gastrin-specific pshRNA plasmid BGC-823. Then, differentially expressed proteins between untreated BGC-823 gastrin-interfering lines were detected iTRAQ technique. GO KEGG analysis used analyze genes that code...
Gastrin plays a vital role in the development and progression of gastric cancer (GC). Its expression is up-regulated GC tissues several cell lines. Yet, underlying mechanism remains to be investigated. Here, we aim investigate gastrin proliferation. Gastrin-overexpressing model was constructed using SGC7901 cells. Then differentially expressed proteins were identified by iTRAQ analysis. Next, use flow cytometry immunofluorescence study effect on mitochondrial potential mitochondria-derived...
The purpose of this study was to investigate the mechanism action muscone on breast cancer using network pharmacology and molecular docking techniques.Targets acid were collected PubChem SwissTargetPrediction databases. Relevant target sets GeneCards database, intersection drug-disease targets used as potential in cancer. STRING database construct a protein-protein interaction (PPI) network, data imported into Cytoscape 3.7.1 for topological analysis obtain core genes Gene Ontology (GO)...
Objective: To evaluate the long-term efficacy of treatments on cryptogenic ischemic cerebral vascular disease (CICVD) with patent foramen ovale (PFO) and analyze prognostic factors, so as to provide references for treatment secondary prevention PFO related disease. Methods: Consecutive patients CICVD right-to-left shunting confirmed by transesophageal echocardiography or transcranial doppler bubble test, who admitted Department Neurology in Xuanwu Hospital from May 1, 2012 December 31 2021...
Abstract Eukaryotic Elongation Factor 1 Alpha 2 (EEF1A2) is a protein coding gene which involved in tumor development and progression several types of human cancer, but little known about the function EEF1A2 proteins gastric cancer (GC).The ONCOMINE TCGA databases were used to evaluate expression GUF1 , EFTUD2 GSPT1 GSPT2 GC association family with individual clinical characteristics. Kaplan-Meier (K-M) Plotter hint prognostic value . GSE62254 GSE66222 dataset validated Human AGS GES cells...