- Anesthesia and Pain Management
- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Opioid Use Disorder Treatment
- Pain Management and Opioid Use
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Artificial Intelligence in Healthcare and Education
- Spaceflight effects on biology
- Cardiac, Anesthesia and Surgical Outcomes
- Myofascial pain diagnosis and treatment
- Shoulder Injury and Treatment
- Spinal Hematomas and Complications
- Cannabis and Cannabinoid Research
- Pediatric Pain Management Techniques
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Space Exploration and Technology
- Pain Mechanisms and Treatments
- Poisoning and overdose treatments
- Epilepsy research and treatment
- Prenatal Substance Exposure Effects
- Botulinum Toxin and Related Neurological Disorders
- Clinical Reasoning and Diagnostic Skills
- Interpreting and Communication in Healthcare
- Peripheral Nerve Disorders
University of California, Irvine
2016-2025
Johnson Space Center
2024-2025
The University of Texas Medical Branch at Galveston
2024-2025
University of California, Irvine Medical Center
2023-2025
University of Colorado System
2024
Baylor College of Medicine
2024
University of Colorado Anschutz Medical Campus
2024
Glenn Research Center
2024
The University of Texas Health Science Center at San Antonio
2017
The University of Texas Health Science Center at Houston
2017
Background Intra-articular corticosteroid (IACS) injection and peri-articular are commonly used to treat musculoskeletal conditions. Results vary by region, but most studies report short-term benefit with mixed results on long-term relief. Publications showed adverse events from single injections. Recommended effective doses were lower than those currently clinicians. Methods Development of the practice guideline for joint injections was approved Board Directors American Society Regional...
Background Accurate, objective pain assessment is required in the health care domain and clinical settings for appropriate management. Automated, detection from physiological data patients provides valuable information to hospital staff caregivers better manage pain, particularly who are unable self-report. Galvanic skin response (GSR) one of physiologic signals that refers changes sweat gland activity, which can identify features emotional states anxiety induced by varying levels. This...
Background: This study assesses the effectiveness of large language models (LLMs) in simplifying complex within orthopaedic patient education materials (PEMs) and identifies predictive factors for successful text transformation. Methods: We transformed 48 PEMs using GPT-4, GPT-3.5, Claude 2, Llama 2. The readability, quantified by Flesch-Kincaid Reading Ease (FKRE) Grade Level (FKGL) scores, was measured before after Analysis included characteristics such as syllable count, word length,...
Opioids disrupt sleep and adenosine promotes sleep, but no studies have characterized the effects of opioids on levels in brain regions known to regulate states arousal. Delivering pontine reticular formation (PRF) substantia innominata (SI) region basal forebrain disrupts sleep. In contrast, administering agonists PRF or SI increases These findings encouraged current study testing hypothesis that microdialysis delivery decreases SI, respectively.A probe was placed isoflurane anesthetized...
Background There is a strong demand for an accurate and objective means of assessing acute pain among hospitalized patients to help clinicians provide medications at proper dosage in timely manner. Heart rate variability (HRV) comprises changes the time intervals between consecutive heartbeats, which can be measured through acquisition interpretation electrocardiography (ECG) captured from bedside monitors or wearable devices. As increased sympathetic activity affects HRV, index autonomic...
Artificial intelligence (AI) tools are currently expanding their influence within healthcare. For pain clinics, unfettered introduction of AI may cause concern in both patients and healthcare teams. Much the stems from lack community standards understanding how algorithms function. Data literacy can be challenging even for experienced providers as these topics not incorporated into standard clinical education pathways. Another reasonable involves potential encoding bias screening treatment...
PURPOSE: To determine whether hinge position has an effect on corneal sensation and dry-eye symptoms after myopic laser in situ keratomileusis (LASIK) performed with the IntraLase femtosecond (IntraLase Corp.). SETTING: University-based academic practice, Ann Arbor, Michigan, USA. METHODS: Sixty-six consecutive eyes of 33 patients were prospectively evaluated a randomized contralateral-eye study to compare difference between superior-hinge temporal-hinge locations bilateral LASIK laser....
Background Although uncertainties exist regarding implementation, artificial intelligence–driven generative language models (GLMs) have enormous potential in medicine. Deployment of GLMs could improve patient comprehension clinical texts and low health literacy. Objective The goal this study is to evaluate the ChatGPT-3.5 GPT-4 tailor complexity medical information patient-specific input education level, which crucial if it serve as a tool addressing Methods Input templates related 2...
Purpose of review Artificial intelligence (AI) represents a transformative opportunity for pain medicine, offering potential solutions to longstanding challenges in assessment and management. This synthesizes the current state AI applications with strategic framework implementation, highlighting established adaptation pathways from adjacent medical fields. Recent findings In acute pain, systems have achieved regulatory approval ultrasound guidance regional anesthesia shown promise automated...
To characterize the incidence, severity, quality, and treatment of pain in a large cohort Marfan patients.A web-based survey was distributed to all individuals on Foundation listserv. Respondents who endorsed diagnosis syndrome were queried as presence, frequency, location, quality their asked describe specific treatments used manage pain. The primary outcome presence symptoms respondents during 7-day period preceding completion survey.Of 993 patients with verified syndrome, 67% (95%...
There is potential for adverse events from corticosteroid injections, including increase in blood glucose, decrease bone mineral density and suppression of the hypothalamic-pituitary axis. Published studies note that doses lower than those commonly injected provide similar benefit.
From the *Department of Anesthesiology and Perioperative Medicine, Mayo Clinic Hospital, Rochester, Minnesota †Department Anesthesia, University Virginia, Charlottesville, Virginia ‡Department Care, California Irvine School Irvine, California. Accepted for publication August 27, 2024. Conflicts Interest, Funding: Please see DISCLOSURES at end this article. Reprints will not be available from authors. Address correspondence to Ryan S. D'Souza, MD, Department Clinic, MN. e-mail [email protected].
Abstract Background Translating innovative research advancements into commercially viable medical interventions presents well-known challenges. However, there is limited understanding of how specific patient, clinical, social, and legal complexities have further complicated delayed the development new effective for Opioid Use Disorder (OUD). We present following case studies to provide introductory business insights researchers, professionals, entrepreneurs who are considering or currently...
No study has compared cervical interlaminar epidural steroid injection (CIESI) with catheter advancement to the side and level of pathology versus standard C7-T1 CIESI. This investigated whether radicular pain is more effectively treated by CIESI a targeted approach.Prospective, randomized, single-blinded trial.Numerical Rating Scale (NRS) at 1 month.Oswestry Neck Disability Index (ONDI), Pain (PDI), McGill Questionnaire (MPQ), Patient Global Impression Change (PGIC), daily morphine...
Background Assessment of pain is critical to its optimal treatment. There a high demand for accurate objective assessment effectively optimizing management interventions. However, multivalent, dynamic, and ambiguous phenomenon that difficult quantify, particularly when the patient’s ability communicate limited. The criterion standard intensity self-reporting. this unidimensional model disparaged oversimplification limited applicability in several vulnerable patient populations. Researchers...
Abstract Objective The US CDC identified prescription drug monitoring programs (PDMPs) as a tool to address the contemporary opioid crisis, but few studies have investigated PDMP usability and effectiveness from users’ perspective. Even fewer considered how practices differ across medical domains. In this study, we aimed these gaps, soliciting perspectives on PDMPs providers contending with crisis: physicians working in emergency departments (EDs) pain management clinics. We provide...
The United States faces an opioid crisis. Integrating prescription drug monitoring programs into electronic health records offers promise to improve prescribing practices. This study aimed evaluate 2 different user interface designs for program and record integration.Twenty-four resident physicians participated in a randomized controlled experiment using 4 simulated patient cases. In the conventional condition, histories were presented tabular format, computerized clinical decision support...