One of the most crucial approaches for treating human diseases, particularly parasite infections, is nanomedicine. significant protozoan diseases that impact farm and domestic animals coccidiosis. While, amprolium one traditional anticoccidial medication, advent drug-resistant strains Eimeria necessitates development novel treatments. The goal current investigation was to determine whether biosynthesized selenium nanoparticles (Bio-SeNPs) using Azadirachta indica leaves extract might treat...

Coccidiosis has a considerable economic loss in the poultry industry where parasite Eimeria affect animal survival. Natural products emerge as an essential and complementary means of controlling avian coccidiosis, addition to anticoccidial medications. The current study examined antioxidant activity Rumex nervosus leaf extract (RE) chickens infected with tenella. RE was able decrease induced weight due infection. Also, significantly suppressed oocysts released chickens' faeces. Moreover,...

Malaria is a major public health problem caused by the apicomplexan Plasmodium parasite. Cerebral malaria (CM) most critical outcome of infection. It becoming more difficult to manage, particularly in areas multi-drug resistance. Scientists are focused on identifying alternative strategies combat Therefore, this study was designed evaluate activity Juglans regia leaf extract (JRLE) berghei-infected C57BL/6 mice. The J. prepared using methanol and characterized Fourier-transform infrared...

Human infection with parasites is still one of the big problems worldwide. Medicinal plants succeeded to overcome a variety protozoan and helminthic parasites. In this study, Salvadora persica root extracts (SE) were used treat helminthosis coccideosis. Three doses (200, 100 50 mg/ml) study anthelmintic activity S. persica. Allolobophora caliginosa was as model worm. Also, Albendazole reference drug. order anticoccideal SE, group mice infected Eimeria papillata sporulated oocysts....

ABSTRACT Eimeria is the parasite that responsible for eimeriosis in gut of numerous domestic mammals. While treating eimeriosis, use medication and some effects synthetic anticoccidials has led to development resistant parasites, necessitating search alternative treatments. The treatment a wide variety diseases can be done with natural products don't harm environment. goal current investigation was determine how Artemisia judaica leaf extract (AJLE) affected oocyst sporulation papillate...

Background: The plants are considered to be living chemical factories responsible for the production of a wide variety secondary metabolites (SMs). Geographical and ecological differences result in different compositions even within same plant. Medicinal promising options at antiparasitic. this study aimed examine impact Eucalyptus camaldulensis leaf extracts (ECES) from sandy environments on histological changes gene expression caused by Plasmodium chabaudi infection liver. Methods: We...

Eimeriosis is caused by a protozoan parasite of the genus Eimeria and infection affecting most domestic animal species. The aim this research was to comprehend impact selenium nanoparticles (SeNPs) on eimeriosis induced papillata in mouse jejunum, how they work as antioxidants anti-apoptotic agents against eimeriosis. numbers meronts, gamonts, developing oocysts E. reduced after infected mice were treated with SeNPs. levels malondialdehyde (MDA), nitric oxide (NO), other oxidative...

Abstract Coccidiosis is the most prevalent disease-causing widespread economic loss among farm and domestic animals. Currently, several drugs are available for control of this disease but resistance has been confirmed all them. There an urgent need, therefore, identification new sources as alternative treatments to coccidiosis. The present work aimed study effect Persea americana extract (PAE) anti-coccidial, anti-oxidant, anti-apoptotic modulator during murine intestinal Eimeria papillata...

Nanomedicine is one of the most important methods used to treat human diseases including parasitic diseases. Schistosomiasis a major disease that affects health in tropical regions. Whilst Praziquantel main classic antischistosomal drug, new drugs are required due poor effect drug on parasite juveniles and immature worms, emergence resistant strains Schistosoma. The present study aimed examine curative roles both gold selenium nanoparticles jejunal tissues mice infected with Schistosoma...

The present study aimed to investigate the protective role of berberine (BER) against Plasmodium chabaudi-induced infection in mice. Animals were divided into three groups. Group I served as a vehicle control. II and group III infected with 1000 P. chabaudi erythrocytes. was gavaged 100 μl 10 mg/kg chloride for days. All mice sacrificed at day post-infection. percentage parasitemia significantly reduced more than 30%, after treatment BER. Infection caused marked hepatic injuries indicated by...

Cadmium, present in the environment, accumulates different organs of animals and humans, has deleterious effects on kidney. In this study, we investigated protective methanolic extract Pleurotus ostreatus comparison with silymarin renal function cadmium-intoxicated rats for five days. Rats intraperitoneally injected cadmium chloride (1 mg/kg). These were treated either P. (200 mg/kg) or to investigate extract. Cadmium treatment induced significant histopathological impairments increased...

Background: Medicinal plants that are abundant in physiologically active phytochemicals have long been used traditional medicine. Due to their anti-inflammatory and antioxidant qualities, several of these can lower the chance developing certain illnesses. Coccidiosis is a disease affects many animals results large financial losses. Eimeria spp. strains resistant drugs emerged as result drug addiction overuse. Therefore, Teucrium polium leaves ethanolic extract (TPLE) was assessed on...

Background: Teucrium polium is an herb utilized in traditional medicine for its biological activity. In the present study, T. leaves ethanolic extract (TPLEE) was investigated effects on coccidiosis resulting from Eimeria papillata infection mice. Methods: vivo, TPLEE (150 mg/kg) administered antioxidant and hepatoprotective properties. The anticoccidial anti-inflammatory of were evaluated by measuring oocyst suppression assessing liver histopathology, respectively. Result: Indicated that...

Coccidiosis affects both domestic and wild animals negatively impacting industries worldwide. Medicinal plants are widely used against parasites. Using infected mice with Eimeria papillata, we assessed the anticoccidial impact of Zingiber officinale extract (ZE). The in first group were just given distilled water, while second ZE. parasite's oocysts into third fourth groups. was ZE for five days. faeces reduced after treatment total parasitic stages treatments by about 50%. Also, gamonts,...

Trypanosomiasis is a neglected tropical disease, transmitted by blood-sucking insects and can affect humans animals, depending on the species of Trypanosoma parasite. has acquired resistance to majority drugs used; hence, alternative medicines are required. Indigofera oblongifolia leaf extract (IOE) been shown treat blood stage malaria. Here, IOE was used demonstrate its effect evansi-infected mice. Analysis gas chromatography-mass spectrometry showed presence many active components like...

Eimeriosis is a global poultry health problem. In the current study, we investigated role of Salvadora persica leaf extracts (SE) against murine eimeriosis induced by Eimeria papillata. The infection an oocyst output 6242 ± 731 oocysts/g feces. After treatment with 300 mg⁄kg SE, oocysts expelled in feces decreased approximately 3-fold. addition, total number E. papillata parasitic stage jejunum mice after SE. SE significantly reduced apoptotic cells 2-fold infected jejunum. ameliorated...

Malaria is a dangerous disease spread across several countries. Recent studies have focused on medicinal plants to discover alternative agents the currently used drugs for malaria treatment. Here, we investigated potential role of Indigofera oblongifolia leaf extract (IE) hepatic inflammation in mice with Plasmodium chabaudi -infected erythrocytes. Female C57BL/6 were divided into three groups. The first group served as control noninfected group, while second and third groups...

Malaria is a worldwide serious‐threatening infectious disease caused by Plasmodium and the parasite resistance to antimalarial drugs has confirmed significant obstacle novel therapeutic drugs. In this article, we assessed antioxidant anti‐inflammatory activity of nanoparticles prepared from Indigofera oblongifolia extract (AgNPs) against infection with chabaudi in mice spleen. AgNPs could significantly suppress parasitaemia approximately 98% on day 7 postinfection P. improve...