Chea Yeon Lee

ORCID: 0000-0003-1469-0025
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About
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Research Areas
  • Phytochemicals and Medicinal Plants
  • Viral Infectious Diseases and Gene Expression in Insects
  • Medicinal Plants and Neuroprotection
  • Cancer, Hypoxia, and Metabolism
  • Bioactive Compounds and Antitumor Agents
  • PI3K/AKT/mTOR signaling in cancer
  • Metabolism, Diabetes, and Cancer

Kangwon National University Hospital
2021

Scripps Korea Antibody Institute
2020

The Warburg effect is important for cancer cell proliferation. This phenomenon can be flexible by interaction between glycolysis and mitochondrial oxidation energy production. We aimed to investigate the anticancer effects of pyruvate dehydrogenase kinase inhibitor, dichloroacetate (DCA) respiratory complex I inhibitor metformin in liver cells. DCA and/or on HepG2, PLC/PRF5 human lines, MH-134 murine hepatoma primary normal hepatocytes using MTT assay. Inhibition lactate/ATP production...

10.3390/ijms221810027 article EN International Journal of Molecular Sciences 2021-09-17
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