A5101739566- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Drug-Induced Hepatotoxicity and Protection
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Liver physiology and pathology
- Cancer-related molecular mechanisms research
- Advancements in Semiconductor Devices and Circuit Design
- Urological Disorders and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Alcohol Consumption and Health Effects
- RNA modifications and cancer
- Renal and related cancers
- MicroRNA in disease regulation
- Urinary Bladder and Prostate Research
- Ferroptosis and cancer prognosis
- Pelvic floor disorders treatments
- Semiconductor materials and devices
- Clinical Nutrition and Gastroenterology
- Hepatitis Viruses Studies and Epidemiology
- Mesenchymal stem cell research
- Liver Diseases and Immunity
- Cancer Mechanisms and Therapy
- Facial Nerve Paralysis Treatment and Research
Chinese PLA General Hospital
2019-2025
Jiangnan University
2025
Central South University
2025
Guangzhou Medical University
2016-2024
Shandong University of Technology
2024
Shandong Provincial Hospital
2013-2024
Shandong First Medical University
2019-2024
Guangzhou Women and Children Medical Center
2014-2024
Zhejiang Chinese Medical University
2023-2024
302 Military Hospital of China
2013-2023
Mesenchymal stem cell (MSC) infusion was reported to improve liver function in patients with decompensated cirrhosis (DLC); however, whether the medication can outcome of these is poorly understood.
•This is the first prospective validation of Baveno VII recompensation definition in patients with HBV-related cirrhosis.•A stable improvement liver function tests was defined as MELD <10 and/or ALB & INR TBIL within Child-Pugh A.•On-treatment scores may be more predictive probability than baseline scores.•Prompt antiviral therapy effective for cirrhosis, even under severe conditions. Background AimsAntiviral improves clinical outcomes chronic hepatitis B (CHB), including those cirrhosis. In...
The continuously increasing mass activity in formic acid oxidation reaction (FAOR) is the key to achieving practical application of direct fuel cells (DFAFCs). Herein, Rh‐based dual‐metal atomic pairs supported on nitrogen‐doped carbon catalysts [DAP‐(M, Rh)/CN] with adjacent interatomic Rh‐M (M = V, Cr, Mn, Fe, Co, Ni, Cu) have been synthesized by a “host‐guest” strategy. We discovered that DAP‐(Cr, Rh)/CN shows highest 64.1 A·mg‐1, which 3.8 times higher than single atom Rh catalyst (17.0...
MicroRNAs (miRNAs) are widely recognized as key players in cancer progression and drug resistance, but less is known about the role of miRNAs triple-negative (estrogen receptor, progesterone HER-2/neu) breast (TNBC). The aim present study was to examine expression profile explore their possible roles TNBC. Differentially expressed were identified by miRNA microarray verified quantitative real-time polymerase chain reaction. miR-93 assessed situ hybridization 119 cases cancer. Cell...
OBJECTIVES: Acute insults from viruses, infections, or alcohol are established causes of decompensation leading to acute-on-chronic liver failure (ACLF). Information regarding drugs as triggers ACLF is lacking. We examined data producing and analyzed clinical features, laboratory characteristics, outcome, predictors mortality in patients with drug-induced ACLF. METHODS: identified precipitants among prospective cohort the Asian Pacific Association Study Liver (APASL) Research Consortium...
Autoimmune hepatitis (AIH) is considered less common in the Asia Pacific region. Due to this, AIH flare as a cause of acute on chronic liver failure (ACLF) often overlooked and treatment delayed. We aimed at defining clinical histopathological spectrum role steroid therapy AIH-ACLF. Patients with AIH-ACLF, prospectively recruited followed between 2012 2017, were analyzed from Asian Association for Study Liver ACLF Research Consortium (AARC) data base. Diagnosis was confirmed using...
Abstract Background and Aim Plasma‐exchange (PE) has improved survival in acute liver failure by ameliorating systemic inflammatory response syndrome (SIRS). We evaluated PE compared it to Fractional Plasma Separation Adsorption (FPSA) standard medical treatment (SMT) a large multinational cohort of ACLF patients. Methods Data were prospectively collected from the AARC database analysed. Matching propensity risk score (PRS) was performed. Competing analysis done identify deaths because...
Hepatic recompensation may be achieved in patients with decompensated cirrhosis due to chronic hepatitis B (CHB) upon effective suppression of viral replication by nucleos(t)ide analogues (NAs). However, the optimal timing and predictors subsequent clinical course CHB
Abstract Natural killer (NK) cells can induce liver fibrosis remission by killing hepatic stellate (HSCs) and producing interferon (IFN)-γ in a mouse model; however, their anti-fibrotic immune-characteristics regulatory mechanisms HSCs remain to be determined, especially livers from HBV-infected cirrhosis (LC) patients. We analyzed frequency, phenotype function of peripheral NK subsets 43 HBV-LC found that LC patients displayed decreased activation status activity compared with those chronic...
The offspring of super-multiparous sows face problems such as decreased growth performance, poor meat quality and even diseases in animal husbandry. Gama-aminobutyric acid (GABA) has long been known to promote suppress inflammation, but little is about the mechanisms. A total 72 growing-finishing pigs from 8th generation were randomly allotted 2 groups with 6 replicates per treatment receive a corn-soybean basal diet or supplemented 20 mg/kg GABA for 60 d. After animal-trial period, samples...
To construct an integrated nomogram combining protein induced by vitamin K antagonist-II (PIVKA-II), alpha fetoprotein (AFP) and other clinical factors to detect microvascular invasion (MVI) in early hepatocellular carcinoma (HCC) patients with single nodule.One hundred eleven HCC were enrolled the present study 43 diagnosed MVI. Serum levels of PIVKA-II, AFP laboratory indicators detected. Chi-squared test, t-test logistic regression employed statistic analysis. A independent predictors was...
Background Acute-on-chronic liver failure (ACLF) represents the terminal and most lethal phase of acute decompensated cirrhosis. Systemic inflammation plays a critical role in pathogenesis ACLF. reaction syndrome (SIRS) is marker ongoing inflammation. Therefore, we aim to evaluate relationship sterile SIRS with hepatitis B virus (HBV)-related ACLF (HBV-ACLF). Methods HBV-ACLF patients who were hospitalized between December 2016 2018 retrospectively analyzed. All followed up until 90 days....