A5060359501- Cytomegalovirus and herpesvirus research
- Systemic Lupus Erythematosus Research
- Herpesvirus Infections and Treatments
- Immune Cell Function and Interaction
- Viral gastroenteritis research and epidemiology
- Animal Disease Management and Epidemiology
- T-cell and B-cell Immunology
- Viral Infections and Immunology Research
- Respiratory viral infections research
- Open Education and E-Learning
- Viral Infections and Vectors
- Bat Biology and Ecology Studies
- Teaching and Learning Programming
- Influenza Virus Research Studies
- Cryospheric studies and observations
- Experimental Learning in Engineering
- COVID-19 Impact on Reproduction
- Motivation and Self-Concept in Sports
- Immune Response and Inflammation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Traumatic Brain Injury Research
University of Arizona
2023-2024
Louisiana State University
2020-2023
Bluffton University
2018
Villanova University
2006
ABSTRACT In the United States (US), biosafety and biosecurity oversight of research on viruses is being reappraised. Safety in virology paramount frameworks should be reviewed periodically. Changes made with care, however, to avoid impeding science that essential for rapidly reducing responding pandemic threats as well addressing more common challenges caused by infectious diseases. Decades uniquely positioned US able respond COVID-19 crisis astounding speed, delivering life-saving vaccines...
Human cytomegalovirus (HCMV) is a ubiquitous pathogen that infects the majority of world population and causes lifelong latent infection. HCMV has been shown to exacerbate cardiovascular diseases, including myocarditis, vascular sclerosis, transplant vasculopathy. Recently, we have murine CMV (MCMV) recapitulates dysfunction observed in patients with HCMV-induced myocarditis. To understand viral mechanisms involved CMV-induced heart dysfunction, further characterized cardiac function...
Visualization and interactivity are valuable active learning techniques that can improve mastery of difficult concepts. In this paper we describe jFAST, an easy-to-use graphical software tool for teachers students, with emphasis on introductory level finite state machine topics. The jFAST enables visual design, exploration simulation a variety machines, primary goal enhancing teaching effectiveness in subject, particularly less advanced computer science students. architecture functionality...
Human cytomegalovirus (HCMV) is associated with increased risk of chronic diseases the heart and vasculature, including myocarditis, atherosclerosis, transplant vasculopathy. To investigate CMV infection heart, murine (MCMV) was used to evaluate both acute latent subsequent phenotypic functional consequences infection. Female BALB/c mice were intraperitoneally (i.p.) inoculated 1 × 106 pfu MCMV evaluated at 14 50 days postinfection (dpi). At each time point, echocardiography cardiac function...
Myotis septentrionalis (Northern Long-eared Bat) is widely distributed in North America, from the Appalachians to Maritime Provinces and west British Columbia. In November 2016, we captured 2 non-reproductive Northern Bats, 1 female male, nets set Beaufort County, coastal South Carolina. Previous records for species indicate its nearest breeding colonies are >350 km away, it had not been documented Carolina outside Blue Ridge region. Although Bat known move between summer roosts winter...
Human cytomegalovirus (HCMV) is a global health threat due to its ubiquity and lifelong persistence in infected people. During latency, host CD8+ T cell responses HCMV continue increase phenomenon known as memory inflation. We used murine CMV (MCMV) model for characterize the inflation response wild-type MCMV (KP) latency-defective mutant (ΔM33stop), which lacks M33, an chemokine receptor homolog. M33 essential normal reactivation from latency this was leveraged determine whether vivo...
Visualization and interactivity are valuable active learning techniques that can improve mastery of difficult concepts. In this paper we describe jFAST, an easy-to-use graphical software tool for teachers students, with emphasis on introductory level finite state machine topics. The jFAST enables visual design, exploration simulation a variety machines, primary goal enhancing teaching effectiveness in subject, particularly less advanced computer science students. architecture functionality...
Human cytomegalovirus (HCMV) is a widespread pathogen that causes lifelong latent infection in the majority of world population. HCMV associated with increased incidence and severity many cardiovascular diseases including myocarditis, atherosclerosis, transplant vasculopathy. Due to species-restricted nature infection, murine (MCMV) useful model recapitulates features system. While vivo MCMV studies are able answer questions regarding pathogenesis vitro experiments using cell lines tools...
The salivary glands are a crucial site of replication for human cytomegalovirus (HCMV) and its murine counterpart, (MCMV). Studies MCMV often involve the use BALB/c strain mice, but most in vitro assays carried out NIH 3T3 cell line, which is derived from Swiss Albino mice. This report describes BALB/c-derived mouse gland line immortalized using SV40 large T antigen. Cells stained positive PDGFR1 negative E-cadherin PECAM-1, indicating mesenchymal origin. has been named (mSGM), shows promise...
Abstract The salivary glands are a crucial site of replication for human cytomegalovirus (HCMV) and its murine counterpart, (MCMV). Studies MCMV often involve the use BALB/c strain mice, but most in vitro assays carried out NIH 3T3 cell line, which is derived from Swiss Albino mice. This report describes BALB/c-derived mouse gland line immortalized using SV40 large T antigen. Cells stained positive PDGFR1 negative E-cadherin PECAM-1, indicating mesenchymal origin. has been named (mSGM),...