- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Pelvic floor disorders treatments
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Kidney Stones and Urolithiasis Treatments
- Hormonal and reproductive studies
- Urologic and reproductive health conditions
- Ureteral procedures and complications
- Pediatric Urology and Nephrology Studies
- Adipose Tissue and Metabolism
- Anesthesia and Pain Management
- Renal cell carcinoma treatment
- Renal and related cancers
- Foreign Body Medical Cases
- Hormonal Regulation and Hypertension
- Protease and Inhibitor Mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Urinary and Genital Oncology Studies
- Streptococcal Infections and Treatments
- Pluripotent Stem Cells Research
- Glutathione Transferases and Polymorphisms
- Cardiovascular Syncope and Autonomic Disorders
- Connexins and lens biology
Istituto Nazionale di Riposo e Cura per Anziani
2015-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2024
Marche Polytechnic University
2004-2009
Ospedali Riuniti Umberto I
2003-2009
Azienda Ospedaliero Universitaria Ospedali Riuniti
2005-2009
We evaluated the efficacy of alpha1-adrenergic antagonist tamsulosin for conservative expulsive therapy in patients with ureteral colic due to juxtavesical stones.A total 60 consecutive symptomatic stones located tract ureter were randomly divided into group 1--30 who received oral floroglucine-trimetossibenzene 3 times daily and 2--30 0.4 mg daily. The 2 groups 30 deflazacort 10 days plus cotrimoxazole 8 75 diclofenac injected intramuscularly on demand. Ultrasound followup medical visits...
Recent studies show the interesting efficacy of different drug combinations for spontaneous expulsion distal ureteral stones. We performed a randomized, prospective study to assess and compare 3 drugs as medical expulsive therapy calculi.A total 210 symptomatic patients with calculi greater than 4 mm were randomly allocated home treatment phloroglucinol, tamsulosin or nifedipine (groups 1 3, respectively). Each group was given corticosteroid antibiotic prophylaxis an injectable nonsteroidal...
Abstract Aim Several studies have proposed a role for α 1 adrenoceptors (ARs) in ureteral physiology, indicating that they are present the ureter; however, few been done to identify AR subtypes this area. Thus, study was carried out characterize subtype gene and protein expression proximal, medial, distal region of human ureter. Methods Molecular characterization were analyzed by semi‐quantitative RT‐PCR. studied saturation binding curves competition with selective antagonists. Analysis data...
General anesthesia is associated with high morbidity/mortality in comorbid older adults. Thoracic continuous spinal anesthesia/analgesia (TCSA) may be an alternative for major abdominal surgery. We report a one-year experience of the use TCSA Italian geriatric center.Retrospective review case notes high-risk patients (ASA class ≥III) who underwent surgery between May 2017-May 2018. was performed 21-gauge Tuohy-shaped needle and 24-gauge catheter (level insertion T6-7 T10-11). Hyperbaric...
We aim to evaluate the incidence of incontinence following laser endoscopic enucleation prostate (EEP) comparing en-bloc (Group 1) versus 2-lobe/3-lobe techniques 2). performed a retrospective review patients undergoing EEP for benign prostatic enlargement in 12 centers between January 2020 and 2022. Data were presented as median interquartile range (IQR). Univariable multivariable logistic regression analysis was factors associated with stress urinary (SUI) mixed (MUI). There 1711 Group 1...
Abstract Purpose To evaluate complications and urinary incontinence (UI) after endoscopic enucleation of the prostate (EEP) stratified by volume (PV). Methods We retrospectively reviewed patients with benign prostatic hyperplasia who underwent EEP different energy sources in 14 centers (January 2019–January 2023). Inclusion criteria: ≥ 80 ml. Exclusion cancer, previous prostate/urethral surgery, pelvic radiotherapy. Primary outcome: complication rate. Secondary outcomes: incidence factors...
We investigated the safety and efficacy of transurethral resection prostate (TURP) for glands between 70 150 ml.We prospectively evaluated 113 patients treated with TURP benign prostatic hyperplasia. A total 57 a volume less than ml were assigned to group 1, while 56 2. Preoperative parameters considered in each patient volume, International Prostate Symptom Score (I-PSS), urinary flow rate measurement (Qmax) post-void residual urine (PVR). Operative time, resected tissue weight all...
Radical cystectomy (RC) is the gold standard therapy in nonmetastatic muscle-invasive bladder cancer and usually performed under general anesthesia (GA). GA high risk most older patients due to comorbidities. Continuous spinal (CSA) may be an alternative solution reduce postoperative morbidity elderly. The aim of this study was assess feasibility, morbidity, mortality RC CSA octogenarian patients.
We investigated ultrasound alterations of the preprostatic sphincter in patients with chronic prostatitis-chronic pelvic pain syndrome. evaluated frequency these alterations, standardized their measurement and correlated them symptoms syndrome.In 37 syndrome 23 healthy volunteers certain parameters were measured by transrectal ultrasound, including prostate volume, hypoechoic periurethral zone posterior lip thickness, bladder neck detrusor thickness degree echogenicity anterior fibromuscular...
Fournier’s gangrene (FG) is a disease involving necrosis of perineum and external genitalia; in 95% cases it possible to diagnose the just by physical examination. The clinical presentation FG varies from an initial localized infection large areas with necrotizing infection. typically affect elderly men (6°-7° decade) important systemic comorbidities; women are less frequently affected. Despite improvements diagnosis management, mortality rate nowadays between 20% 43%. severity dependent...
Bleeding is the most common complication of transurethral resection prostate and simple open prostatectomy, especially in men on antiplatelet/anticoagulant therapy. The present study aimed to evaluate safety effectiveness thulium laser vapoenucleation (ThuVEP) for benign prostatic hyperplasia patients chronic antithrombotic medications. Between January 2015 December 2019, 88 underwent procedure under agents our center. mean age was 74.7 ± 6.1 years. Median volume 66.5 mL. Patients oral...
Objectives To assess if the lockdown period (March–April 2020) during coronavirus disease‐19 outbreak in Italy influenced number, presentation, and treatment of urgent admissions to emergency department for ureteral lithiasis, evaluate same variables reopening phase (May–June 2020). Methods We performed a retrospective analysis patients admitted three different hospitals (two hubs). Demographics data on acute pyelonephritis, kidney injury, urinoma, hematuria, inpatient admission/discharge...
Prostate cancer cell motility and invasion have been linked to the up-regulated signaling of epidermal growth factor receptor urokinase-type plasminogen activator receptor. We analyzed expression serum in patients with clinical suspicion prostate evaluate possible role as markers.Serum was collected from 79 consecutive referred our institution for transrectal ultrasound guided biopsy. All blood samples were obtained before Total antigen measured by specific enzyme-linked immunosorbent...