A5028208163- Graphene and Nanomaterials Applications
- Carbon and Quantum Dots Applications
- Advanced Nanomaterials in Catalysis
- Wound Healing and Treatments
- Bone Tissue Engineering Materials
- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Nanoparticles: synthesis and applications
- Electrospun Nanofibers in Biomedical Applications
- HER2/EGFR in Cancer Research
- Dielectric properties of ceramics
- Hydrogels: synthesis, properties, applications
- Biosensors and Analytical Detection
- Advanced Drug Delivery Systems
- Inhalation and Respiratory Drug Delivery
- Heavy Metal Exposure and Toxicity
- Nanofabrication and Lithography Techniques
- Neurological Disorders and Treatments
- Synthesis and biological activity
- SARS-CoV-2 detection and testing
- Proteoglycans and glycosaminoglycans research
- Tissue Engineering and Regenerative Medicine
- Inflammation biomarkers and pathways
- biodegradable polymer synthesis and properties
- Nerve injury and regeneration
Banaras Hindu University
2021-2025
Indian Institute of Technology BHU
2021-2024
In this work, mesoporous (pore size below 4 nm) composite nanoparticles of ZnO-Ag2O/Ag, ZnO-CuO, and ZnO-SnO2 d ≤ 10 nm (dia.) have been synthesized through the in situ solvochemical reduction method using NaBH4. These exhibited excellent killing efficacy against Gram-positive/negative bacterial fungal strains even at a very low dose 0.010 μg/mL. Additionally, by applying silico docking approach, microorganism-specific targeted proteins their interactions identified to explain best...
p(NAG- co -Ac) shows potential anticancer properties in heparanase-driven invasive malignancies without using additional drugs.
Glycine-based polymer nanoparticles for the treatment of inflammatory diseases without using any additional drugs.
The OTDDN library of amphiphilic copolymer [p(NAG- co -NAPA) ( x : y ) ] NPs with multiple drugs is effective for treating TNBC. Further, this has presented exciting treatment options specific organs such as liver, heart, lungs, and kidneys.
Invasive bacterial and fungal infections have notably increased the burden on health care system especially in immune compromised patients. These invasive species mimic interact with host extracellular matrix increase adhesion internalization into system. Further, resistance of traditional antibiotics/antifungal drugs led to demand for other therapeutics preventive measures. Presently, metallic nanoparticles wide applications sectors. The present study has been designed evaluate advantage Ag/Sn-SnO
In this work, the glycine-based acryloyl monomer is polymerized to obtain a neurogenic polymeric hydrogel for regenerative applications. The synthesized poly(N-acryloylglycine-acrylamide) [poly(NAG-b-A)] nanohydrogel exhibits high swelling (∼1500%) and mechanically very stable, biocompatible, proliferative in nature. poly(NAG-b-A) provides stable 3D extracellular mimetic environment promotes healthy neurite growth primary cortical neurons by facilitating cellular adhesion, proliferation,...
In this era of advanced technology and innovation, infectious diseases still cause significant morbidity mortality, which need to be addressed. Despite overwhelming success in the development vaccines, transmittable such as tuberculosis AIDS remain unprotected, treatment is challenging due frequent mutations pathogens. Formulations new or existing drugs with polymeric materials have been explored a promising approach. Variations shape, size, surface charge, internal morphology,...
The wound-healing process is highly coordinated and regulated interactions between the immune biological systems since long-term wounds are severe clinical issues which make patients vulnerable to potentially fatal microbial infections.
Endogenous gasotransmitter nitric oxide (NO) is a central signalling molecule that modulates wound healing by maintaining homeostasis, collagen formation, contraction, anti-microbial action and accelerating tissue regeneration. The optimum delivery of NO using nanoparticles (NPs) clinically challenging; hence, it drawing significant attention in healing. Herein, novel polymeric nanoplatform loaded with sodium nitroprusside (SP) NPs was prepared used for to obtain the sustained release...
[p(NAG-Ac-NAE)] mimic cellular microenviroment by facilitating neuronal stem cell migration towards the injured site via aniogenesis and induce recovery.
In this work, a series of mesoporous carbon nanocapsules (mCNS) size below 10 nm have been prepared from Azadirachta indica seeds with very easy and cost-effective approach. These can emit red green light are effective for cell imaging. Further, these biocompatible toward the normal healthy cells, however, they possess modest cytotoxicity against MCF-7 (human breast cancer) triple-negative cancer (TNBC) (MDA- MB-231 cells), rate killing cells strongly depends on dose mCNCs. mitochondrial...
There are a notable advancement in the technology associated with using waste resources to create novel and beneficial products. It was demonstrated that Azadirachta indica kernel component, also known...
A facile cost-effective green synthesis approach has been used to synthesize carbon-dot (CDs) from the Kernel part of