A5063378973- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- RNA modifications and cancer
- Circular RNAs in diseases
- RNA Research and Splicing
- Oral and Maxillofacial Pathology
- Essential Oils and Antimicrobial Activity
- Cancer Mechanisms and Therapy
- Phytochemistry and Biological Activities
- Flavonoids in Medical Research
- Cancer, Hypoxia, and Metabolism
- Cell death mechanisms and regulation
- Trace Elements in Health
- Synthesis and biological activity
- Biological Activity of Diterpenoids and Biflavonoids
- Glaucoma and retinal disorders
- Bioactive Compounds and Antitumor Agents
- Traditional Chinese Medicine Analysis
- Cytokine Signaling Pathways and Interactions
- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Mechanisms of cancer metastasis
- Natural product bioactivities and synthesis
- Ion Channels and Receptors
- Bone Tumor Diagnosis and Treatments
Adıyaman University
2016-2025
Gaziantep University
2013-2022
University of La Guajira
2022
University of Mosul
2022
Planta
2022
Abstract In this study, antioxidant, oxidant, antimicrobial, and antiproliferative activities of Asparagus acutifolius L. officinalis L., known for their nutritional properties, were determined. context, methanol (MeOH) dichloromethane (DCM) extracts plants obtained. Total antioxidant status (TAS), total oxidant (TOS), oxidative stress index (OSI) determined using Rel Assay kits. Antimicrobial plant against the test microorganisms agar dilution method. Antiproliferative activity was tested...
The potential toxic effects of several pesticides, including imidacloprid on non-target organisms have not been clearly established. Also, the chronic non-toxic doses cognitive function in mammals are unknown. In this study, different learning and memory infant adult rats were evaluated, expressions genes synthesizing proteins known to be associated with brain tissues also documented. 0.5, 2 8 mg/kg administered newborn Wistar albino by gavage. Their activities expression levels inotropic...
Colorectal cancer (CRC) is the most common of gastrointestinal tract. Different factors are responsible for development CRC. Transient Receptor Potential (TRP) which an important component calcium channel associated with several pathological conditions like cancer, neurodegenerative and cardiovascular diseases. Thirty members family TRP ion in mammals have been determined till now. The aim this study to investigate TRPM, TRPV TRPC gene expression levels tumor tissues CRC patients analyze...
Deregulated microRNA (miRNA) expression has been shown to be involved in the pathogenesis of several types cancers including colorectal cancer (CRC). Thus, determining miRNA targets genes that play critical role malignant transformation is very important. Here, levels tumor suppressor microtubule-associated 1 (MTUS1) and its regulatory miRNAs were reported. Predicted validated MTUS1 gene was determined by a computational approach. Expressions using 96.96 Dynamic Array™ integrated fluidic...
Kisspeptin–1 (KISS–1) and Spexin (SPX) are neuropeptides that play crucial roles in metabolism sexual function, with their expression levels tissues potentially influenced by antioxidant treatments. This study aimed to investigate the effects of cortexin treatment against ischemia–reperfusion injury (I/R) resulting from testicular torsion on KISS–1 SPX tissues. Twenty–eight male Sprague–Dawley, rats, aged 8–10 weeks, were divided into four equal groups: control, torsion, torsion/ detorsion,...
In this comprehensive study, we aimed to investigate pharmacological properties and therapeutic significance of saffron in osteosarcoma cancer cells.Plant materials were obtained from Safranbolu district Karabuk, Turkey. For the determination anticancer properties, thiazolyl blue tetrazolium bromide (MTT) cell viability, colony formation, wound closure, DNA ladder assays gene expression analysis by real-time PCR performed. Also, cellular inflammation, total antioxidant oxidants status...
Breast cancer is the most common malignancy predominantly affecting women. To date, numerous numbers of studies were reported novel genetic contributors with diagnostic, prognostic, and therapeutic potential for breast carcinogenesis. However, role urotensin-II in carcinogenesis has not been elucidated yet. Urotensin-II a somatostatin-like cyclic tiny peptide identified by its potent vasoconstrictor activity. Soon after discovery, involvement many disease states as well expression various...
Chemical constituents and cytotoxic effect from the barks of Goniothalamus chinensis Merr. & Chun. growing in VietnamLoi Vu Duc, Tung Bui Thanh, Hai Nguyen Vung Tien
Uridine 5′-diphospho-glucuronosyltransferases (UGT) are the key players in biotransformation of drugs, xenobiotics, and endogenous compounds. Particularly, UDP-glucuronosyltransferase 1A (UGT1A) participates a wide range biological pharmacological processes plays critical role conjugation exogenous components. Thirteen alternative splicing products were produced from UGT1A gene locus designated as UGT1A1 UGT1A3–10. A growing amount evidence suggests that they have important roles...
Long non-coding RNAs (lncRNAs) are found to play crucial roles in several biological processes and have been associated with many complex human diseases including cancers. Several lines of evidences indicate that lncRNAs deregulated cancer tissues. In this particular study, differential expression long intergenic RNA 663 (LINC00663) was demonstrated various cell healthy tissues by using RT-PCR qPCR methods. While level LINC00663 most prominent thyroid gland uterus, it is least expressed...
Schiff bases (imines or azomethines) are versatile ligands synthesized from the condensation of amino compounds with active carbonyl groups and used for many pharmaceutical medicinal applications. In our study, we aimed to determine cytotoxic, antifungal larvicidal activities biologically potent bis-sulfonamide base derivatives that were re-synthesized by us. For this aim, 16 tested their properties. Among series, A1B2, A1B4, A4B2, A4B3, A4B4 shown have cytotoxic activity against cancer lung...