A5077448390- Antibiotics Pharmacokinetics and Efficacy
- Drug Transport and Resistance Mechanisms
- Diabetes Treatment and Management
- Neutropenia and Cancer Infections
- Antifungal resistance and susceptibility
- Economic and Financial Impacts of Cancer
- Plant-based Medicinal Research
- Pneumonia and Respiratory Infections
- Lung Cancer Treatments and Mutations
- Pharmacy and Medical Practices
- Pneumocystis jirovecii pneumonia detection and treatment
- Peptidase Inhibition and Analysis
- Eosinophilic Disorders and Syndromes
- Pharmacogenetics and Drug Metabolism
- Hematopoietic Stem Cell Transplantation
- Esophageal Cancer Research and Treatment
- Chronic Myeloid Leukemia Treatments
- Antibiotic Resistance in Bacteria
- Pesticide Residue Analysis and Safety
- Gastric Cancer Management and Outcomes
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Chronic Lymphocytic Leukemia Research
- Drug-Induced Adverse Reactions
- Lung Cancer Diagnosis and Treatment
Fujian Medical University
2017-2025
Union Hospital
2017-2025
Therapeutics Clinical Research
2019
Ibero American University
2019
Objective: To evaluate the pharmacoeconomic benefits of four Glucagon-like peptide-1 receptor agonists (GLP-1RA) and lifestyle management for treatment obesity from perspective Chinese healthcare system.
This study aimed to describe the population pharmacokinetics (PopPK) of ceftazidime-avibactam (CAZ-AVI) in adult patients, and develop optimal dosing regimens for both non-critically ill critically patients by combining different pharmacokinetic/pharmacodynamic (PK/PD) targets. A prospective, single-center involving who were infected with CRKP received CAZ-AVI therapy was conducted. Nonlinear mixed-effect modeling used a PopPK model. The regimen assessed using Monte Carlo simulation....
Purpose Dipeptidylpeptidase-4 (DPP-4) inhibitors, including linagliptin, alogliptin, saxagliptin, sitagliptin, and vildagliptin, are used for the treatment of type 2 diabetes mellitus (T2DM) patients in China. This study assessed economic outcomes different DPP-4 inhibitors with T2DM inadequately controlled metformin Chinese context. Materials Methods In this study, validated Outcomes Model (COMT) was conducted to project from perspective healthcare service providers. Efficacy safety,...
Purpose: The aim of this study is to assess the bioequivalence a new generic formulation and branded levocetirizine dihydrochloride in healthy Chinese volunteers under fasting fed conditions, food-intake effect on pharmacokinetic properties also evaluated. Patients methods: Volunteers were randomly allocated into two groups receive single oral dose or respectively. Blood samples collected at designated time points. Plasma concentrations determined by UFLC-MS/MS. Safety evaluations carried...
Background: Urothelial carcinoma is a significant health concern in the United States (US), with high mortality and economic burdens. The CheckMate-901 trial showed promising survival benefits for nivolumab combined gemcitabine cisplatin followed by maintenance therapy (nivolumab-combination) as first-line treatment of unresectable or metastatic urothelial (UC), but its cost-effectiveness unclear. Objectives: This study aimed to evaluate nivolumab-combination versus standard chemotherapy...
Abstract Purpose This study aimed to investigate the interactions between posaconazole (POS) and intravenously/orally administered Cyclosporine A (CsA) in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Methods We included 118 HSCT patients who received CsA POS simultaneously January 2017 June 2020 this study. The ratio of blood concentration (ng/mL) dosage (mg/day) (C/D) before after initiation was compared. Results After POS, level increased 1 2 times 66% (78/118) compared...