- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Graphene and Nanomaterials Applications
- 3D Printing in Biomedical Research
- Wound Healing and Treatments
- Bone Tissue Engineering Materials
- RNA Interference and Gene Delivery
- Silk-based biomaterials and applications
- biodegradable polymer synthesis and properties
- Gold and Silver Nanoparticles Synthesis and Applications
- Photodynamic Therapy Research Studies
- Advanced biosensing and bioanalysis techniques
- Advanced Drug Delivery Systems
- Photopolymerization techniques and applications
- Advanced Polymer Synthesis and Characterization
- Cancer Cells and Metastasis
- Advanced Nanomaterials in Catalysis
- Hydrogels: synthesis, properties, applications
- Advancements in Transdermal Drug Delivery
- Tissue Engineering and Regenerative Medicine
- Ocular Surface and Contact Lens
- Surgical Sutures and Adhesives
University of Beira Interior
2015-2024
University of Coimbra
2018-2024
National Council for Scientific and Technological Development
2019-2020
Health Sciences Centre
2015-2020
John Wiley & Sons (United States)
2018
Hudson Institute
2018
Hospital Center of Cova da Beira
2014
Weatherford College
2014
Escola Superior de Saúde Egas Moniz
2012
Hospital de Santa Maria
2010
Wound healing is a complex process involving an integrated response by many different cell types and growth factors in order to achieve rapid restoration of skin architecture function. The present study evaluated the applicability chitosan hydrogel (CH) as wound dressing. Scanning electron microscopy analysis was used characterize CH morphology. Fibroblast cells isolated from rat were assess cytotoxicity hydrogel. able promote adhesion proliferation. Cell viability studies showed that its...
Today, none of the wound dressings available on market is fully capable reproducing all features native skin. Herein, an asymmetric electrospun membrane was produced to mimic both layers It comprises a top dense layer (manufactured with polycaprolactone) that designed provide mechanical support and bottom porous (composed chitosan Aloe Vera) aimed improve bactericidal activity ultimately healing process. The results obtained revealed membranes displayed porosity, wettability, as well...
Blue: Biocompatible and biodegradable water-soluble dendrimers comprising ureas within the interior amino groups on periphery were synthesized in supercritical carbon dioxide (dendrimer of generation 1 shown picture). This novel class shows a pH-dependent intrinsic blue fluorescence at very low concentrations, which makes them potential polymeric fluorescent cell markers. Detailed facts importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed,...
Three-dimensional (3D) cell culture models of solid tumors are currently having a tremendous impact in the vitro screening candidate anti-tumoral therapies. These 3D provide more reliable results than those provided by standard 2D cultures. However, manufacturing techniques need to be further optimized order increase robustness these and data that can properly correlated with vivo situation. Therefore, present study parameters used for producing multicellular tumor spheroids (MCTS) liquid...