Mohd Ashif Khan

ORCID: 0000-0003-1576-8779
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About
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Research Areas
  • Cancer-related cognitive impairment studies
  • Advancements in Transdermal Drug Delivery
  • Tryptophan and brain disorders
  • Glioma Diagnosis and Treatment
  • Essential Oils and Antimicrobial Activity
  • Cancer survivorship and care
  • Hepatitis C virus research
  • Bee Products Chemical Analysis
  • Wound Healing and Treatments
  • Sleep and Wakefulness Research
  • COVID-19 Clinical Research Studies
  • Childhood Cancer Survivors' Quality of Life
  • Family Support in Illness
  • Hematological disorders and diagnostics
  • Computational Drug Discovery Methods
  • Urinary Tract Infections Management
  • Acute Myeloid Leukemia Research
  • Bone and Joint Diseases
  • Systemic Lupus Erythematosus Research
  • Synthesis and biological activity
  • Melanoma and MAPK Pathways
  • Dermatology and Skin Diseases
  • Hematopoietic Stem Cell Transplantation
  • Neutropenia and Cancer Infections
  • Long-Term Effects of COVID-19

Jamia Hamdard
2015-2025

infection is linked to gastritis, ulcers and gastric cancer. Nanomedicine offers a promising solution by utilizing nanoparticles for precise drug delivery, countering antibiotic resistance delivery issues. Nanocarriers such as liposomes enhance stability circulation, targeting sites through mucosa characteristics. Challenges include biocompatibility, stability, scalability personalized therapies. Despite obstacles, nanomedicine's potential reshaping

10.2217/fmb-2023-0189 article EN Future Microbiology 2024-02-21

Abstract: Insomnia is becoming a concern in general practice as it affects around 30% of adults. It sleep disorder characterized by trouble getting asleep, staying waking up early, and difficulty falling back to sleep. The most commonly used hypnotics, such benzodiazepines, Z drugs, etc, are associated with various issues, including psychomotor cognitive impairment. Dual orexin receptor antagonists an emerging class hypnotics treat insomnia. Suvorexant first-in-class dual antagonist approved...

10.2174/0115748863337982250212111648 article EN Current Drug Safety 2025-03-03

Epilepsy and seizures are characterized by neuronal hyperexcitability damage, influenced metabolic dysregulation, neuroinflammation, oxidative stress. Despite available treatments, many patients remain resistant to therapy, necessitating novel therapeutic strategies. Klotho, a neuroprotective, anti-inflammatory, antioxidative protein has emerged as potential modulator of epilepsy-related pathways. This study investigates the physostigmine analogues in regulating Klotho expression its...

10.3389/fphar.2025.1580943 article EN cc-by Frontiers in Pharmacology 2025-04-25

Abstract Topical application of BRAF inhibitors has been shown to accelerate wound healing in murine models, which can be extrapolated into clinical applications. The aim the study was identify suitable pharmacological targets and elucidate their mechanisms action for therapeutic applicability healing, by employing bioinformatics tools including network pharmacology molecular docking. potential were obtained from SwissTargetPrediction, DrugBank, CTD, Therapeutic Target Database, Binding...

10.1002/jcb.30430 article EN Journal of Cellular Biochemistry 2023-06-19

A diabetic wound is one of the major complications arising from hyperglycemia, neuropathy, and oxidative stress in patients. Finding effective treatments for wounds has been difficult owing to complex pathophysiology environments. Chronic are notoriously treat with conventional care methods. In recent years, polyphenols found plants have received much interest as a potential treatment wounds. Their key benefits their safety fact that they act through many molecular routes However, problems...

10.2174/0118715303242310230927104709 article EN Endocrine Metabolic & Immune Disorders - Drug Targets 2023-10-11

Abstract Background Anthracyclines-based regimen (5-fluorouracil, doxorubicin, and cyclophosphamide (FAC); cyclophosphamide, epirubicin, 5-fluorouracil [CEF]) non-anthracycline based regimens (cyclophosphamide, methotrexate, [CMF]) are widely used as neoadjuvant chemotherapy for breast cancer patients. Objective The present study was conducted to observe the effects of FAC, CEF, CMF on cognition circulatory proinflammatory cytokines (interleukin 6 [IL-6] interleukin 1β [IL-1β]) duration...

10.1055/s-0042-1755234 article EN cc-by Arquivos de Neuro-Psiquiatria 2022-08-01

ABSTRACT Background: Co-morbid diabetes and depression are prevalent chronic conditions negatively affecting quality of life (QoL). Inflammation has been considered as an integral mechanism in patients with both depression. Objective: The aim the present study was to investigate its association interleukins (IL)-1β IL-9 type 2 diabetic (T2DM) controls. QoL patient also assessed. Methods: Eighty subjects were included, distributed among three groups: Group 1 - Healthy controls; T2DM without...

10.1590/0004-282x20190177 article EN cc-by Arquivos de Neuro-Psiquiatria 2020-05-01
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