Laurie Twells

ORCID: 0000-0003-1447-9203
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About
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Research Areas
  • Bariatric Surgery and Outcomes
  • Obesity and Health Practices
  • Breastfeeding Practices and Influences
  • Child Nutrition and Feeding Issues
  • Body Contouring and Surgery
  • Obesity, Physical Activity, Diet
  • Diabetes Treatment and Management
  • Maternal Mental Health During Pregnancy and Postpartum
  • Diabetes Management and Research
  • Pharmacology and Obesity Treatment
  • Clinical practice guidelines implementation
  • Diet and metabolism studies
  • Gastric Cancer Management and Outcomes
  • Health Systems, Economic Evaluations, Quality of Life
  • Metabolism, Diabetes, and Cancer
  • Health Promotion and Cardiovascular Prevention
  • Atrial Fibrillation Management and Outcomes
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Mental Health and Patient Involvement
  • Cardiovascular Disease and Adiposity
  • Child and Adolescent Health
  • Birth, Development, and Health
  • Infant Nutrition and Health
  • Diabetes Management and Education
  • Healthcare Policy and Management

Memorial University of Newfoundland
2016-2025

Health Sciences Centre
2013-2018

St. John's School
2017

St. John’s Health Sciences Centre
2017

Eastern Health
2017

St. John's University
2014

Memorial
2008

<h3>Background</h3> The prevalence of obesity has increased over the past 3&nbsp;decades, with a disproportionate growth in excessive weight categories (body mass index [BMI] 35.0–39.9 and BMI ≥ 40.0). objective this paper is to present data for current adult Canada, together future estimates. <h3>Methods</h3> We calculated BMIs adults aged 18 years older who were not long-term care using from Canadian health surveys administered between 1985 2011. Calculation was based on self-reported...

10.9778/cmajo.20130016 article EN CMAJ Open 2014-03-03

People with diabetes may be at higher risk for acquiring infections through both glucose-dependent and biologic pathways independent of glycemic control. Our aim was to estimate the association between occurring in primary care.Using Newfoundland Labrador Sentinel Canadian Primary Care Surveillance Network, patients ≥18 years 1 January 2008 31 March 2013 were included least 1-year follow-up. We randomly matched each patient on date study entry up 8 controls without diabetes. outcome...

10.1186/s12879-018-2975-2 article EN cc-by BMC Infectious Diseases 2018-02-05

The beneficial outcomes of oral anticoagulation therapy are dependent upon achieving and maintaining an optimal INR therapeutic range. There is growing evidence that better achieved when managed by a pharmacist with expertise in management rather than usual care family physicians. This study compared program (PC) to physician (UC) medicine clinic. A retrospective cohort was carried out clinic which included clinical pharmacist. In 2006, the assumed management. For 17-month period, PC group...

10.1186/1471-2296-12-88 article EN cc-by BMC Family Practice 2011-08-17

Childhood obesity is a public health problem in Canada. Accurate measurement of crucial defining its burden. The objective this study to compare the prevalence estimates overweight and preschool children using three growth references. Weights heights were measured on 1026 born Newfoundland Labrador (NL), Canada, body mass index calculated. was determined statistical comparisons conducted among references; Centres for Disease Control (CDC), International Obesity Task Force (IOTF) World Health...

10.1186/1471-2431-11-21 article EN cc-by BMC Pediatrics 2011-02-28

Vitamin D deficiency is associated with poor bone health, colorectal cancer, type 1 diabetes and multiple sclerosis.Two national health-related societies in Canada have made recommendations for vitamin supplementation, yet little research has been reported on the status of Canadians.Lifestyle changes, such as sunscreen use, spending less time outdoors insufficient intake D-containing foods well northern latitude, may be affecting human status.A cross-sectional analysis 25-hydroxyvitamin...

10.1111/j.1740-8709.2008.00157.x article EN Maternal and Child Nutrition 2008-11-27

Purpose: Infant feeding differences are strongly tied to socioeconomic status. The goal of this study is compare determinants early breastfeeding cessation incidence in socioeconomically marginalized (SEM) and privileged (SEP) populations, focusing on birthing parents who intended breastfeed. Methods: This cohort includes data from 451 the Canadian province Newfoundland Labrador reported intention breastfeed baseline prenatal survey. Multivariate logistic regression techniques were used...

10.1089/heq.2016.0028 article EN cc-by Health Equity 2017-06-06

Breastfeeding has numerous health benefits. In 2010, the province of Newfoundland and Labrador had lowest breastfeeding initiation rate (64.0%) in Canada. Formula feeding is associated with well-known risks. Exclusive formula "cultural norm" some regions province. Women appear resistant to changing their infant behaviors remain committed decision formula-feed. The primary aim this qualitative study was examine individual factors that shaped mothers' decisions formula-feed infants. Nineteen...

10.1186/1471-2458-13-645 article EN cc-by BMC Public Health 2013-07-12

In Canada waiting lists for bariatric surgery are common, with wait times on average > 5 years. The meaning of from the patients' perspective must be understood if health care providers to act as facilitators in promoting satisfaction and quality outcomes. aims this study were explore perceptions surgery, experience waiting, psychosocial behavioral impact treatment identify provider system supportive measures that could potentially improve experience. Twenty-one women six men engaged...

10.1186/1475-9276-12-86 article EN cc-by International Journal for Equity in Health 2013-01-01

Breast feeding provides protection from many diseases and reduces health risks for both mother child; however, a significant percentage of mothers in Newfoundland Labrador, Canada choose to formula feed their infants birth. In order understand this phenomenon, qualitative research the form focus groups was conducted three communities province 2010. The data elicited question 'Why did you your baby?' were analysed using thematic content analysis. A major theme that arose how these women...

10.1080/13698575.2012.662635 article EN Health Risk & Society 2012-03-26

Maternal attitudes to infant feeding are predictive of intent and initiation breastfeeding.The Iowa Infant Feeding Attitude Scale (IIFAS) has not been validated in the Canadian population. This study was conducted Newfoundland Labrador, a province with low breastfeeding rates. Objectives were assess reliability validity IIFAS expectant mothers; compare urban rural areas; examine whether associated breastfeed.The assessment tool administered 793 pregnant women. Differences total scores...

10.1177/0890334414559647 article EN Journal of Human Lactation 2014-11-25

Introduction Weight loss is often recommended as the primary intervention for infertility in individuals with high body mass index. However, focusing on index might overlook other important factors like cardiometabolic health. This study aims to examine health patients seeking fertility treatment and its impact reproductive outcomes. Methods analysis A cross-sectional of 800 systematically selected participants (400 couples) will be completed a single visit site. session involve taking blood...

10.1136/bmjopen-2024-093704 article EN cc-by-nc-nd BMJ Open 2025-04-01

Objectives To compare population-based incidence rates of new-onset depression or self-harm in patients initiating incretin-based therapies with that sulfonylureas (SU) and other glucose-lowering agents. Design Population-based cohort study. Setting Patients attending primary care practices registered the UK-based Clinical Practice Research Datalink (CPRD). Participants Using CPRD, we identified two cohorts: (1) dipeptidyl peptidase-4 inhibitor (DPP-4i)-cohort, consisting new users DPP-4i SU...

10.1136/bmjopen-2018-023830 article EN cc-by-nc BMJ Open 2018-10-01

Mixed evidence exists for the effect of incretin-based therapies on osteoporosis in type-2 diabetes. Therefore, we conducted a cohort study to determine association between dipeptidyl peptidase-4 (DPP-4) inhibitors and common osteoporotic "fragility fractures" (upper extremity, hip, spine).The UK-based Clinical Practice Research Datalink was used identify adults without prior fractures receiving new anti-diabetic drug or diabetes diagnosis 2007 2016. The primary aim compare new-users DPP-4...

10.1016/j.diabres.2017.12.008 article EN cc-by-nc-nd Diabetes Research and Clinical Practice 2017-12-16

A pharmacist managed anticoagulation service was initiated in a multi-physician family medicine clinic December 2006. In order to determine the patient and physician satisfaction with service, study designed describe patients' warfarin education management they received from pharmacist, physicians' level of care provided by for patients taking warfarin. self-administered survey completed both eligible receiving physicians prescribing between 2006 May 2008. The collected information on...

10.1186/s13104-015-1187-8 article EN cc-by BMC Research Notes 2015-06-09

Background and Aim . Obesity is associated with an increased risk of cardiovascular disease may be more severe coronary artery (CAD); however, the relationship between body mass index [BMI (kg/m 2 )] CAD severity uncertain debatable. The aim this study was to examine BMI angiographic CAD. Methods Duke Jeopardy Score (DJS), a prognostic tool predictive 1-year mortality in CAD, assigned data patients ≥18 years age (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...

10.1155/2017/5481671 article EN cc-by Cardiology Research and Practice 2017-01-01

Newfoundland and Labrador (NL) has the highest rate of obesity in Canada, prompting establishment a bariatric surgery program at Health Sciences Centre NL. This retrospective study examined 30-day complication rates more than 200 consecutive patients who underwent laparoscopic sleeve gastrectomy (LSG) between May 2011 February 2014.We performed chart review collected data on postoperative complications. Complications were graded reported using Clavien-Dindo classification. Grades I II...

10.1503/cjs.016815 article FR Canadian Journal of Surgery 2016-03-31
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