- Gastric Cancer Management and Outcomes
- Medical Imaging and Pathology Studies
- Tracheal and airway disorders
- Cancer Diagnosis and Treatment
- Occupational and environmental lung diseases
- IgG4-Related and Inflammatory Diseases
- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Metastasis and carcinoma case studies
- Soft tissue tumor case studies
- Myasthenia Gravis and Thymoma
- Neuroblastoma Research and Treatments
- Helicobacter pylori-related gastroenterology studies
- Congenital Diaphragmatic Hernia Studies
- Gastrointestinal Tumor Research and Treatment
- Congenital Anomalies and Fetal Surgery
- Esophageal and GI Pathology
- Sarcoidosis and Beryllium Toxicity Research
- Cardiovascular Issues in Pregnancy
- Endometrial and Cervical Cancer Treatments
- Gastrointestinal disorders and treatments
- Cardiac Valve Diseases and Treatments
- Intestinal Malrotation and Obstruction Disorders
- Cancer Research and Treatments
University of Yamanashi Hospital
2016-2022
University of Yamanashi
2001-2022
Saitama Medical University
2020
National Defense Medical College
2000-2003
Citizen (Japan)
1993
Tonami General Hospital
1993
Ciliated muconodular papillary tumors (CMPTs) of the lung have been recently characterized as low-grade malignant and may be indistinguishable from adenocarcinoma in situ (AIS) because they are both abundant mucous spread along alveolar walls. Herein, we report a case CMPT with polymyalgia rheumatica (PMR)-like symptoms, which resolved after resection. After surgery, antinuclear antibody tests were performed, but no abnormalities noted. Furthermore, tumor could not distinguished AIS,...
Abstract Immunoglobulin (Ig) G4‐related disease has various clinical signs and symptoms, steroidal therapy with corticosteroids been found to be effective for treatment. Few cases of IgG4‐related associated paravertebral tumor have reported, there no reports on complete resection such a tumor. Here, we report case that was successfully resected without the need postoperative medication. An 84‐year‐old woman admitted our hospital She underwent thoracoscopic surgery, pathological examination...
Intrathoracic mesothelial cysts almost always arise in the mediastinum, and extramediastinal are extremely rare. Here we describe a case of cyst derived from chest wall pleura growing after thoracic surgery.A 63-year-old Japanese woman was referred to our department. She had undergone total hysterectomy for cervical carcinoma two lung wedge resections metastatic cancer on upper lower lobes her right lobe left lung. After surgery, an intrathoracic mass found, which grew gradually. Computed...
Descending necrotizing mediastinitis (DNM) is caused by a cervical or odontogenic infection that spreads downward to the mediastinum through anatomical spaces. Its mortality rate high, and its early diagnosis important for successful treatment. Here, we report about 14-month-old girl with DNM pyothorax who was admitted our hospital. She underwent thoracoscopic surgery (TS) drainage of administrated antibiotics. Her postoperative course uneventful. Common fever in children, even those without...
It has been proven that the Tachosuture technique is effective for preventing prolonged air leaks caused by pulmonary resection. We successfully used to treat intractable pneumothorax with interstitial pneumonia. This avoids resection and contributes acute exacerbations of
症例は30代女性.咳嗽,発熱を主訴に近医を受診し,CTで右上葉の囊胞感染を指摘された.
肝細胞癌(HCC)患者では,ウイルス肝炎治療の進歩により肝関連死亡は減少し,遠隔転移例増加が見込まれ,その治療戦略が重要になる.当科で肺切除を施行したHCC肺転移10例について,炎症の指標であるリンパ球好中球数比(NLR)とGlasgow Prognostic Score(GPS)が予後因子になりうるかと,肺切除後の予後を検討した.10例中7例に再々発を認め,6例が死亡した.多変量解析ではそれぞれNLR>2.31が肺切除後の再発に対して(P=0.043),転移数≧2個が死亡に対して(P=0.04)独立した危険因子であった.再発7例中3例はさらなる外科切除を施行し,他の4例より有意に生存期間が延長した(中央値98.6 vs 12.2ヵ月;P=0.01).HCC肺転移例において,NLR>2.31の症例は再発に注意が必要だが,再発例であっても,再切除可能ならば積極的に再切除する意義があると考えられた.
[背景と目的]井上らの開発したキャップ吸引粘膜切除法であるEMRC法は,優れた粘膜切除法であるが,フルサクションで行う場合,切除深度のコントロールは困難である。今回,我々はEMRCにより得られた病理組織標本を計測することにより,EMRCの安全性,有用性について検討を行った。[対象と方法]当科においてEMRC法で施行された粘膜切除症例42病変を対象とした。切除検体のHE染色標本を用いて切除最深部粘膜表層及び粘膜筋板との距離を計測し,隆起性病変と平坦・陥凹性病変に分け,比較検討した。また,37病変については切除切片の最大径についても計測を行い,切除深度との関係を検討した。[結果]1)切除最深部と粘膜表層及び粘膜筋板との距離はそれぞれ平均2.19±0.83mm,1.11±0.67mmであった。2)平坦・陥凹性病変の方が隆起性病変より深い位置まで採取される傾向にあった。3)切片最大径と切除深度では明らかな相関は認められなかった。[結論]EMRCでは,特に平坦・陥凹性病変の場合,穿孔に対する注意が必要ではあるが,切除前に十分な局注をすることにより安全な切除が可能と考えられた。また,安定して...
Background.While regulatory T cells (Tregs) are a poor prognostic factor for lung cancer, they may be detected as Forkhead box P3+ (FOXP3+) and cluster of differentiation (-CD) 4+ by classifying FOXP3+CD4+ into different subpopulations CD4 cells. Objectives.To classify clusters tumor-infiltrating Tregs in adenocarcinoma based on the mRNA expression levels interleukin-12 subunit alpha (IL12A) transforming growth beta 1 (TGFB1) tumor specimens. Material methods.Seventy-nine patients with were...
The lung is the most common site of metastasis in patients with renal cell carcinoma (RCC). Metastatic RCCs, even those classified as stage I, can recur after >10 years. Therefore, it critical to completely resect metastatic nodules. Here, we report case a 74-year-old man who underwent nephrectomy for RCC and was diagnosed 17 years later. nodule resected through complete thoracoscopic subsegmentectomy. He had previously undergone partial clear pT1bN0M0. During his annual follow-up, computed...
A man in his 70s was referred to our department due a 1.6 cm solid nodule the right upper lobe of lung, detected via CT examination for prostate cancer. Additionally, revealed that pulmonary vein 1 ran posterior main artery ([figure 1][1]). surgical biopsy
症例は68歳男性.頭痛,嘔吐を主訴に近医を受診した.血液検査で低ナトリウム血症を認め,難治性であったため,精査目的に当院を紹介受診となった.精査にてSIADHの診断に至り,胸部CTで前縦隔に結節を認めたことから,前縦隔腫瘍に合併したSIADHと考えて拡大胸腺摘出術を行った.腫瘍は病理組織学的に胸腺から発生した神経芽腫であった.術前治療に難渋した低ナトリウム血症は,術後速やかに改善し,症状も消失した.縦隔腫瘍にSIADHを合併することは非常に珍しい.文献上,SIADHを合併した縦隔腫瘍はほとんどが悪性腫瘍であるため,このことに留意した根治性の高い術式選択が重要である.
術後遅発穿孔をきたした小児の急性胃軸捻転の1例を経験したので報告する.患児は9歳10カ月,男児,主訴は嘔吐,腹痛,腹部膨満だった.既往は肺動脈閉鎖,心室中隔欠損症で3歳時にRastelli手術が施行されていた.3日前から嘔吐をきたし,次第に腹痛,腹部膨満を認めるようになったため紹介された.初診時,腹部は緊満し,腹部全般で圧痛を認めた.腹部CTで,胃の短軸捻転を指摘,上部消化管造影で,前庭部はbeak像を呈し十二指腸へ造影剤の流出を認めなかった.急性胃軸捻転と診断し緊急開腹した.捻転を用手整復すると胃壁の色調は概ね改善したが,体下部に壁の色調の改善を認めない部分を認め,部分切除した.標本では粘膜障害が標本の切除縁まで及んでいた.術後4日目にドレーンから暗黒色の排液を認め再開腹手術を施行した.前回切除部分の癒合は良好だったが,胃体上部に多発穿孔を認め,穿孔部分を切除し洗浄ドレナージを施行,術後は良好に経過した.
Pulmonary chondroma, a component of Carney's triad, is commonly unilateral and multiple, progresses slowly. Herein, we report case chondrogenic tumour that grew proliferated during follow-up.A female patient in her 20s presenting with cough was found to have 1.4-cm nodule the left lung on computed tomography (CT). After 18 months' follow-up, CT revealed original had increased 2.2 cm, new 1.3-cm appeared. She then referred our hospital underwent robot-assisted lower lobectomy lung. The...