Zhexuan Yu

ORCID: 0000-0003-1452-0704
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Research Areas
  • Mechanical Circulatory Support Devices
  • Esophageal Cancer Research and Treatment
  • Allergic Rhinitis and Sensitization
  • Cardiac Structural Anomalies and Repair
  • Cardiac Arrest and Resuscitation
  • Cardiac Ischemia and Reperfusion
  • Infection Control and Ventilation
  • Estrogen and related hormone effects
  • Inflammatory mediators and NSAID effects
  • COVID-19 and healthcare impacts
  • Neonatal and fetal brain pathology
  • Electric Power System Optimization
  • Neonatal and Maternal Infections
  • Liver Disease Diagnosis and Treatment
  • Sepsis Diagnosis and Treatment
  • Infrastructure Maintenance and Monitoring
  • Aortic Disease and Treatment Approaches
  • Traditional Chinese Medicine Analysis
  • Hepatitis B Virus Studies
  • Traditional Chinese Medicine Studies
  • Innovative concrete reinforcement materials
  • Ginseng Biological Effects and Applications
  • Optimal Power Flow Distribution
  • Radiopharmaceutical Chemistry and Applications
  • Cardiac and Coronary Surgery Techniques

Zhejiang Chinese Medical University
2020-2024

Beijing Tongren Hospital
2008-2022

Capital Medical University
2007-2022

South China University of Technology
2021

Nanchang University
2019

Peking University Shougang Hospital
2015

Essen University Hospital
2008

Beijing Friendship Hospital
2008

Introduction: Septic cardiomyopathy is a sepsis-mediated cardiovascular complication with severe microcirculatory malperfusion. Emerging evidence has highlighted the protective effects of pulsatile flow in case disturbance, yet underlying mechanisms are still elusive. The objective this study was to investigate N6-methyladenosine (m 6 A) modification alleviation septic associated extracorporeal membrane oxygenation (ECMO)-generated flow. Methods: Rat model established and supported under...

10.1097/js9.0000000000001402 article EN cc-by-nc-nd International Journal of Surgery 2024-03-28

There is a universally accepted view that environmental pollution should be controlled while improving cement mortar natural abilities. The purpose of this study to develop green has better compressive strength and anti-chloride ion permeability. Two industrial wastes, lithium-slag slag, were added mortar, the role was activate slag. In addition, save economic time costs, paper also used least-squares support vector machine (LS-SVM) method predict property changes cementitious-based...

10.3390/ma12101652 article EN Materials 2019-05-21

Objective: To investigate the incidence and clinical features of retinopathy prematurity (ROP) among preterm infants in a neonatal intensive care unit (NICU) Lhasa, to explore screening criteria for ROP high-altitude areas. Methods: It was single-center retrospective case study. A total 166 Tibetan ethnicity admitted NICU Lhasa People's Hospital from May 1, 2020 June 2022 with gestational age<36 weeks were enrolled. screened using third-generation wide-angle digital pediatric retinal imaging...

10.3760/cma.j.cn112142-20250102-00003 article EN PubMed 2025-05-11

Severe microcirculatory disturbance is common in patients with cardiogenic shock necessitating extracorporeal membrane oxygenation (ECMO), however, biomarkers linked to microcirculation and clinical outcome are scarce. Herein we identified a circular RNA, hsa_circ_0007367, rooted from the ubiquitin-associated protein 2 (UBAP2) gene, namely circUBAP2, evaluated its biological function associations prognosis.Patients on ECMO were included if qualified sublingual parameters could be obtained...

10.1097/shk.0000000000001937 article EN Shock 2022-06-01

To investigate cyclooxygenase-2 (COX-2) mRNA expression in human esophageal squamous cell carcinoma and the effect of a non-steroidal anti-inflammatory drug (NSAID) on it, order to explore mechanism COX-2 (ESCC) carcinogenesis ability NSAID prevent or treat ESCC. Frozen specimens ESCC adjacent normal epithelium pairs (n = 22) were examined for by reverse-transcription polymerase chain reaction (RT-PCR). After incubation with aspirin (a non-selective COX inhibitor) Nimesulide selective...

10.1111/j.1442-2050.2007.00697.x article EN Diseases of the Esophagus 2007-05-15

The impairment of microcirculation is associated with the unfavorable outcome for extracorporeal membrane oxygenation (ECMO) patients. Studies revealed that pulsatile modification improves hemodynamics and attenuates inflammation during ECMO support. However, whether flow pattern impacts endothelial integrity rarely documented. objective this work was to explore how pulsatility affects ECMO. Canine animal models cardiac arrest were supported by ECMO, i-Cor system used generate nonpulsatile...

10.1155/2022/1630918 article EN cc-by Oxidative Medicine and Cellular Longevity 2022-02-18

Background About 20%–40% of patients diagnosed with ductal carcinoma in situ (DCIS) by core needle biopsy (CNB) will develop invasive cancer at the time excision. Improving preoperative diagnosis DCIS is important for surgical planning. Purpose To establish an MRI‐based radiomics nomogram preoperatively evaluating upstaging and help risk stratification. Study Type Retrospective. Population A total 227 (50.5 ± 9.7 years; 67 upstaged DCIS) were divided into training ( n = 109), internal 47),...

10.1002/jmri.28539 article EN Journal of Magnetic Resonance Imaging 2022-11-28

The objective of this study is to investigate the effects aspirin and nimesulide on cell proliferation, apoptosis its potential mechanisms in EC9706 EC109 esophageal squamous carcinoma cells. cells were incubated with varying concentrations nimesulide, proliferation monitored by 3-(4,5-dimethyl-thiazol-2yl)-2,5-diphenyltetrazolium bromide flow cytometry. Reverse transcription-polymerase chain reaction Western blot assays used expression Bcl-2 Bax. Prostaglandin E2 production was measured...

10.1111/j.1442-2050.2008.00836.x article EN Diseases of the Esophagus 2008-06-17

The etiology of Bell's palsy (BP) is currently unknown, and the findings from previous studies examining association between seasonal or meteorological factors BP have been inconsistent. This research aims to clarify this relationship by analyzing a larger dataset employing appropriate statistical methods. Data 5387 patients with treated at Zhejiang Provincial Hospital Traditional Chinese Medicine in Hangzhou, Province, May 1, 2018, June 30, 2023, was gathered. We assessed temporal...

10.1038/s41598-023-47570-2 article EN cc-by Scientific Reports 2023-11-22

Objective: Due to the weak ascending aorta, it is extremely challenging establish an anterograde selective cerebral perfusion (ASCP) model in rabbits, especially when cardioplegic arrest required. Herein, aim of this study was a rabbit ASCP with cardiac being easily performed and similar clinical scenario. Materials methods: Twenty-two adult New Zealand white rabbits were selected for establishment another 22 utilized blood donation. The cardiopulmonary bypass (CPB) circuit consisted roller...

10.1177/0267659115599835 article EN Perfusion 2015-08-11

This study aimed to assess the impact of COVID-19 pandemic on allergy indicators in adult patients. We analyzed 8015 tIgE and 34,163 allergen detection results from 2018 2023. Patients were categorized into pre-pandemic (2018-2019), pandemic-period (2020-2022), post-pandemic (2023) groups. Group comparisons logistic regression analyses examined relationship between relevant factors positivity rates. Inverse probability treatment weighting (IPTW) using propensity scores was applied address...

10.22541/au.172454763.38390303/v1 preprint EN Authorea (Authorea) 2024-08-25

<title>Abstract</title> This study aimed to assess the impact of COVID-19 pandemic on allergy indicators in adult patients. We analyzed 8015 tIgE and 34,163 allergen detection results from 2018 2023. Patients were categorized into pre-pandemic (2018–2019), pandemic-period (2020–2022), post-pandemic (2023) groups. Group comparisons logistic regression analyses examined relationship between relevant factors positivity rates. Inverse probability treatment weighting (IPTW) using propensity...

10.21203/rs.3.rs-4782843/v1 preprint EN cc-by Research Square (Research Square) 2024-09-03

Beckebaum, S; Yu, Z; Lindemann, M; Klein, C G.; Sotiropoulos, G; Radtke, A; Gerken, Cicinnati, V R. Author Information

10.1097/01.tp.0000331549.03857.a6 article EN Transplantation 2008-07-27

Objective: To evaluate the perioperative period and long-term effects of minimally invasive gasless laparoscopic transhiatal esophagectomy (LTE) combined thoracoscopic (CTLE) for stageⅠ-Ⅲ cervical esophageal cancer. Methods: The clinical data 158 consecutive patients with cancer stageⅠto Ⅲ who underwent CTLE or LTE in Department Thoracic Surgery, Beijing Tongren Hospital from January 2008 to December 2019 were retrospectively analyzed. A total 40 pairs cases matched (40 surgery) after using...

10.3760/cma.j.cn112137-20210521-01177 article EN PubMed 2022-02-08

A new round of power system reform is in full swing China, but there still controversy over which electricity market clearing rules to adopt. Firstly, this paper introduces the background current and review research progress experimental economics rules. Then, it analyzes two market, namely, uniform spread aggregation clearing. Finally, an simulation experiment designed based on supply demand situation China compare terms price, equilibrium welfare members. The results show midpoint model...

10.1109/cseps53726.2021.00059 article EN 2021-05-01
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