- Psychopathy, Forensic Psychiatry, Sexual Offending
- Sexuality, Behavior, and Technology
- Gut microbiota and health
- Probiotics and Fermented Foods
- Glycosylation and Glycoproteins Research
- Sexual function and dysfunction studies
- Parasite Biology and Host Interactions
- Helminth infection and control
- Sexual Assault and Victimization Studies
- Criminal Justice and Corrections Analysis
- Digestive system and related health
- Child Abuse and Trauma
- Stalking, Cyberstalking, and Harassment
- Psychological and Temporal Perspectives Research
- Crime Patterns and Interventions
- Psychological Well-being and Life Satisfaction
- Parasites and Host Interactions
- Cardiac Arrhythmias and Treatments
- Intimate Partner and Family Violence
- Infant Nutrition and Health
- Cardiac electrophysiology and arrhythmias
- Adolescent Sexual and Reproductive Health
- Sport Psychology and Performance
- Personality Disorders and Psychopathology
- Mental Health and Psychiatry
Royal Ottawa Mental Health Centre
2013-2023
University of Calgary
2020-2023
Beaumont Hospital
2020-2021
Trinity College Dublin
2013-2021
University College Cork
1999-2020
Purdue University West Lafayette
2020
University of Ottawa
2008-2020
University of Glasgow
2006-2019
Flinders University
2019
Royal Darwin Hospital
2019
Background: The enteric bacterial flora has been implicated in the pathogenesis of enterocolitis and colon cancer C57BL/6 IL‐10 knockout mice. Probiotic Lactobacilli modify are thought to have a beneficial effect on enterocolitis. We conducted controlled feeding trial mice using probiotic Lactobacillus salivarius ssp. s alivarius UCC118. Aim: To determine consumption gastrointestinal microflora, tumour development colitis Methods: Twenty were studied (10 consumed organisms milk 10 unmodified...
The alpha-D-galactopyranosyl-binding lectin previously purified from Bandeiraea simplicifolia seeds (Hayes, C.H., and Goldstein, I.J. (1974) J. Biol. Chem. 249, 1904) is shown to consist of five isolectins separable on polyacrylamide gel electrophoresis at pH 9.5. are tetrameric structures composed various combinations two different glycoprotein subunits designated A B. B appear be immunochemically indistinguishable against rabbit antisera prepared the isolectin mixture. subunit contains no...
Potential safety concerns relative to impaired cognitive function may exist when high folic acid exposures are combined with low vitamin B-12 status. We aimed examine the relation of coexistence folate and status function, utilizing various definitions "high" Cross-sectional data from older adults (≥60 y; n = 2420) 2011–2014 NHANES were analyzed. High was defined as unmetabolized serum (UMFA) > 1 nmol/L or total 74.1 nmol/L, methylmalonic 271 < 150 pmol/L. Logistic regression models...
Objective: To evaluate the long-term psychological impact of Hurricane Sandy on New York residents.Design: Prospective, cross-sectional study.Setting: Community-based study.Participants: From October 2013 to February 2015, 669 adults in Long Island, Queens, and Staten Island completed a survey their behavioral health, demographics, hurricane (ie, exposure).Main outcome measures: Depression, anxiety, post-traumatic stress disorder (PTSD).Results: Using multivariable logistic regression...
Association constants for the binding of methyl a -~galactopyranoside (methyl a-D-Galp) and 2-acetamido-2-deoxy-a-~-galactopyranoside a-D-GalNAcp) to three Bandeiraea simplicifolia isolectins (&, AZB2, B4) were determined by equilibrium dialysis fluorescence enhancement measurements.The A B subunits appear have approximately same KaesOc a-D-Galp: 1.45 X lo4, 1.98 2.06 lo4 M" &, A2B2, B4, respectively, as dialysis.Fluorescence measurements on B4 gave an association constant 2.07 a-D-Galp 1.87...
The present study investigated 345 athletes' (male = 152, female 193) use of observational learning and imagery for practice at competition how this related to sport confidence. Functions Observational Learning Questionnaire (Cumming et al., 2005), the Sport Imagery (Hall 1998), Trait Confidence Inventory (Vealey, 1986) were contextualized by asking participants rate each item twice, once competition. athletes reported using different functions in these situations, but pattern differed....
Co-infections alter the host immune response but how systemic and local processes at site of infection interact is still unclear. The majority studies on co-infections concentrate one infecting species, an function or group cells often focus initial phase infection. Here, we used a combination experiments mathematical modelling to investigate network responses against single with respiratory bacterium Bordetella bronchiseptica gastrointestinal helminth Trichostrongylus retortaeformis. Our...
IgA and IgE activity against Teladorsagia circumcincta was investigated in a flock of Texel lambs following natural, mixed nematode infection among lambs. The distribution similar to gamma whereas different. Box-Cox analysis demonstrated that X0.25 suitable transformation normalise responses. transformed under moderate strong genetic control. Nine different allergens were identified by proteomic analysis. Tropomyosin selected for further tropomyosin moderately heritable associated with...
Cardiac ischemia reduces excitability in ventricular tissue. Acidosis (one component of ischemia) affects a number ion currents. We examined the effects extracellular acidosis (pH 6.6) on peak and late Na + current ( I ) canine cells. Epicardial endocardial myocytes were isolated, patch-clamp techniques used to record . Action potential recordings from left wedges exposed acidic Tyrode solution showed widening QRS complex, indicating slowing transmural conduction. In myocytes, exposure...
The host response to different helminth species can vary and have consequences for persistence. Often these differences are generated by changes in the dynamics intensity of immune components against parasites with distinct life history strategies. We examined rabbits primary infections gastrointestinal nematodes Trichostrongylus retortaeformis Graphidium strigosum under controlled conditions 120 days post-challenge. Results showed that developed a robust effective T. abundance quickly...
Given their global distribution and abilities to persist in the host, helminths can play a crucial role affecting risk of infections by increasing individual variation infection. Helminth co-infections are particular interest because altering host immune responses, they modify susceptibility thus intensity transmission other parasites/pathogens. The dynamics co-infection were examined using two European rabbit. Individuals simultaneously challenged with primary dose both parasites, changes...