A5031824438- Aluminum Alloys Composites Properties
- Rheumatoid Arthritis Research and Therapies
- Metallurgy and Material Forming
- Autoimmune and Inflammatory Disorders Research
- Chronic Lymphocytic Leukemia Research
- Spondyloarthritis Studies and Treatments
- Powder Metallurgy Techniques and Materials
- Pharmacological Effects of Natural Compounds
- Cytokine Signaling Pathways and Interactions
- Mechanical Behavior of Composites
- Medical Research and Treatments
- Psoriasis: Treatment and Pathogenesis
- Bone and Joint Diseases
- Systemic Lupus Erythematosus Research
- Elasticity and Material Modeling
- 3D Printing in Biomedical Research
- Gout, Hyperuricemia, Uric Acid
- Adipokines, Inflammation, and Metabolic Diseases
- Autophagy in Disease and Therapy
- Ocular Surface and Contact Lens
- Composite Material Mechanics
- Renal Diseases and Glomerulopathies
- Injury Epidemiology and Prevention
- Cellular Mechanics and Interactions
- Diabetic Foot Ulcer Assessment and Management
Tianjin Medical University
2019-2024
Guangdong Polytechnic Normal University
2023-2024
Tianjin First Center Hospital
2019-2024
Osteoarthritis (OA) is a common joint degenerative disease. Vitamin D (VD) essential for bone health. We hypothesized that active VD could be used as therapeutic treatment OA. Low serum levels of 25-hydroxyvitamin [25(OH)D] have been found in patients with OA, and thus the level diagnostic To test this, we established mouse model The results from staining hematoxylin–eosin Safranin O – Fast Green indicated reduced symptoms OA mice. Western blotting increased activity p-AMPK–AMPK signaling...
Cell printing is a promising technology in tissue engineering, with which the complex three-dimensional constructs can be formed by sequentially cells layer layer. Though some cell experiments commercial inkjet printers show possibility of this idea, there are problems, such as damage due mechanical impact during direct writing, include two processes ejection and landing. observed bioprinting process often simply attributed to interactions between substrate. However, reality, also arise from...
To determine the distribution and diagnostic value of peripheral enthesitis detected by whole-body MRI (WBMRI) in axial spondyloarthritis (axSpA) diagnosis, to score axSpA assessment.Sixty patients [mean age 33.2 (24.8-40.6) years] 50 controls with chronic low back pain (LBP) 34.7 (28.3-41.1) were enrolled. The gold standard was physician's comprehensive diagnosis based on current classification criteria physical examination. All subjects underwent WBMRI, 47 entheses assessed for each...
Background Few studies have focused on the ability of progranulin to predict postoperative disease activity in rheumatoid arthritis (RA) patients who undergone surgery. This study evaluated serum levels active RA and analyzed its relationship with activity. Methods One hundred thirty-two 72 healthy subjects were included this study. Serum was measured, clinical data collected. The 1-year Disease Activity Score 28 joints calculated C-reactive protein (DAS28-CRP) scores as an indicator...
The present paper introduces an innovative strain energy function (SEF) for incompressible anisotropic fiber-reinforced materials. This SEF is specifically designed to understand the mechanical behavior of carbon fiber-woven fabric. considered model combines polyconvex invariants forming integrity basisin polynomial form, which inspired by application Noether's theorem. A single solution can be obtained during identification because relationship between we have constructed and material...
The purpose of this hospital clinic based study was to evaluate the potential risk factors associated with prevalence MetS in RA population.From January 2015 October 2018, 717 patients and healthy controls who were treated or performed physical examination Tianjin First Central Hospital enrolled study. basic disease diagnoses recorded. A questionnaire on all participants assess demographic details cohort. Moreover, laboratory indicators related glucose lipid metabolism also detected. for...
Our study intends to assess whether resveratrol can ameliorate osteoporosis in mice. Ovariectomized (OVX) mice were established measure SFRP1 level and SFRP1-siRNA was used its effect on BMSCs osteogenesis. significantly up-regulated bone tissues of OVX with a gradual decrease during However, it not changed differentiation towards osteoclasts. knockdown increased mineralization potentiality, elevated ALP activity upregulated several osteoblast-specific genes. Moreover, loss reduced...
Rheumatoid arthritis (RA), which normally manifests as a multi‑joint inflammatory reaction, is common immunological disease in clinical practice. However, the pathogenesis of RA has not yet been fully elucidated. Rituximab (RTX) an effective drug treatment RA, however its therapeutic efficacy and mechanism action require further investigation. Thus, present study aimed to screen candidate key regulatory genes explain potential mechanisms RA. Gene chips normal joint tissues were analyzed and,...
Background. Fungal infection in the lungs can cause fungal infectious diseases. This disease develops rapidly and involves a wide range. Pathogenic fungi are also more serious types of pathogenic bacteria. If it invades deep organs tissues, will endanger life, so needs timely diagnosis. Aim. To investigate diagnostic value serum soluble myeloid cell triggering receptor-1 (sTREM-1), procalcitonin (PCT), 1,3-β-D glucan detection immune related lung complicated with infection. Methods. In this...
Objective To explore the difference between prevalence of metabolic syndrome (MetS) and its influencing factors rheumatoid arthritis (RA) patients osteoarthritis (OA) patients. Methods 2 024 with RA were selected as experimental group inthe First Central Hospital Tianjin from January 1, 2014 to March 12, 2019. A total 1 271 OA who treated at same time served control group.Relevant indicators measured, correlation analysis was performed using logistic regression. Results The MetS...