A5046186005- Neural dynamics and brain function
- Memory and Neural Mechanisms
- Neural and Behavioral Psychology Studies
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neural Engineering
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Neuroscience and Neuropharmacology Research
- Quantum Information and Cryptography
- Zebrafish Biomedical Research Applications
- Quantum Mechanics and Applications
- Decision-Making and Behavioral Economics
- Dementia and Cognitive Impairment Research
- Neurobiology of Language and Bilingualism
- Sports Analytics and Performance
- Photoreceptor and optogenetics research
- Quantum Computing Algorithms and Architecture
- Neurological disorders and treatments
- Receptor Mechanisms and Signaling
Gladstone Institutes
2015-2019
Yale University
2008-2018
University of New Mexico
2009-2011
Los Alamos National Laboratory
2003
We describe an error-reconciliation protocol, which we call Winnow, based on the exchange of parity and Hamming's ``syndrome'' for N-bit subunits a large dataset. The Winnow protocol was developed in context quantum-key distribution offers significant advantages net higher efficiency compared to other widely used protocols within quantum cryptography community. A detailed mathematical analysis is presented practical implementations distribution; particular, information overhead required...
Although human and animal behaviors are largely shaped by reinforcement punishment, choices in social settings also influenced information about the knowledge experience of other decision-makers. During competitive games, monkeys increased their payoffs systematically deviating from a simple heuristic learning algorithm thereby countering predictable exploitation computer opponent. Neurons dorsomedial prefrontal cortex (dmPFC) signaled animal's recent choice reward history that reflected...
ABSTRACT The striatum is thought to play a central role in action selection and reinforcement, optogenetic experiments suggest differential roles for direct- indirect-pathway medium spiny neurons (dMSNs iMSNs). However, the encoding of value-related information dMSNs iMSNs during adaptive decision-making not well understood. We trained mice on dynamic foraging task where they had learn value different options based their recent history choices outcomes. Single-cell calcium imaging...
Reinforcement has long been thought to require striatal synaptic plasticity. Indeed, direct manipulations such as self-stimulation of direct-pathway projection neurons (dMSNs) are sufficient induce reinforcement within minutes. However, it’s unclear what role, if any, is played by downstream circuitry. Here, we used dMSN in mice a model for striatum-driven and mapped the underlying circuitry across multiple basal ganglia nuclei output targets. We found that mimicking effects activation on...